lcn12
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  • Official Full Name
  • lipocalin 12
  • Background
  • Members of the lipocalin family, such as LCN12, have a common structure consisting of an 8-stranded antiparallel;beta-barrel that forms a cup-shaped ligand-binding pocket or calyx. Lipocalins generally bind small hydrophobic;ligands and transport them to specific cells (Suzuki et al., 2004 (PubMed 15363845)).
  • Synonyms
  • LCN12; lipocalin 12; epididymal-specific lipocalin-12; MGC48935; Lipocalcin 12; MGC34753
Cat.#:LCN12-500HTag:His/GST
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human LCN12 Protein, His/GST-tagged
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Cat.#:Lcn12-501MTag:His/GST
Source (Host):E. coliSpecies:Mouse
Product nameRecombinant Mouse Lcn12 Protein, His/GST-tagged
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Cat.#:Lcn12-502RTag:His/GST
Source (Host):E. coliSpecies:Rat
Product nameRecombinant Rat Lcn12 Protein, His/GST-tagged
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Cat.#:LCN12-2477RTag:His
Source (Host):Mammalian CellsSpecies:Rhesus Macaque
Product nameRecombinant Rhesus monkey LCN12 Protein, His-tagged
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Cat.#:LCN12-975HCLTag:
Source (Host):Species:Human
Product nameRecombinant Human LCN12 cell lysate
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Involved Pathway

LCN12 involved in several pathways and played different roles in them. We selected most pathways LCN12 participated on our site, such as SLC-mediated transmembrane transport, Transmembrane transport of small molecules, Transport of fatty acids, which may be useful for your reference. Also, other proteins which involved in the same pathway with LCN12 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
Pathway Name
Pathway Related Protein
SLC-mediated transmembrane transport
SLC4A2A; SLC5A6B; SLC39A6; SLC12A1; SLC29A2; SLC17A7A; SLC13A4; SLC38A4; SLC17A1; RHCG2A
Transmembrane transport of small molecules
WNK1; HTR3C; SLC8A2A; LCN9; SLC27A4; SLC15A3; ANO9; CP; SLC6A7; SLC2A10
Transport of fatty acids
APOD; LCN12; SLC27A4; LCN9; LCN15; LCN1
Transport of vitamins, nucleosides, and related molecules
SLC35B4; SLCO4A1; SLCO2B1; SLC5A6A; LCN15; SLC35A2; SLC28A1; LCN12; SLC27A4; SLC29A2

Protein Function

LCN12 has several biochemical functions, for example, retinoic acid binding, transporter activity. Some of the functions are cooperated with other proteins, some of the functions could acted by LCN12 itself. We selected most functions LCN12 had, and list some proteins which have the same functions with LCN12. You can find most of the proteins on our site.
Function
Related Protein
Function retinoic acid binding
Related Protein CYP26A1; CRABP2B; UGT1A1; CYP26B1; UGT1A2; LCN12; RARA; SERPINA5; NR2F2; PTGDSB
Function transporter activity
Related Protein ABCA4A; RBP1; ABCB8; FABP10A; CRABP2A; OSTA; AQP8A.1; TMEM184BA; SLCO2B1; AQP11

Interacting Protein

LCN12 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with LCN12 here. Most of them are supplied by our site. Hope this information will be useful for your research of LCN12.
MYC

LCN12 Related Articles

Cheng, L; Xing, H; et al. Lipocalin-2 Promotes M1 Macrophages Polarization in a Mouse Cardiac Ischaemia-Reperfusion Injury Model. SCANDINAVIAN JOURNAL OF IMMUNOLOGY 81:31-38(2015).
Ginde, AA; Blatchford, PJ; et al. AGE-RELATED DIFFERENCES IN BIOMARKERS OF ACUTE INFLAMMATION DURING HOSPITALIZATION FOR SEPSIS. SHOCK 42:99-107(2014).