ltb4r2
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  • Official Full Name
  • leukotriene B4 receptor 2
  • Background
  • Low-affinity receptor for leukotrienes including leukotriene B4. Mediates chemotaxis of granulocytes and macrophages. The response is mediated via G-proteins that activate a phosphatidylinositol-calcium second messenger system. The rank order of affinities for the leukotrienes is LTB4 > 12-epi-LTB4 > LTB5 > LTB3.
  • Synonyms
  • LTB4R2; leukotriene B4 receptor 2; BLT2; NOP9; BLTR2; JULF2; KPG_004; LTB4-R2; LTB4-R 2; LTB4 receptor JULF2; leukotriene B4 receptor BLT2; seven transmembrane receptor BLTR2;
Cat.#:LTB4R2-9346MTag:His
Source (Host):Mammalian CellsSpecies:Mouse
Product nameRecombinant Mouse LTB4R2 Protein
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Cat.#:LTB4R2-3499RTag:His
Source (Host):Mammalian CellsSpecies:Rat
Product nameRecombinant Rat LTB4R2 Protein
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Cat.#:LTB4R2-9166HCLTag:
Source (Host):Species:Human
Product nameRecombinant Human LTB4R2 293 Cell Lysate
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Cat.#:CSC-RG0280Tag:
Source (Host):Species:Human
Product nameHuman LTB4R2-FLAG Stable Cell Line-HEK293T
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Involved Pathway

LTB4R2 involved in several pathways and played different roles in them. We selected most pathways LTB4R2 participated on our site, such as Calcium signaling pathway, Neuroactive ligand-receptor interaction, which may be useful for your reference. Also, other proteins which involved in the same pathway with LTB4R2 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
Pathway Name
Pathway Related Protein
Calcium signaling pathway
ADRA1BB; P2RX2; SLC8A3; CALM1; CALM3B; HTR6; VDAC2; CACNA1G; ATP2B1; DRD7
Neuroactive ligand-receptor interaction
HTR1AA; GRIN2A; GABRR3; S1PR5; CALCR; PTH1R; CHRNA10; CHRNE; TAAR14H; HTR1E

Protein Function

LTB4R2 has several biochemical functions, for example, G-protein coupled peptide receptor activity, leukotriene B4 receptor activity, leukotriene receptor activity. Some of the functions are cooperated with other proteins, some of the functions could acted by LTB4R2 itself. We selected most functions LTB4R2 had, and list some proteins which have the same functions with LTB4R2. You can find most of the proteins on our site.
Function
Related Protein
Function G-protein coupled peptide receptor activity
Related Protein LHCGR; CYSLTR2; LTB4R; GPR37; MCHR2; MC1R; GRPR; TSHR; FSHR; RXFP3
Function leukotriene B4 receptor activity
Related Protein LTB4R2; LTB4R
Function leukotriene receptor activity
Related Protein CYSLTR2; LTB4R; LTB4R2; CYSLTR1

Interacting Protein

LTB4R2 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with LTB4R2 here. Most of them are supplied by our site. Hope this information will be useful for your research of LTB4R2.
AKT1

LTB4R2 Related Articles

Guerrero, ATG; Verri, WA; et al. Involvement of LTB4 in zymosan-induced joint nociception in mice: participation of neutrophils and PGE(2). JOURNAL OF LEUKOCYTE BIOLOGY 83:122-130(2008).
Yan, Y; Wang, BX; et al. Inhibitory effects of mizolastine on ultraviolet B-induced leukotriene B4 production and 5-lipoxygenase expression in normal human dermal fibroblasts in vitro. PHOTOCHEMISTRY AND PHOTOBIOLOGY 82:665-669(2006).