• Official Full Name
  • melanoma antigen family A, 6
  • Background
  • This gene is a member of the MAGEA gene family. The members of this family encode proteins with 50 to 80% sequence identity to each other. The promoters and first exons of the MAGEA genes show considerable variability, suggesting that the existence of this gene family enables the same function to be expressed under different transcriptional controls. The MAGEA genes are clustered at chromosomal location Xq28. They have been implicated in some hereditary disorders, such as dyskeratosis congenita. Two transcript variants encoding the same protein have been identified for this gene.
  • Synonyms
  • MAGEA6; melanoma antigen family A, 6; MAGE6; melanoma-associated antigen 6; cancer/testis antigen family 1; member 6; CT1.6; MAGE 6 antigen; melanoma antigen family A 6; melanoma associated antigen 6; Cancer/testis antigen 1.6; MAGA6_HUMAN; MAGE 3b; MAGE-6 antigen; MAGE3B; MAGE3B antigen; OTTHUMP00000024223; OTTHUMP00000024224; OTTHUMP00000205538; cancer/testis antigen family 1, member 6; MAGE-3b
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human MAGEA6 protein, T7/His-tagged
Source (Host):Wheat germSpecies:Human
Product nameRecombinant Human MAGEA6
Source (Host):Mammalian CellsSpecies:Human
Product nameRecombinant Human MAGEA6
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human Melanoma Antigen Family A, 6, His-tagged
Source (Host):Species:Human
Product nameRecombinant Human MAGEA6 293 Cell Lysate

Protein Function

MAGEA6 has several biochemical functions, for example, molecular_function, protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by MAGEA6 itself. We selected most functions MAGEA6 had, and list some proteins which have the same functions with MAGEA6. You can find most of the proteins on our site.
Related Protein
Function molecular_function
Related Protein GSDMC4; D8ERTD738E; DSCR9; ANKRD52A; ZP3.2; CTU1; NIPAL4; CAR6; SEPT3; MCART1
Function protein binding
Related Protein GTF3C5; METTL15; FBXL3; PRKACA; CCDC148; LOC729991; FAM64A; HMGN4; GCHFR; ZWINT

Interacting Protein

MAGEA6 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with MAGEA6 here. Most of them are supplied by our site. Hope this information will be useful for your research of MAGEA6.

MAGEA6 Related Articles

Lee, OJ; Son, SM; et al. CEACAM6 as detected by the AP11 antibody is a marker notable for mucin-producing adenocarcinomas. VIRCHOWS ARCHIV 466:151-159(2015).
Zhang, QM; He, SJ; et al. Overexpression of MAGE-D4 in colorectal cancer is a potentially prognostic biomarker and immunotherapy target. INTERNATIONAL JOURNAL OF CLINICAL AND EXPERIMENTAL PATHOLOGY 7:3918-3927(2014).