Recombinant Human Melanoma Antigen Family A, 6, His-tagged

• Cat.No.: MAGEA6-6788H
• Product Overview: Recombinant humanMAGEA6 protein, fused to His-tag at C-terminus, was expressed in E.coli andpurified by using conventional chromatography techniques.

Specification

• Species: Human
• Source: E.coli
• Tag: His
• Description: MAGEA6 is a memberof the MAGEA family, which directs the expression of tumor antigens that arerecognized on a human melanoma by autologous cytolytic T lymphocytes (CTL).The MAGE genes were initially isolated from different kinds of tumors, andbased on their virtually exclusive tumor-specific expression in adulttissues, they have been used as targets for cancer immunotherapy
• Form: Liquid. In 20mMTris-HCl buffer (pH 8.0) containing 0.1M NaCl, 10% glycerol, 1mM DTT
• Molecular Weight: 35.9 kDa (322aa),confirmed by MALDI-TOF
• Purity: > 90% by SDS -PAGE
• Concentration: 1 mg/ml (determinedby Bradford assay)
• Sequences of aminoacids: MPLEQRSQHCKPEEGLEARG EALGLVGAQA PATEEQEAAS SSSTLVEVTL GEVPAAESPD PPQSPQGASS LPTTMNYPLWSQSYEDSSNQ EEEGPSTFPD LESEFQAALS RKVAKLVHFL LLKYRAREPV TKAEMLGSVV GNWQYFFPVIFSKASDSLQL VFGIELMEVD PIGHVYIFAT CLGLSYDGLL GDNQIMPKTG FLIIILAIIA KEGDCAPEEKIWEELSVLEV FEGREDSIFG DPKKLLTQYF VQENYLEYRQ VPGSDPACYE FLWGPRALIE TSYVKVLHHMVKISGGPRIS YPLLHEWALR EGEELEHHHH HH
• Storage: Can be stored at+4°C short term (1-2 weeks). For long term storage, aliquot and store at-20°C or -70°C. Avoid repeated freezing and thawing cycles.

Gene Information

• Gene Name: MAGEA6melanoma antigen family A, 6 [ Homo sapiens ]
• Official Symbol: MAGEA6
• Synonyms: MAGEA6; melanoma antigen family A,6; MAGE6; melanoma-associated antigen 6; cancer/testis antigen family 1;member 6; CT1.6; MAGE 6 antigen; melanoma antigen family A 6; melanomaassociated antigen 6
• Gene ID: 4105
• mRNA Refseq: NM_005363
• Protein Refseq: NP_005354
• MIM: 300176
• Uniprot ID: P43360
• Chromosome Location: Xq28
• Function: molecular_function