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MARK2

  • Official Full Name

    MAP/microtubule affinity-regulating kinase 2

  • Overview

    Microtubule associated proteins regulate the stability of microtubules and control processes such as cell polarity/differentiation, neurite outgrowth, cell division and organelle trafficking. The MARK (MAP/microtubule affinity-regulating kinases) family (
  • Synonyms

    MARK2; MAP/microtubule affinity-regulating kinase 2; ELKL motif kinase , EMK1; serine/threonine-protein kinase MARK2; ELKL motif kinase 1; PAR 1; Par1b; protein serine/threonine kinase; Ser/Thr protein kinase PAR 1B; serine/threonine kinase; PAR1 homolog;

  • Recombinant Proteins
  • Cell & Tissue Lysates
  • Protein Pre-coupled Magnetic Beads
  • Human
  • Mouse
  • Rat
  • E.coli
  • HEK293
  • HEK293T
  • Insect (sf21)
  • Mammalian Cell
  • Sf9 Insect Cell
  • GST
  • His
  • His (Fc)
  • Avi
  • Myc
  • DDK
  • N/A
Species Cat.# Product name Source (Host) Tag Protein Length Price
Human MARK2-1057H Recombinant Human MAP/Microtubule Affinity-Regulating Kinase 2, GST-tagged Sf9 Insect Cell GST
Human MARK2-781H Recombinant Human MARK2 Protein, His-tagged E.coli His
Human MARK2-1060HCL Recombinant Human MARK2 cell lysate N/A
Human MARK2-3525H Recombinant Human MARK2 protein, His-tagged E.coli His 10-372 aa
Human MARK2-3270HF Active Recombinant Full Length Human MARK2 Protein, GST-tagged Insect (sf21) GST 1-745
Mouse MARK2-9568M Recombinant Mouse MARK2 Protein Mammalian Cell His
Mouse Mark2-3960M Recombinant Mouse Mark2 Protein, Myc/DDK-tagged HEK293T Myc/DDK
Mouse MARK2-5373M Recombinant Mouse MARK2 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Mouse MARK2-5373M-B Recombinant Mouse MARK2 Protein Pre-coupled Magnetic Beads HEK293
Rat MARK2-3589R Recombinant Rat MARK2 Protein Mammalian Cell His
Rat MARK2-3245R Recombinant Rat MARK2 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Rat MARK2-3245R-B Recombinant Rat MARK2 Protein Pre-coupled Magnetic Beads HEK293
  • Involved Pathway
  • Protein Function
  • Interacting Protein

MARK2 involved in several pathways and played different roles in them. We selected most pathways MARK2 participated on our site, such as LKB1 signaling events, Notch signaling pathway, Regulation of Microtubule Cytoskeleton, which may be useful for your reference. Also, other proteins which involved in the same pathway with MARK2 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name Pathway Related Protein
LKB1 signaling eventsMARK2;CTSD;SIK3;CDC37;MAP2;STK11IP;MARK4
Notch signaling pathwayDTX4;NOTCH4;RBPJ;HER12;RBPJA;DLL1;NOTCH2;DLL4;PSEN2
Regulation of Microtubule CytoskeletonMARK1;TESK2;TPPP;DPYSL2;MARK2;MAP1B;CFL2
TNF-alpha/NF-kB Signaling PathwayCOPS3;MCC;G3BP2;CRADD;DCAF7;RNF216;DDX3X;TANK;UNC5CL
Wnt Signaling Pathway NetPathPAX2;TCF4;ANKRD6;HIPK2;ROR2;MARK2;SALL1;NR5A1;CRYBB2

MARK2 has several biochemical functions, for example, ATP binding, lipid binding, magnesium ion binding. Some of the functions are cooperated with other proteins, some of the functions could acted by MARK2 itself. We selected most functions MARK2 had, and list some proteins which have the same functions with MARK2. You can find most of the proteins on our site.

Function Related Protein
ATP bindingTTLL6;VRK3;ERCC6L2;TAP1;PMS1;HK3;IRAK4;MYO18A;MYLK4
lipid bindingAPOL6;VCP;YBX2;CETP;CRABP1B;BPIFB4;FFAR1;LIPF;FABP7A
magnesium ion bindingPRKACB;THTPA;GCLC;HACL1;ENO1B;PGM5;HPRT1;PRPS1;IMPAD1
poly(A) RNA bindingFCF1;TNRC6B;UNK;UTP15;CCAR1;CS;RBM25;NOC2L;MRPL15
protein bindingH3F3B;AKAP13;RNF115;TBX24;CD48;ADD1;MAP2K6;MYL7;ACAD9
protein kinase activator activityDBF4B;STRADA;DAXX;TOM1L1;FGF13;MARK2;MT3;AGAP2;FAM58A
protein serine/threonine kinase activitySQSTM1;ACVR2AA;PRKAA2;PHKG1A;MAPK6;RPS6KB1B;ACVR2B;GRK7A;OXSR1A
tau-protein kinase activityMARK1;GSK3B;CDK5;MARK4;MARK2;PRKAA1;PHKG1;PHKG2;CSNK1D

MARK2 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with MARK2 here. Most of them are supplied by our site. Hope this information will be useful for your research of MARK2.

YWHAH; YWHAZ; MTCL1; MAPT

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