|Official Full Name||methyltransferase like 1|
|Background||This gene is similar in sequence to the S. cerevisiae YDL201w gene. The gene product contains a conserved S-adenosylmethionine-binding motif and is inactivated by phosphorylation. Alternative splice variants encoding different protein isoforms have been described for this gene. A pseudogene has been identified on chromosome X.|
|Synonyms||METTL1; methyltransferase like 1; C12orf1, methyltransferase like 1; tRNA (guanine-N(7)-)-methyltransferase; TRM8; C12orf1; D1075 like gene product; FLJ95748; Methyltransferase like protein 1; tRNA (guanine N(7) ) methyltransferase; tRNA(m7G46) methyltransferase; YDL201w; D1075-like gene product; methyltransferase-like 1; tRNA(m7G46)-methyltransferase; methyltransferase-like protein 1|
|Species||Cat.#||Product name||Source (Host)||Tag||Protein Length||Price|
METTL1 involved in several pathways and played different roles in them. We selected most pathways METTL1 participated on our site, such as Gene Expression, tRNA modification in the nucleus and cytosol, tRNA processing, which may be useful for your reference. Also, other proteins which involved in the same pathway with METTL1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
|Pathway Name||Pathway Related Protein|
|Gene Expression||NSUN2; TRMT11; ZNF484; ZNF383; ZNF287; ZNF100; NR1H3; TNKS1BP1; ZNF556; WHSC2|
|tRNA modification in the nucleus and cytosol||TRMT6; PUS7; CDKAL1; ALKBH8; OSGEP; LAGE3; NSUN2; PUS1; TPRKB; TRMT44|
|tRNA processing||LAGE3; TSEN15; TSEN2; POP7; RPP30; C22orf28; TRMT12; TPRKB; TRMT1; TYW1|
METTL1 has several biochemical functions, for example, protein binding, tRNA (guanine-N7-)-methyltransferase activity, contributes_to tRNA (guanine-N7-)-methyltransferase activity. Some of the functions are cooperated with other proteins, some of the functions could acted by METTL1 itself. We selected most functions METTL1 had, and list some proteins which have the same functions with METTL1. You can find most of the proteins on our site.
|protein binding||ATP2A2; FGF10; BFSP2; CDCA7L; ERGIC2; SPARC; PRDX3; HSPB6; SULT1C2; SSH1|
|tRNA (guanine-N7-)-methyltransferase activity||METTL1|
|contributes_to tRNA (guanine-N7-)-methyltransferase activity||WDR4; METTL1|
|tRNA binding||TRMT1L; RARS; FARS2; KARS; PSTK; FARSA; CTU1; IGHMBP2; MADD; SEPSECS|
METTL1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with METTL1 here. Most of them are supplied by our site. Hope this information will be useful for your research of METTL1.