mknk1
Share
  • Official Full Name
  • MAP kinase interacting serine/threonine kinase 1
  • Background
  • Mitogen-activated protein kinases (MAPKs) are activated by various extracellular signals and play crucial roles in regulating cell proliferation, differentiation, survival, and apoptosis (1). MAPK-interacting kinases (Mnks or MKNKs) are direct downstream
  • Synonyms
  • MKNK1; MAP kinase interacting serine/threonine kinase 1; MAP kinase-interacting serine/threonine-protein kinase 1; MNK1; MAPK signal-integrating kinase 1; MAP kinase signal-integrating kinase 1
Cat.#:MKNK1-5365HTag:GST
Source (Host):Insect cellSpecies:Human
Product nameRecombinant Human MKNK1 Protein, GST-tagged
+Inquiry
Cat.#:MKNK1-5366HTag:GST
Source (Host):Wheat GermSpecies:Human
Product nameRecombinant Human MKNK1 Protein, GST-tagged
+Inquiry
Cat.#:MKNK1-28176THTag:N/A
Source (Host):Species:Human
Product nameRecombinant Human MKNK1
+Inquiry
Cat.#:MKNK1-65HTag:Flag
Source (Host):Insect cellSpecies:Human
Product nameRecombinant Human MKNK1 protein, Flag-tagged, Biotinylated
+Inquiry
Cat.#:MKNK1-3696RTag:His
Source (Host):Mammalian CellsSpecies:Rat
Product nameRecombinant Rat MKNK1 Protein
+Inquiry
Cat.#:MKNK1-6476ZTag:His
Source (Host):Mammalian CellsSpecies:Zebrafish
Product nameRecombinant Zebrafish MKNK1
+Inquiry
Cat.#:MKNK1-519HTag:GST
Source (Host):Sf 9 Insect cellsSpecies:Human
Product nameRecombinant Human MKNK1, GST-tagged
+Inquiry
Cat.#:MKNK1-1061HTag:GST
Source (Host):Sf 9 Insect cellsSpecies:Human
Product nameRecombinant Human MAP Kinase Interacting Serine/Threonine Kinase 1, GST-tagged
+Inquiry
Cat.#:MKNK1-4303HCLTag:N/A
Source (Host):Species:Human
Product nameRecombinant Human MKNK1 293 Cell Lysate
+Inquiry

Involved Pathway

MKNK1 involved in several pathways and played different roles in them. We selected most pathways MKNK1 participated on our site, such as MAPK signaling pathway, HIF- signaling pathway, Insulin signaling pathway, which may be useful for your reference. Also, other proteins which involved in the same pathway with MKNK1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
Pathway Name
Pathway Related Protein
MAPK signaling pathway
PRKCA; Casp3; MAP2K7; HSPA8; MAP3K14; DUSP3; NFKB1; FGF4; HSP70L; GRB2B
HIF- signaling pathway
ENO3; PIK3CG; EIF4E1B; RBX1; HK2; NPPA; TLR4; PDK1; VEGFA; CAMK2D
Insulin signaling pathway
FBP2; AKT3A; FOXO1A; MAPK9; EIF4EA; HRASB; FLOT1A; PIK3CD; PIK3R1; CALM1B

Protein Function

MKNK1 has several biochemical functions, for example, ATP binding, calcium-dependent protein serine/threonine kinase activity, calmodulin binding. Some of the functions are cooperated with other proteins, some of the functions could acted by MKNK1 itself. We selected most functions MKNK1 had, and list some proteins which have the same functions with MKNK1. You can find most of the proteins on our site.
Function
Related Protein
Function ATP binding
Related Protein ATP2B1B; KIF20A; THG1L; ACTG2; MAPK12B; PEBP1; CDK16; SPEG; GSS; ACSM3
Function calcium-dependent protein serine/threonine kinase activity
Related Protein MKNK2B; MAPKAPK5; MAPKAPK2B; CAMK4; CAMK1GA; MKNK2A; CAMK1GB; MAPKAPK2A; MKNK2; DCX
Function calmodulin binding
Related Protein ASPM; NRGN; MKNK2; USP6; ITPKB; SRY; MARCKSA; TRPC2; PCDP1; ADCY3
Function calmodulin-dependent protein kinase activity
Related Protein ITPKA; MAPKAPK5; DAPK1; CAMK2B; MKNK1; CAMK1; CAMK2D2; MKNK2; PNCK; CAMK1G
Function protein binding
Related Protein ING2; CTNNB1; HCLS1; MGAT5B; TIMM23; FGFR3; PAM16; ERBB4; ACOT7; ZNF217
Function protein serine/threonine kinase activity
Related Protein ZNF143B; BMPR1AA; TLK2; NEK11; LMTK2; MAPK14B; STK35L; PAK6; EIF2AK4; PIK3CA

Interacting Protein

MKNK1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with MKNK1 here. Most of them are supplied by our site. Hope this information will be useful for your research of MKNK1.
MAPK14; PPP2CA; EIF4E; EIF4G1; PAK2; HGS; EIF4G3; DDAH2; HSP90AB1; UBE2D1; ATXN3; PRKDC; TNIP2; CREBBP