Recombinant Human MKNK1 Protein, GST-tagged

• Cat.No.: MKNK1-5366H
• Product Overview: Human MKNK1 full-length ORF ( AAH02755.1, 1 a.a. - 465 a.a.) recombinant protein with GST-tag at N-terminal.

Specification

• Description: This gene encodes a Ser/Thr protein kinase that interacts with, and is activated by ERK1 and p38 mitogen-activated protein kinases, and thus may play a role in the response to environmental stress and cytokines. This kinase may also regulate transcription by phosphorylating eIF4E via interaction with the C-terminal region of eIF4G. Alternatively spliced transcript variants have been noted for this gene. [provided by RefSeq, Jan 2012]
• Source: Wheat Germ
• Species: Human
• Tag: GST
• Molecular Mass: 76.89 kDa
• AA Sequence: MVSSQKLEKPIEMGSSEPLPIADGD RRRKKKRRGRATDSLPGKFEDMYKL TSELLGEGAYAKVQGAVSLQNGKEY AVKIIEKQAGHSRSRVFREVETLYQ CQRNKNILELIEFFEDDTRFYLVFE KLQGGSILAHIQKQKHFNEREASRV VRGVAAALDFLHTKDKVSLCHLGWS AMAPSGLTAAPTSLGSSDPPTSASQ VAGTTGIAHRDLKPENILCESPEKV SPVKICDFDLGSGMKLNNSCTPITT PELTTPCGSAEYMAPEVVEVFTDQA TFYDKRCDLWSLGVVLYIMLSGYPP FVGHCGADCGWDRGEVCRVCQNKLF ESIQEGKYEFPDKDWAHISSEAKDL ISKLLVRDAKQRLSAAQVLQHPWVQ GQAPEKGLPTPQVLQRNSSTMDLTL FAAEAIALNRLLSQHEENELAEEPE ALADGLCSMKLSPPCKSRLARRRAL AQAGRGEDRSPPTAL
• Applications: Enzyme-linked Immunoabsorbent Assay
  Western Blot (Recombinant protein)
  Antibody Production
  Protein Array
• Notes: Best use within three months from the date of receipt of this protein.
• Storage: Store at -80 centigrade. Aliquot to avoid repeated freezing and thawing.
• Storage Buffer: 50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.

Gene Information

• Gene Name: MKNK1 MAP kinase interacting serine/threonine kinase 1 [ Homo sapiens ]
• Official Symbol: MKNK1
• Synonyms: MKNK1; MAP kinase interacting serine/threonine kinase 1; MAP kinase-interacting serine/threonine-protein kinase 1; MNK1; MAPK signal-integrating kinase 1; MAP kinase signal-integrating kinase 1
• Gene ID: 8569
• mRNA Refseq: NM_001135553
• Protein Refseq: NP_001129025
• MIM: 606724
• UniProt ID: Q9BUB5