Recombinant Human MAP Kinase Interacting Serine/Threonine Kinase 1, GST-tagged

• Cat.No.: MKNK1-1061H
• Product Overview: Recombinant full-length human MKNK1 was expressed by baculovirus in Sf9 insect cells using an N-terminal GST tag.

Specification

• Species: Human
• Source: Sf9 Cells
• Tag: GST
• Description: MKNK1 (MAP kinase-interacting kinase 2) is a MAP kinase interacting serine/threonine kinase 1 that isolated by a novel expression screening method for identifying the protein kinase substrates. MKNK1 expressed in all tissues with the highest level of expression in skeletal muscle.
• Applications: Kinase Assay; Western Blot
• Molecular Weight: 92 kDa
• Expression System: Sf9 insect cells using baculovirus
• Form: Recombinant protein stored in 50 mM Tris-HCl, pH 7.5, 150 mM NaCl, 10 mM glutathione, 0.1 mM EDTA, 0.25 mM DTT, 0.1 mM PMSF, 25% glycerol.
• Specific Activity: 20 nmol/min/mg
• Purity: > 85%
• Concentration: 0.1 ug/ul
• Sequences: full-length
• Storage: Store product at -70oC. For optimal storage, aliquot target into smaller quantities after centrifugation and store at recommended temperature. For most favorable performance, avoid repeated handling and multiple freeze/thaw cycles.

Gene Information

• Gene Name: MKNK1 MAP kinase interacting serine/threonine kinase 1 [ Homo sapiens ]
• Official Symbol: MKNK1
• Synonyms: MKNK1; MAP kinase interacting serine/threonine kinase 1; MNK1; MKNK1; MAP kinase interacting kinase 1; EC 2.7.11.1; Mnk1; OTTHUMP00000009674; MAP kinase signal-integrating kinase 1; MAP kinase-interacting serine/threonine kinase 1
• Gene ID: 8569
• mRNA Refseq: NM_001135553
• Protein Refseq: NP_001129025
• MIM: 606724
• UniProt ID: Q9BUB5
• Chromosome Location: 1p33
• Pathway: Insulin signaling pathway; MAPK signaling pathway;IL-2 Signaling Pathway; Signaling mediated by p38-alpha and p38-beta; p38 MAPK Signaling Pathway
• Function: ATP binding; nucleotide binding; protein binding; protein serine/threonine kinase activity; transferase activity