mnd1
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  • Official Full Name
  • meiotic nuclear divisions 1 homolog (S. cerevisiae)
  • Background
  • The product of the MND1 gene associates with HOP2 (MIM 608665) to form a stable heterodimeric complex that binds DNA;and stimulates the recombinase activity of RAD51 (MIM 179617) and DMC1 (MIM 602721) (Chi et al., 2007 (PubMed;17639080)). Both the MND1 and HOP2 genes are indispensable for meiotic recombination.
  • Synonyms
  • MND1; meiotic nuclear divisions 1 homolog (S. cerevisiae); meiotic nuclear division protein 1 homolog; GAJ; 2610034E18Rik; AI591601; GAJ protein; Homolog of yeast MND1; Meiotic nuclear division 1, S. cerevisiae. homolog of; Meiotic nuclear divisions 1 homolog; MGC134110; RGD1309007
Cat.#:MND1-4669HTag:GST
Source (Host):Wheat GermSpecies:Human
Product nameRecombinant Human MND1 Protein, GST-tagged
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Cat.#:MND1-923HTag:GST
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human MND1, GST-tagged
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Cat.#:MND1-9934MTag:His
Source (Host):Mammalian CellsSpecies:Mouse
Product nameRecombinant Mouse MND1 Protein
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Cat.#:MND1-2796RTag:His
Source (Host):Mammalian CellsSpecies:Rhesus Macaque
Product nameRecombinant Rhesus monkey MND1 Protein, His-tagged
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Cat.#:MND1-4621CTag:His
Source (Host):Mammalian CellsSpecies:Chicken
Product nameRecombinant Chicken MND1
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Cat.#:MND1-1024ZTag:His
Source (Host):Mammalian CellsSpecies:Zebrafish
Product nameRecombinant Zebrafish MND1
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Cat.#:MND1-678HCLTag:N/A
Source (Host):Species:Human
Product nameRecombinant Human MND1 cell lysate
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Involved Pathway

MND1 involved in several pathways and played different roles in them. We selected most pathways MND1 participated on our site, such as Cell Cycle, Meiosis, Meiotic recombination, which may be useful for your reference. Also, other proteins which involved in the same pathway with MND1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
Pathway Name
Pathway Related Protein
Cell Cycle
GORASP2; E2F5; STIL; ANAPC1; MCM4; DULLARD; ATM; POT1A; PANE1; MIS18A
Meiosis
DMC1; TERF1; MND1; SUN1; STAG2; PSMC3IP; TERF2IP; SYCE1; SYCP2; DIDO1
Meiotic recombination
MSH4; SPO11; PSMC3IP; DMC1; TEX15; MND1; MSH5

Protein Function

MND1 has several biochemical functions, for example, DNA binding. Some of the functions are cooperated with other proteins, some of the functions could acted by MND1 itself. We selected most functions MND1 had, and list some proteins which have the same functions with MND1. You can find most of the proteins on our site.
Function
Related Protein
Function DNA binding
Related Protein DBN1; FOXB1A; ZBTB17; HIST1H2BP; SIX6; TIGD1; TTC4; SMAD6A; TRP63; ZNF669

Interacting Protein

MND1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with MND1 here. Most of them are supplied by our site. Hope this information will be useful for your research of MND1.
IK; PSMC3IP

MND1 Related Articles

Cho, NW; Dilley, RL; et al. Interchromosomal Homology Searches Drive Directional ALT Telomere Movement and Synapsis. CELL 159:108-121(2014).
Chan, YL; Brown, MS; et al. The Third Exon of the Budding Yeast Meiotic Recombination Gene HOP2 Is Required for Calcium-dependent and Recombinase Dmc1-specific Stimulation of Homologous Strand Assimilation. JOURNAL OF BIOLOGICAL CHEMISTRY 289:18076-18086(2014).