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MRPL48

Official Full Name

mitochondrial ribosomal protein L48
Overview

Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75% protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. This gene encodes a 39S subunit protein. A pseudogene corresponding to this gene is found on chromosome 6p.
Synonyms

MRPL48; mitochondrial ribosomal protein L48; 39S ribosomal protein L48, mitochondrial; CGI 118; 39S ribosomal protein L48 mitochondrial; FLJ17047; FLJ99260; HSPC290; L48mt; MGC13323; MRP L48; CGI-118; MRP-L48;

Type

Recombinant Proteins
Cell & Tissue Lysates

Species

Chicken
Human
Zebrafish

Source

E.coli
HEK293
In Vitro Cell Free System
Mammalian Cell
Wheat Germ

Tag

Species	Cat.#	Product name	Source (Host)	Tag	Protein Length	Price
Human	MRPL48-1011H	Recombinant Human MRPL48, GST-tagged	E.coli	GST	1-212aa	$319 / 25ug
Human	MRPL48-616H	Recombinant Human mitochondrial ribosomal protein L48, His-tagged	E.coli	His		Inquiry
Human	MRPL48-147H	Recombinant Human MRPL48, His-tagged	HEK293	His		Inquiry
Human	MRPL48-4161HCL	Recombinant Human MRPL48 293 Cell Lysate	HEK293	N/A		Inquiry
Human	MRPL48-6432HF	Recombinant Full Length Human MRPL48 Protein, GST-tagged	In Vitro Cell Free System	GST	212 amino acids	Inquiry
Human	MRPL48-5591H	Recombinant Human MRPL48 Protein, GST-tagged	Wheat Germ	GST		Inquiry
Zebrafish	MRPL48-2087Z	Recombinant Zebrafish MRPL48	Mammalian Cell	His		Inquiry
Chicken	MRPL48-2219C	Recombinant Chicken MRPL48	Mammalian Cell	His		Inquiry

Involved Pathway
Protein Function
Interacting Protein

MRPL48 involved in several pathways and played different roles in them. We selected most pathways MRPL48 participated on our site, such as Mitochondrial translation, Mitochondrial translation elongation, Mitochondrial translation initiation, which may be useful for your reference. Also, other proteins which involved in the same pathway with MRPL48 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name	Pathway Related Protein
Mitochondrial translation	MRPL54;MRPL53;MRPS35;MRRF;MRPS24;PTCD3;MRPS34;MRPS30;MRPL52
Mitochondrial translation elongation	ICT1;AURKAIP1;MRPS36;MRPL42;MRPL41;MRPS28;PTCD3;MRPL46;MRPS35
Mitochondrial translation initiation	CHCHD1;MRPL44;MRPL45;MRPL46;MRPL50;AURKAIP1;MRPS36;MRPS33;MTIF3
Mitochondrial translation termination	MRPS31;MRPS35;MRPS30;MRPL52;MRPL38;MRPL51;MRPL39;PTCD3;MRPS36
Organelle biogenesis and maintenance	DYNLL2A;MRPL54;POLG2;MRPL40;EXOC8;BBS1;MRPL39;IFT46;EXOC3

MRPL48 has several biochemical functions, for example, protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by MRPL48 itself. We selected most functions MRPL48 had, and list some proteins which have the same functions with MRPL48. You can find most of the proteins on our site.

Function	Related Protein
protein binding	KRTAP10-5;VPS28;KCNMB4;CCDC108;MEP1A;CUL1;PRKAR2A;ATXN3;ATP6V1D

MRPL48 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with MRPL48 here. Most of them are supplied by our site. Hope this information will be useful for your research of MRPL48.

Kifc5b; ssrna_ag; AP4M1; Shoc2; SLC25A5; Eif3a; RPL10; CRK; YBX1; Cbx1; ICT1; Papss1; Rpl35; MRPL50; MRPL9; Bcas2; EXOSC4