nr1h3
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  • Official Full Name
  • NR1H3 nuclear receptor subfamily 1, group H, member 3
  • Synonyms
  • NR1H3; nuclear receptor subfamily 1, group H, member 3; oxysterols receptor LXR-alpha; liver X receptor alpha; LXR a; RLD 1; liver X nuclear receptor alpha variant 1; LXRA; LXR-a; RLD-1;
Cat.#:NR1H3-1377HTag:His|SUMO
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human NR1H3 Protein, His/SUMO-tagged
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Cat.#:NR1H3-159HTag:His
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human NR1H3 Protein, His-tagged
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Cat.#:NR1H3-6070HTag:GST
Source (Host):Wheat GermSpecies:Human
Product nameRecombinant Human NR1H3 Protein, GST-tagged
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Cat.#:Nr1h3-160MTag:His
Source (Host):E. coliSpecies:Mouse
Product nameRecombinant Mouse Nr1h3 Protein, His-tagged
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Cat.#:NR1H3-158BTag:His
Source (Host):E. coliSpecies:Bovine
Product nameRecombinant Bovine NR1H3 Protein, His-tagged
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Cat.#:NR1H3-1054HTag:N/A
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human NR1H3
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Cat.#:NR1H3-1055HTag:GST
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human NR1H3, GST-tagged
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Cat.#:NR1H3-1056HTag:N/A
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human NR1H3, LB Domain
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Cat.#:NR1H3-1057HTag:GST
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human NR1H3, LB Domain, GST-tagged
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Cat.#:NR1H3-1058HTag:GST
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human NR1H3, 1-182aa, GST-tagged
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Cat.#:NR1H3-116HTag:GST
Source (Host):Sf 9 Insect cellsSpecies:Human
Product nameRecombinant Human NR1H3, GST-tagged
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Cat.#:NR1H3-1355HTag:His
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human NR1H3, His-tagged
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Cat.#:NR1H3-2504HTag:His
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human NR1H3, His-tagged
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Cat.#:NR1H3-593HTag:His
Source (Host):Mammalian CellsSpecies:Human
Product nameRecombinant Human NR1H3
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Cat.#:NR1H3-6111CTag:His
Source (Host):Mammalian CellsSpecies:Chicken
Product nameRecombinant Chicken NR1H3
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Cat.#:NR1H3-2328ZTag:His
Source (Host):Mammalian CellsSpecies:Zebrafish
Product nameRecombinant Zebrafish NR1H3
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Cat.#:NR1H3-3720HCLTag:N/A
Source (Host):Species:Human
Product nameRecombinant Human NR1H3 293 Cell Lysate
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Involved Pathway

NR1H3 involved in several pathways and played different roles in them. We selected most pathways NR1H3 participated on our site, such as Adipogenesis, Gene Expression, Generic Transcription Pathway, which may be useful for your reference. Also, other proteins which involved in the same pathway with NR1H3 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
Pathway Name
Pathway Related Protein
Adipogenesis
DVL1; RETN; FOXC2; HMGA1; KLF7A; CDKN1A; KLF6; SMAD3B; MEF2AA; EPAS1B
Gene Expression
PHF19; COX7C; CTDP1; ZNF615; EIF4B; ZNF599; ESR2A; RRAGB; BRF1; RPP30
Generic Transcription Pathway
NR2F6; ZNF560; HELZ2; ZNF43; FAM36A; ZIM3; ZNF773; MED20; NR2F1; ZIM2
Hepatitis C
MAPK3; TRAF3; PPP2R2B; EIF2AK4; IFNA1; TRADD; PIK3R5; IFNA12; IFNA21; IFNA4
Insulin resistance
INSB; PCK2; PRKAA2; NFKBIAB; RELA; SLC2A1; SOCS3B; PRKAB2; PPP1R3C; CREB3L3
Non-alcoholic fatty liver disease (NAFLD)
ITCH; PRKAA1; RAC1; NDUFB9; IKBKB; XBP1; UQCRC1; FAS; NDUFB8; COX7B2
Nuclear Receptor transcription pathway
ESRRG; NR2F6A; RARG; NR2C1; NR1D2; RXRBB; NR5A1; NR2C2; RORAA; ESRRGA
Nuclear Receptors
NR5A1; NR1I3; NR4A2A; RARGA; NR1I2; NR2F6; NR2F1; RARGB; ROR1; NR2E1

Protein Function

NR1H3 has several biochemical functions, for example, DNA binding, RNA polymerase II transcription factor activity, ligand-activated sequence-specific DNA binding, cholesterol binding. Some of the functions are cooperated with other proteins, some of the functions could acted by NR1H3 itself. We selected most functions NR1H3 had, and list some proteins which have the same functions with NR1H3. You can find most of the proteins on our site.
Function
Related Protein
Function DNA binding
Related Protein TFIP11; POLG; MYCLB; TMPO; ZFML; RREB1; TWIST2; SSRP1A; DERL3; MTF2
Function RNA polymerase II transcription factor activity, ligand-activated sequence-specific DNA binding
Related Protein NR1H4; ESR2; RORCB; NR1H2; NR2F1A; NR1I3; NR1D2; RORCA; PPARD; NR2F1B
Function cholesterol binding
Related Protein TSPO2; STARD6; APOA2; APOF; OSBPL2; APOA4B.2; ANXA6; PROM2; OSBP2; PTCH1
Function protein binding
Related Protein SMG5; ANXA4; MARVELD2; MBP; CD200; HBP1; SUGP1; NCKIPSD; SDHA; RIPK1
Function sequence-specific DNA binding
Related Protein LHX2B; NR1H4; PRDM5; POU2F1B; FOXO3; UNCX4.1; NR1H5; ISL2A; NFE2L2B; CSRNP1
Function steroid hormone receptor activity
Related Protein ESRRA; RORC; PAQR7A; ESRRG; NR1H2; NR1D2A; NR5A1A; ESRRGB; VDRB; NR2F6B
Function sterol response element binding
Related Protein NR1H3; SREBF1
Function transcription coactivator activity
Related Protein CD3D; LPIN1; NFKB2; JUPA; KAT2B; LPIN3; PIAS2; MED23; MTF1; RAN
Function transcription regulatory region DNA binding
Related Protein SALL1; REST; RBBP5; HINFP; KLF1; FOXC2; SOX7; H2AFY2; CBX4; CARM1
Function contributes_to transcription regulatory region DNA binding
Related Protein HAND1; ATF4; NR1H3; TAF1; NFYB; NFYC; TCF3; NFYA; RXRA; HDAC4
Function zinc ion binding
Related Protein RBBP6; RORAB; NR4A3; ZNRD1; NR4A2B; PHF13; ZBTB32; PRKCBB; TK1; TRIM35-31

Interacting Protein

NR1H3 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with NR1H3 here. Most of them are supplied by our site. Hope this information will be useful for your research of NR1H3.
RXRG; NCOA1

NR1H3 Related Articles

Constantinopoulos, P; Michalaki, M; et al. Cortisol in tissue and systemic level as a contributing factor to the development of metabolic syndrome in severely obese patients. EUROPEAN JOURNAL OF ENDOCRINOLOGY 172:-(2015).
Xia, X; Qu, B; et al. Analyzing time-series microarray data reveals key genes in spinal cord injury. MOLECULAR BIOLOGY REPORTS 41:6827-6835(2014).