nr1h3
Share
  • Official Full Name
  • NR1H3 nuclear receptor subfamily 1, group H, member 3
  • Synonyms
  • NR1H3; nuclear receptor subfamily 1, group H, member 3; oxysterols receptor LXR-alpha; liver X receptor alpha; LXR a; RLD 1; liver X nuclear receptor alpha variant 1; LXRA; LXR-a; RLD-1;
Cat.#:NR1H3-1377HTag:His/SUMO
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human NR1H3 Protein, His/SUMO-tagged
+Inquiry
Cat.#:NR1H3-159HTag:His
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human NR1H3 Protein, His-tagged
+Inquiry
Cat.#:NR1H3-6070HTag:GST
Source (Host):Wheat GermSpecies:Human
Product nameRecombinant Human NR1H3 Protein, GST-tagged
+Inquiry
Cat.#:Nr1h3-160MTag:His
Source (Host):E. coliSpecies:Mouse
Product nameRecombinant Mouse Nr1h3 Protein, His-tagged
+Inquiry
Cat.#:NR1H3-158BTag:His
Source (Host):E. coliSpecies:Bovine
Product nameRecombinant Bovine NR1H3 Protein, His-tagged
+Inquiry
Cat.#:NR1H3-1054HTag:N/A
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human NR1H3
+Inquiry
Cat.#:NR1H3-1055HTag:GST
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human NR1H3, GST-tagged
+Inquiry
Cat.#:NR1H3-1056HTag:N/A
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human NR1H3, LB Domain
+Inquiry
Cat.#:NR1H3-1057HTag:GST
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human NR1H3, LB Domain, GST-tagged
+Inquiry
Cat.#:NR1H3-1058HTag:GST
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human NR1H3, 1-182aa, GST-tagged
+Inquiry
Cat.#:NR1H3-116HTag:GST
Source (Host):Sf 9 Insect cellsSpecies:Human
Product nameRecombinant Human NR1H3, GST-tagged
+Inquiry
Cat.#:NR1H3-1355HTag:His
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human NR1H3, His-tagged
+Inquiry
Cat.#:NR1H3-2504HTag:His
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human NR1H3, His-tagged
+Inquiry
Cat.#:NR1H3-593HTag:His
Source (Host):Mammalian CellsSpecies:Human
Product nameRecombinant Human NR1H3
+Inquiry
Cat.#:NR1H3-6111CTag:His
Source (Host):Mammalian CellsSpecies:Chicken
Product nameRecombinant Chicken NR1H3
+Inquiry
Cat.#:NR1H3-2328ZTag:His
Source (Host):Mammalian CellsSpecies:Zebrafish
Product nameRecombinant Zebrafish NR1H3
+Inquiry
Cat.#:NR1H3-3720HCLTag:
Source (Host):Species:Human
Product nameRecombinant Human NR1H3 293 Cell Lysate
+Inquiry

Involved Pathway

NR1H3 involved in several pathways and played different roles in them. We selected most pathways NR1H3 participated on our site, such as Adipogenesis, Gene Expression, Generic Transcription Pathway, which may be useful for your reference. Also, other proteins which involved in the same pathway with NR1H3 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
Pathway Name
Pathway Related Protein
Adipogenesis
CNTFR; CEBPA; PIANP; GADD45A; CFD; DLK1; RORAA; KLF5; SMAD3B; BSCL2
Gene Expression
ZIM2; DNMT3A; XPOT; ZNF266; ZNF333; ZNF543; POP4; APOBEC1; MED10; COX7C
Generic Transcription Pathway
ARHGEF38; MED8; NR1I3; NR5A1A; ZNF529; ZNF34; RARAB; NRBF2; ZNF573; ESRRG
Hepatitis C
CLDN6; PIK3CB; Ifna15; IFNA8; MAPK10; CLDN1; AKT1; DDX58; CD81; TNFRSF1A
Insulin resistance
STAT3; PTPRFB; CREB3L3L; CRTC2; PPP1R3D; PIK3CG; GFPT2; MAPK10; PRKCB; PTENA
Non-alcoholic fatty liver disease (NAFLD)
TGFB1; PIK3R5; PRKAA2; NDUFV1; BID; IL6R; PRKAG3; FAS; XBP1; NDUFB11
Nuclear Receptor transcription pathway
NR2F6A; NR2F1; NR2F1A; NR1H3; NRBP1; VDRB; NR6A1; NR6A1A; NRBF2; NR1D2
Nuclear Receptors
NR4A2A; RORAA; RARGB; RARG; NR2C2; NR2E1; NR1H3; ROR1; NR2F6; NR0B1

Protein Function

NR1H3 has several biochemical functions, for example, DNA binding, RNA polymerase II transcription factor activity, ligand-activated sequence-specific DNA binding, cholesterol binding. Some of the functions are cooperated with other proteins, some of the functions could acted by NR1H3 itself. We selected most functions NR1H3 had, and list some proteins which have the same functions with NR1H3. You can find most of the proteins on our site.
Function
Related Protein
Function DNA binding
Related Protein GLIS2; STRA13; TNP1; NEUROD6; DUX3; ASCL1; LIG1; BRIP1; HIST1H2B7; MSH2
Function RNA polymerase II transcription factor activity, ligand-activated sequence-specific DNA binding
Related Protein PPARA; NR5A1A; NR4A2B; NR2F1; NR2F6; NR5A1B; STAT3; NR6A1; RORB; PPARAA
Function cholesterol binding
Related Protein APOA1A; ANXA6; STARD3; NR1H3; OSBPL10; SOAT1; OSBPL1A; APOF; TSPO2; APOEB
Function protein binding
Related Protein ASAP2; GFAP; TGFB2; EXO1; GMPPB; SCAND1; MED12; MIEF1; ID3; SPSB4
Function sequence-specific DNA binding
Related Protein SOX2; FOXK2; CTCFL; MAFBA; HOXC13B; RXRAA; SIX4; ZNF263; NR4A1; FEV
Function steroid hormone receptor activity
Related Protein NR2F1B; RORC; RARAB; PGRMC2; RXRGB; OR51E2; PAQR8; NR3C2; NR2F2; RORB
Function sterol response element binding
Related Protein SREBF1; NR1H3
Function transcription coactivator activity
Related Protein PDLIM1; UTF1; TAF11; CITED1; SUB1B; NPM1; DDX17; NFYC; NCOA1; MAML1
Function transcription regulatory region DNA binding
Related Protein BCL11B; TRP53; HNF1A; OVOL2; XRCC5; SMAD6; SFPQ; SMARCA2; WNT1; HIVEP2A
Function contributes_to transcription regulatory region DNA binding
Related Protein NFYB; TCF12; ATF4; HAND1; HDAC4; HDAC5; TAF1; NFYC; TCF3; NR1H3
Function zinc ion binding
Related Protein C6AST1; TRIM2A; ESR1; RXRGB; LMCD1; RECQL4; ZFP330; KDM7AB; ADAMTS1; DNAJC21

Interacting Protein

NR1H3 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with NR1H3 here. Most of them are supplied by our site. Hope this information will be useful for your research of NR1H3.
RXRG; NCOA1

NR1H3 Related Articles

Constantinopoulos, P; Michalaki, M; et al. Cortisol in tissue and systemic level as a contributing factor to the development of metabolic syndrome in severely obese patients. EUROPEAN JOURNAL OF ENDOCRINOLOGY 172:-(2015).
Xia, X; Qu, B; et al. Analyzing time-series microarray data reveals key genes in spinal cord injury. MOLECULAR BIOLOGY REPORTS 41:6827-6835(2014).