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NR1H3

  • Official Full Name

    NR1H3 nuclear receptor subfamily 1, group H, member 3

  • Synonyms

    NR1H3; nuclear receptor subfamily 1, group H, member 3; oxysterols receptor LXR-alpha; liver X receptor alpha; LXR a; RLD 1; liver X nuclear receptor alpha variant 1; LXRA; LXR-a; RLD-1;

  • Recombinant Proteins
  • Cell & Tissue Lysates
  • Protein Pre-coupled Magnetic Beads
  • Bovine
  • Chicken
  • Human
  • Mouse
  • Zebrafish
  • E.coli
  • HEK293
  • HEK293T
  • In Vitro Cell Free System
  • Mammalian Cell
  • Mammalian cells
  • Sf9 Insect Cell
  • Wheat Germ
  • C
  • Myc
  • DDK
  • Flag
  • GST
  • His
  • His (Fc)
  • Avi
  • His|SUMO
  • N/A
  • No tag
Species Cat.# Product name Source (Host) Tag Protein Length Price
Human NR1H3-1058H Active Recombinant Human NR1H3, 1-182aa, GST-tagged E.coli GST
Human NR1H3-1056H Active Recombinant Human NR1H3, LB Domain E.coli N/A
Human NR1H3-2504H Active Recombinant Human NR1H3, His-tagged E.coli His
Human NR1H3-1054H Active Recombinant Human NR1H3 E.coli N/A
Human NR1H3-1055H Active Recombinant Human NR1H3, GST-tagged E.coli GST
Human NR1H3-1057H Active Recombinant Human NR1H3, LB Domain, GST-tagged E.coli GST
Human NR1H3-593H Recombinant Human NR1H3 Mammalian Cell His
Human NR1H3-116H Recombinant Human NR1H3, GST-tagged Sf9 Insect Cell GST
Human NR1H3-1377H Recombinant Human NR1H3 Protein, His/SUMO-tagged E.coli His/SUMO Met46-Glu387
Human NR1H3-1355H Recombinant Human NR1H3, His-tagged E.coli His 104-402aa
Human NR1H3-3720HCL Recombinant Human NR1H3 293 Cell Lysate HEK293 N/A
Human NR1H3-6070H Recombinant Human NR1H3 Protein, GST-tagged Wheat Germ GST
Human NR1H3-159H Recombinant Human NR1H3 Protein, His-tagged E.coli His Asn95~Lys434
Human NR1H3-1536H Recombinant Human NR1H3 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Human NR1H3-208H Recombinant Human NR1H3 Protein, MYC/DDK-tagged, C13 and N15-labeled HEK293 C-Myc/DDK
Human NR1H3-6699HF Recombinant Full Length Human NR1H3 Protein, GST-tagged In Vitro Cell Free System GST 387 amino acids
Human NR1H3-1353H Recombinant Human NR1H3 protein, His&Myc-tagged E.coli His&Myc 1-402aa
Human NR1H3-464HFL Active Recombinant Full Length Human NR1H3 Protein, C-Flag-tagged Mammalian cells Flag
Human NR1H3-0779H Recombinant Human NR1H3 Protein (Q182-E447), Tag Free E.coli No tag Q182-E447
Human NR1H3-0780H Recombinant Human NR1H3 Protein (Q182-E447), His tagged E.coli His Q182-E447
Human NR1H3-1536H-B Recombinant Human NR1H3 Protein Pre-coupled Magnetic Beads HEK293
Human NR1H3-3862H Recombinant Human NR1H3 Protein (Asn95-Lys434), His tagged E.coli His Asn95-Lys434
Mouse Nr1h3-4486M Recombinant Mouse Nr1h3 Protein, Myc/DDK-tagged HEK293T Myc/DDK
Mouse Nr1h3-160M Recombinant Mouse Nr1h3 Protein, His-tagged E.coli His Asn93~Lys432
Bovine NR1H3-158B Recombinant Bovine NR1H3 Protein, His-tagged E.coli His Asn95~Lys434
Zebrafish NR1H3-2328Z Recombinant Zebrafish NR1H3 Mammalian Cell His
Chicken NR1H3-6111C Recombinant Chicken NR1H3 Mammalian Cell His
  • Involved Pathway
  • Protein Function
  • Interacting Protein
  • NR1H3 Related Articles
  • NR1H3 Related Research Area

NR1H3 involved in several pathways and played different roles in them. We selected most pathways NR1H3 participated on our site, such as Adipogenesis, Gene Expression, Generic Transcription Pathway, which may be useful for your reference. Also, other proteins which involved in the same pathway with NR1H3 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name Pathway Related Protein
AdipogenesisGATA2;GDF10;NAMPT;CEBPD;KLF7A;KLF6A;GADD45A;DVL1;NR2F1
Gene ExpressionZNF383;DCP1B;TYW3;ZBTB8OS;BARHL1;HNRNPD;FARSB;ZCRB1;CCNT2B
Generic Transcription PathwayZNF554;ZNF713;ZNF274;ZNF562;ZNF256;ZNF461;MED10;NR2C1;ZNF688
Hepatitis CCLDN3;CLDN15;CLDN17;SCARB1;PIK3R1;RELA;CLDN5;LDLR;SOS1
Insulin resistanceNFKBIAB;SOCS3B;RPS6KA1;OGT;SLC2A1A;PRKAB1A;ACACB;PTPN11A;CD36
Non-alcoholic fatty liver disease (NAFLD)NDUFC1;PRKAB2;PRKAG2;SDHD;COX7A2;NDUFA12;MAP3K5;COX7A1;COX8C
Nuclear Receptor transcription pathwayVDRB;NR2C2AP;NR1I2;NR2C1;NR6A1;NR0B2A;NR0B1;RARAA;ESR2B
Nuclear ReceptorsNR4A2A;NR1H3;NR2F1;NR2F6;RARG;NR0B1;NR2F2;NR2F1A;NR5A1

NR1H3 has several biochemical functions, for example, DNA binding, RNA polymerase II transcription factor activity, ligand-activated sequence-specific DNA binding, cholesterol binding. Some of the functions are cooperated with other proteins, some of the functions could acted by NR1H3 itself. We selected most functions NR1H3 had, and list some proteins which have the same functions with NR1H3. You can find most of the proteins on our site.

Function Related Protein
DNA bindingZNF560;ATXN1L;NKX2.2B;FLI1A;ZBTB5;KDM5BA;SYCP3;ZBTB24;TTC4
RNA polymerase II transcription factor activity, ligand-activated sequence-specific DNA bindingNR6A1;AHR2;NR5A1B;NR2F2;PPARA;NR4A2B;ESRRA;NR2F1B;NR2F6B
cholesterol bindingAPOA4B.2;ERLIN1;APOC3;OSBP2;APOEA;OSBPL2;OSBPL8;OSBPL3;CYP11A1
protein bindingSERP1;RAPGEF4;GSTA4;ZRSR2;CD6;IFT172;USH2A;FABP2;ASF1A
sequence-specific DNA bindingZNF394;EGR1;PAX2A;ATF4B1;HOXD1;GBX1;PPARAB;HOXB2A;NKX2.1
steroid hormone receptor activityNR1D2;ESRRA;NR5A1A;NR5A1;NR6A1;NR2F5;NR4A2B;NR5A5;NR0B1
sterol response element bindingNR1H3;SREBF1
transcription coactivator activityHIF3A;RNF20;ZSCAN1;CTBP2;NFE2;RB1;ABT1;SUPT3H;DDX17
transcription regulatory region DNA bindingFOXM1;HOXA13;HIVEP3;TCF7;TRP63;CTCFL;BCL11B;ZFHX3;CREB3L1
contributes_to transcription regulatory region DNA bindingNFYA;ATF4;TCF12;HDAC5;TAF1;HAND1;TCF3;RXRA;HDAC4
zinc ion bindingLMCD1;LHX2B;ZDHHC14;LHX9;NR4A2A;KDM5BB;S100A6;MAN2B1;MMP1

NR1H3 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with NR1H3 here. Most of them are supplied by our site. Hope this information will be useful for your research of NR1H3.

RXRG; NCOA1

Constantinopoulos, P; Michalaki, M; et al. Cortisol in tissue and systemic level as a contributing factor to the development of metabolic syndrome in severely obese patients. EUROPEAN JOURNAL OF ENDOCRINOLOGY 172:-(2015).
Xia, X; Qu, B; et al. Analyzing time-series microarray data reveals key genes in spinal cord injury. MOLECULAR BIOLOGY REPORTS 41:6827-6835(2014).
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