Recombinant Full Length Human NR1H3 Protein, GST-tagged
Cat.No. : | NR1H3-6699HF |
Product Overview : | Human NR1H3 full-length ORF ( AAH08819, 1 a.a. - 387 a.a.) recombinant protein with GST-tag at N-terminal. |
- Specification
- Gene Information
- Related Products
Description : | The protein encoded by this gene belongs to the NR1 subfamily of the nuclear receptor superfamily. The NR1 family members are key regulators of macrophage function, controlling transcriptional programs involved in lipid homeostasis and inflammation. This protein is highly expressed in visceral organs, including liver, kidney and intestine. It forms a heterodimer with retinoid X receptor (RXR), and regulates expression of target genes containing retinoid response elements. Studies in mice lacking this gene suggest that it may play an important role in the regulation of cholesterol homeostasis. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Oct 2011] |
Source : | In Vitro Cell Free System |
Species : | Human |
Tag : | GST |
Molecular Mass : | 68.31 kDa |
Protein Length : | 387 amino acids |
AA Sequence : | MSLWLGAPVPDIPPDSAVELWKPGA QDASSQAQGGSSCILREEARMPHSA GGTAGVGLEAAEPTALLTRAEPPSE PTEIRPQKRKKGPAPKMLGNELCSV CGDKASGFHYNVLSCEGCKGFFRRS VIKGAHYICHSGGHCPMDTYMRRKC QECRLRKCRQAGMREECVLSEEQIR LKKLKRQEEEQAHATSLPPRASSPP QILPQLSPEQLGMIEKLVAAQQQCN RRSFSDRLRVTVMLLETSRRYNPGS ESITFLKDFSYNREDFAKAGLQVEF INPIFEFSRAMNELQLNDAEFALLI AISIFSADRPNVQDQLQVERLQHTY VEALHAYVSIHHPHDRLMFPRMLMK LVSLRTLSSVHSEQVFALRLQDKKL PPLLSEIWDVHE |
Applications : | Enzyme-linked Immunoabsorbent Assay Western Blot (Recombinant protein) Antibody Production Protein Array |
Notes : | Best use within three months from the date of receipt of this protein. |
Storage : | Store at -80 centigrade. Aliquot to avoid repeated freezing and thawing. |
Storage Buffer : | 50 mM Tris-HCl, 10 mM reduced Glutathione, pH=8.0 in the elution buffer. |
Gene Name : | NR1H3 nuclear receptor subfamily 1, group H, member 3 [ Homo sapiens ] |
Official Symbol : | NR1H3 |
Synonyms : | NR1H3; nuclear receptor subfamily 1, group H, member 3; oxysterols receptor LXR-alpha; liver X receptor alpha; LXR a; RLD 1; liver X nuclear receptor alpha variant 1; LXRA; LXR-a; RLD-1; |
Gene ID : | 10062 |
mRNA Refseq : | NM_001130101 |
Protein Refseq : | NP_001123573 |
MIM : | 602423 |
UniProt ID : | Q13133 |
Products Types
◆ Recombinant Protein | ||
NR1H3-0779H | Recombinant Human NR1H3 Protein (Q182-E447), Tag Free | +Inquiry |
NR1H3-0780H | Recombinant Human NR1H3 Protein (Q182-E447), His tagged | +Inquiry |
Nr1h3-160M | Recombinant Mouse Nr1h3 Protein, His-tagged | +Inquiry |
NR1H3-208H | Recombinant Human NR1H3 Protein, MYC/DDK-tagged, C13 and N15-labeled | +Inquiry |
NR1H3-6070H | Recombinant Human NR1H3 Protein, GST-tagged | +Inquiry |
◆ Lysates | ||
NR1H3-3720HCL | Recombinant Human NR1H3 293 Cell Lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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