nudt5
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  • Official Full Name
  • nudix (nucleoside diphosphate linked moiety X)-type motif 5
  • Background
  • Nudix hydrolases, such as NUDT5, eliminate toxic nucleotide derivatives from the cell and regulate the levels of;important signaling nucleotides and their metabolites (McLennan, 1999 (PubMed 10373642)).
  • Synonyms
  • NUDT5; nudix (nucleoside diphosphate linked moiety X)-type motif 5; ADP-sugar pyrophosphatase; hYSAH1; YSA1H; ADP sugar pyrophosphatase; hYSAH 1; Nucleoside diphosphate linked moiety X motif 5; Nucleoside diphosphate linked moiety X type motif 5; Nucleoside diphosphate-linked moiety X motif 5; Nudix (nucleoside diphosphate linked moiety X) type motif 5; Nudix motif 5; Nudix type motif 5; NUDT 5; NUDT5_HUMAN; YSA1; OTTHUMP00000019112; OTTHUMP00000019113; OTTHUMP00000019114; OTTHUMP00000019116; OTTHUMP00000019117; nucleoside diphosphate linked moiety X-type motif 5
Cat.#:NUDT5-153HTag:GST
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human NUDT5 Protein, GST-tagged
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Cat.#:NUDT5-154HTag:His
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human NUDT5 Protein, His-tagged
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Cat.#:NUDT5-213HTag:AVI
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human NUDT5, His tagged
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Cat.#:NUDT5-770HTag:His
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human NUDT5, His-tagged
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Cat.#:NUDT5-10976MTag:His
Source (Host):Mammalian CellsSpecies:Mouse
Product nameRecombinant Mouse NUDT5 Protein
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Cat.#:NUDT5-4120RTag:His
Source (Host):Mammalian CellsSpecies:Rat
Product nameRecombinant Rat NUDT5 Protein
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Cat.#:NUDT5-3130RTag:His
Source (Host):Mammalian CellsSpecies:Rhesus Macaque
Product nameRecombinant Rhesus monkey NUDT5 Protein, His-tagged
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Cat.#:NUDT5-318ZTag:His
Source (Host):Mammalian CellsSpecies:Zebrafish
Product nameRecombinant Zebrafish NUDT5
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Cat.#:NUDT5-3643HCLTag:N/A
Source (Host):Species:Human
Product nameRecombinant Human NUDT5 293 Cell Lysate
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Involved Pathway

NUDT5 involved in several pathways and played different roles in them. We selected most pathways NUDT5 participated on our site, such as Metabolism, Metabolism of nucleotides, Phosphate bond hydrolysis by NUDT proteins, which may be useful for your reference. Also, other proteins which involved in the same pathway with NUDT5 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
Pathway Name
Pathway Related Protein
Metabolism
GPAT2; ACY3; NAGS; MED9; ACOT10; SLC25A2; HELZ2; CHAT; NHLRC1; CYP8B2
Metabolism of nucleotides
GRX2; ITPA; DPYS; DHODH; UPP2; ADAL; ADSL; DTYMK; AK7; TYMP
Phosphate bond hydrolysis by NUDT proteins
NUDT18; NUDT5; NUDT16; NUDT15; NUDT1
Purine metabolism
ENTPD5; NT5C2A; RRM1; NT5C3L; PDE4B; PDE10A; NT5C1AA; IMPDH1B; ADK; PNP5A

Protein Function

NUDT5 has several biochemical functions, for example, ADP-ribose diphosphatase activity, ADP-sugar diphosphatase activity, NOT m7G(5)pppN diphosphatase activity. Some of the functions are cooperated with other proteins, some of the functions could acted by NUDT5 itself. We selected most functions NUDT5 had, and list some proteins which have the same functions with NUDT5. You can find most of the proteins on our site.
Function
Related Protein
Function ADP-ribose diphosphatase activity
Related Protein ADPRM; TRPM2; NUDT5; NUDT9; NUDT14
Function ADP-sugar diphosphatase activity
Related Protein NUDT9; NUDT5
Function NOT m7G(5)pppN diphosphatase activity
Related Protein NUDT16L1; NUDT7; NUDT5; NUDT1; NUDT4
Function magnesium ion binding
Related Protein ENO1; ENOSF1; ENDOV; ITPK1; CIB4; GLUL; GTPBP10; ZAK; PTENB; NUDT18
Function nucleoside-diphosphatase activity
Related Protein NUDT5; ENTPD3; ENTPD8; ENTPD1
Function snoRNA binding
Related Protein WDR3; NUDT1; NUDT7; NOP56; NUDT16; NOP14; IMP3; IMP4; PWP2H; NHP2

Interacting Protein

NUDT5 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with NUDT5 here. Most of them are supplied by our site. Hope this information will be useful for your research of NUDT5.
Mad2l1; GH1; MCC; HLA-B; EIF6; IKBKE; FTSJ1; PRKAB1; TRAF6; MCM3AP; NUDT3; MAPK6; q8ckd5_yerpe; HSPB9; MAD2L1; IFI16; SKA1