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OTX1

Official Full Name

orthodenticle homeobox 1
Overview

homeodomain transcription factor protein; involved in cerebral cortex development
Synonyms

OTX1; orthodenticle homeobox 1; homeobox protein OTX1; FLJ38361; Homeobox protein OTX 1; MGC15736; Orthodenticle 1; Orthodenticle homolog 1; Orthodenticle1; Otx 1; OTX1_HUMAN; OTX1X;

Type

Recombinant Proteins
Cell & Tissue Lysates
Protein Pre-coupled Magnetic Beads

Species

Human
Mouse
Rat

Source

E.coli
HEK293
Mammalian Cell
Wheat Germ

Tag

GST|His
His
His (Fc)
Avi
N/A

Species	Cat.#	Product name	Source (Host)	Tag	Protein Length	Price
Human	OTX1-761H	Recombinant Human OTX1 Protein, GST-His-tagged	E.coli	GST/His		Inquiry
Human	OTX1-30526TH	Recombinant Human OTX1	Wheat Germ	N/A	107 amino acids	Inquiry
Human	OTX1-3512HCL	Recombinant Human OTX1 293 Cell Lysate	HEK293	N/A		Inquiry
Mouse	OTX1-12247M	Recombinant Mouse OTX1 Protein	Mammalian Cell	His		Inquiry
Mouse	OTX1-6441M-B	Recombinant Mouse OTX1 Protein Pre-coupled Magnetic Beads	HEK293			Inquiry
Mouse	OTX1-6441M	Recombinant Mouse OTX1 Protein, His (Fc)-Avi-tagged	HEK293	His (Fc)-Avi		Inquiry
Rat	OTX1-4220R	Recombinant Rat OTX1 Protein	Mammalian Cell	His		Inquiry
Rat	OTX1-3882R-B	Recombinant Rat OTX1 Protein Pre-coupled Magnetic Beads	HEK293			Inquiry
Rat	OTX1-3882R	Recombinant Rat OTX1 Protein, His (Fc)-Avi-tagged	HEK293	His (Fc)-Avi		Inquiry

Involved Pathway
Protein Function
Interacting Protein

OTX1 involved in several pathways and played different roles in them. We selected most pathways OTX1 participated on our site, such as Signaling pathways regulating pluripotency of stem cells, which may be useful for your reference. Also, other proteins which involved in the same pathway with OTX1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name	Pathway Related Protein
Signaling pathways regulating pluripotency of stem cells	PAX6;SMAD2;WNT9B;ONECUT1;HOXB1;PCGF6;INHBA;FGFR3;IL6ST

OTX1 has several biochemical functions, for example, RNA polymerase II core promoter proximal region sequence-specific DNA binding, protein binding, transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding. Some of the functions are cooperated with other proteins, some of the functions could acted by OTX1 itself. We selected most functions OTX1 had, and list some proteins which have the same functions with OTX1. You can find most of the proteins on our site.

Function	Related Protein
RNA polymerase II core promoter proximal region sequence-specific DNA binding	FOXI1;NR2C1;ASCL2;CEBPE;FIGLA;ATF3;ETV6;PDX1;CHD7
protein binding	TAF6L;KRT25;EPHA4;AP3S1;HTT;LSM5;VEZT;PRUNE;RHOA
transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding	EHF;NKX2;TFAP4;EPAS1;TRP63;EGR1;MYB;NFYC;ELF3

OTX1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with OTX1 here. Most of them are supplied by our site. Hope this information will be useful for your research of OTX1.

SPRY2; RGS20; RBPMS; KRTAP4-12; KRTAP10-9