otx1
Share
  • Official Full Name
  • orthodenticle homeobox 1
  • Background
  • homeodomain transcription factor protein; involved in cerebral cortex development
  • Synonyms
  • OTX1; orthodenticle homeobox 1; homeobox protein OTX1; FLJ38361; Homeobox protein OTX 1; MGC15736; Orthodenticle 1; Orthodenticle homolog 1; Orthodenticle1; Otx 1; OTX1_HUMAN; OTX1X
Cat.#:OTX1-30526THTag:
Source (Host):Wheat germSpecies:Human
Product nameRecombinant Human OTX1
+Inquiry
Cat.#:OTX1-761HTag:GST/His
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human OTX1 Protein, GST-His-tagged
+Inquiry
Cat.#:OTX1-12247MTag:His
Source (Host):Mammalian CellsSpecies:Mouse
Product nameRecombinant Mouse OTX1 Protein
+Inquiry
Cat.#:OTX1-4220RTag:His
Source (Host):Mammalian CellsSpecies:Rat
Product nameRecombinant Rat OTX1 Protein
+Inquiry
Cat.#:OTX1-3512HCLTag:
Source (Host):Species:Human
Product nameRecombinant Human OTX1 293 Cell Lysate
+Inquiry

Involved Pathway

OTX1 involved in several pathways and played different roles in them. We selected most pathways OTX1 participated on our site, such as Signaling pathways regulating pluripotency of stem cells, which may be useful for your reference. Also, other proteins which involved in the same pathway with OTX1 were listed below. Creative Biomart supplied nearly all the proteins listed, you can search them on our site.
Pathway Name
Pathway Related Protein
Signaling pathways regulating pluripotency of stem cells
MAP2K1; INHBA; SKIL; HOXB1; PIK3R3; PCGF3; SOX2; PIK3CD; WNT7A; FZD6

Protein Function

OTX1 has several biochemical functions, for example, RNA polymerase II core promoter proximal region sequence-specific DNA binding, protein binding, transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding. Some of the functions are cooperated with other proteins, some of the functions could acted by OTX1 itself. We selected most functions OTX1 had, and list some proteins which have the same functions with OTX1. You can find most of the proteins on our site.
Function
Related Protein
Function RNA polymerase II core promoter proximal region sequence-specific DNA binding
Related Protein SIX4; FOSL2; PITX1; NFAT5; MEF2B; SREBF2; SMAD1; NKX6-2; TBP; NFE2L3
Function protein binding
Related Protein RAP1A; GUCY1B3; GPA33; EIF4G1; POLD3; DNM3; APOH; AGL; RTN3; GZMA
Function transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding
Related Protein POU4F3; HOXD13; ARID3B; ZIC1; FOXD1; MEF2A; KLF13; TFE3; ELK3; MIXL1

Interacting Protein

OTX1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with OTX1 here. Most of them are supplied by our site. Hope this information will be useful for your research of OTX1.
SPRY2; RGS20; RBPMS; KRTAP4-12; KRTAP10-9