p2rx7
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  • Official Full Name
  • P2rx7 purinergic receptor P2X, ligand-gated ion channel, 7
  • Synonyms
  • P2RX7; purinergic receptor P2X, ligand-gated ion channel, 7; P2X purinoceptor 7; ATP receptor; P2Z receptor; P2X7 purinoceptor; purinergic receptor P2X7;
Cat.#:P2RX7-391HTag:His
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human P2RX7 Protein, His-tagged
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Cat.#:P2RX7-1494HTag:GST
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human P2RX7, GST-tagged
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Cat.#:P2RX7-4232RTag:His
Source (Host):Mammalian CellsSpecies:Rat
Product nameRecombinant Rat P2RX7 Protein
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Cat.#:P2RX7-9888ZTag:His
Source (Host):Mammalian CellsSpecies:Zebrafish
Product nameRecombinant Zebrafish P2RX7
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Cat.#:P2RX7-3495HCLTag:
Source (Host):Species:Human
Product nameRecombinant Human P2RX7 293 Cell Lysate
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Involved Pathway

P2RX7 involved in several pathways and played different roles in them. We selected most pathways P2RX7 participated on our site, such as Calcium signaling pathway, Neuroactive ligand-receptor interaction, which may be useful for your reference. Also, other proteins which involved in the same pathway with P2RX7 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
Pathway Name
Pathway Related Protein
Calcium signaling pathway
PLCD1; HRH2; PLCZ1; ATP2A1L; PRKACG; PPIFA; CCKAR; PPP3CC; PTGER1B; EDNRB2
Neuroactive ligand-receptor interaction
GABRA4; CHRNA2; GRIN2BB; GRM6; GHR; GABRG3; CRHR2; NR3C1; HTR1D; EDNRAA

Protein Function

P2RX7 has several biochemical functions, for example, ATP binding, extracellular ATP-gated cation channel activity, lipopolysaccharide binding. Some of the functions are cooperated with other proteins, some of the functions could acted by P2RX7 itself. We selected most functions P2RX7 had, and list some proteins which have the same functions with P2RX7. You can find most of the proteins on our site.
Function
Related Protein
Function ATP binding
Related Protein GARS; AK5; BMP2K; MCM5; CAMK2G1; P2RX6; NOD1; SYN3; CAMKK1; PKM2
Function extracellular ATP-gated cation channel activity
Related Protein P2RX3A; NNR; P2RX3; P2RX5; P2RX2; P2RX4A; P2RX8; P2RX1; P2RX3B; P2RX6
Function lipopolysaccharide binding
Related Protein TLR2; BPIFC; SELP; SCARB1; PSMB4; RNASE7; KIAA0644; HMGB1; TLR4; P2RX7
Function protein binding
Related Protein C6orf108; PHOSPHO2-KLHL23; ERAL1; PPP3R2; MCRS1; PIAS2; BOK; PAK6; MEIS1; BSX
Function protein homodimerization activity
Related Protein FOXP3; SYNDIG1; ZBTB1; PML; NDP; TENM2; NPM1; CPNE1; DROSHA; FAP
Function purinergic nucleotide receptor activity
Related Protein P2RX4B; P2RX3A; P2RX3; P2RX3B; P2RX6; P2RX4A; P2RX1; P2RX8; NNR; P2RX5
Function receptor binding
Related Protein ABCA1; PTK2BB; F2RL1; SMAGP; PICK1; AKAP9; NCK1; PLAT; HLA-G; NXPH3

Interacting Protein

P2RX7 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with P2RX7 here. Most of them are supplied by our site. Hope this information will be useful for your research of P2RX7.
ABL1; NCK1; GRB2; CASK; TM9SF1; EFNB3

P2RX7 Related Articles

Bertelli, R; Di Donato, A; et al. LPS Nephropathy in Mice Is Ameliorated by IL-2 Independently of Regulatory T Cells Activity. PLOS ONE 9:-(2014).
Furlan-Freguia, C; Marchese, P; et al. P2X7 receptor signaling contributes to tissue factor-dependent thrombosis in mice. JOURNAL OF CLINICAL INVESTIGATION 121:2932-2944(2011).