pafah1b2
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  • Official Full Name
  • platelet-activating factor acetylhydrolase 1b, catalytic subunit 2 (30kDa)
  • Background
  • Platelet-activating factor acetylhydrolase (PAFAH) inactivates platelet-activating factor (PAF) into acetate and;LYSO-PAF. This gene encodes the beta subunit of PAFAH, the other subunits are alpha and gamma. Multiple alternatively;spliced transcript variants that encode different protein isoforms have been described for this gene.
  • Synonyms
  • PAFAH1B2; platelet-activating factor acetylhydrolase 1b, catalytic subunit 2 (30kDa); platelet-activating factor acetylhydrolase IB subunit beta; PAF acetylhydrolase 30 kDa subunit; PAF AH 30 kDa subunit; PAF AH beta subunit; PAF AH subunit beta; PAFAH 30 kDa subunit; PAFAH beta subunit; PAFAH subunit beta; PAFAH1B2 protein; PAFAHB; Platelet activating factor acetylhydrolase IB beta subunit; Platelet activating factor acetylhydrolase IB subunit beta; Platelet activating factor acetylhydrolase isoform Ib beta subunit; PAF-AH subunit beta; PAF-AH 30 kDa subunit; platelet-activating factor acetylhydrolase, isoform Ib, subunit 2 (30kDa); platelet-activating factor acetylhydrolase, isoform Ib, beta subunit 30kDa; platelet-activating factor acetylhydrolase, isoform Ib, beta subunit (30kD)
Cat.#:PAFAH1B2-297HTag:His
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human PAFAH1B2 Protein, MYC/DDK-tagged
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Cat.#:PAFAH1B2-596HTag:His
Source (Host):Mammalian CellsSpecies:Human
Product nameRecombinant Human PAFAH1B2
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Cat.#:PAFAH1B2-12308MTag:His
Source (Host):Mammalian CellsSpecies:Mouse
Product nameRecombinant Mouse PAFAH1B2 Protein
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Cat.#:PAFAH1B2-4254RTag:His
Source (Host):Mammalian CellsSpecies:Rat
Product nameRecombinant Rat PAFAH1B2 Protein
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Cat.#:PAFAH1B2-3284RTag:His
Source (Host):Mammalian CellsSpecies:Rhesus Macaque
Product nameRecombinant Rhesus monkey PAFAH1B2 Protein, His-tagged
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Cat.#:PAFAH1B2-2600CTag:His
Source (Host):Mammalian CellsSpecies:Chicken
Product nameRecombinant Chicken PAFAH1B2
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Cat.#:PAFAH1B2-5243ZTag:His
Source (Host):Mammalian CellsSpecies:Zebrafish
Product nameRecombinant Zebrafish PAFAH1B2
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Cat.#:PAFAH1B2-835HTag:His
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human PAFAH1B2, His-tagged
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Cat.#:PAFAH1B2-3468HCLTag:N/A
Source (Host):Species:Human
Product nameRecombinant Human PAFAH1B2 293 Cell Lysate
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Involved Pathway

PAFAH1B2 involved in several pathways and played different roles in them. We selected most pathways PAFAH1B2 participated on our site, such as Ether lipid metabolism, Metabolic pathways, which may be useful for your reference. Also, other proteins which involved in the same pathway with PAFAH1B2 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
Pathway Name
Pathway Related Protein
Ether lipid metabolism
PLA2G16; PPAP2CB; CHPT1; PAFAH2; PPAP2C; PLD3; PPAP2D; PAFAH1B3; PLA2G4A; PLA2G4C
Metabolic pathways
ME1; ALDH3A1; MINPP1; GLCE; GLULB; TREH; HMBSB; PPAP2A; CEPT1; PLCG1

Protein Function

PAFAH1B2 has several biochemical functions, for example, 1-alkyl-2-acetylglycerophosphocholine esterase activity, platelet-activating factor acetyltransferase activity, protein heterodimerization activity. Some of the functions are cooperated with other proteins, some of the functions could acted by PAFAH1B2 itself. We selected most functions PAFAH1B2 had, and list some proteins which have the same functions with PAFAH1B2. You can find most of the proteins on our site.
Function
Related Protein
Function 1-alkyl-2-acetylglycerophosphocholine esterase activity
Related Protein ASPG; PLA2G7; PAFAH2; PAFAH1B3; PAFAH1B2
Function platelet-activating factor acetyltransferase activity
Related Protein PAFAH1B2; PAFAH1B3
Function protein heterodimerization activity
Related Protein TGFB1; HIST1H4K; PRSS28; PKNOX1; ADD1; CXorf15; TOP2A; BOKA; EXT1; NEUROD1
Function protein homodimerization activity
Related Protein HMOX1; DMRTA2; CEBPA; CAMK2A; UGT1A6; STC2; RRAGA; Il6ra; ATPIF1; DEM1

Interacting Protein

PAFAH1B2 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with PAFAH1B2 here. Most of them are supplied by our site. Hope this information will be useful for your research of PAFAH1B2.
Pafah1b1; CRK; EPB41; NME2; MCC; MPG; PRKAB1; TRAF6; PARK2; SNUPN; RPLP0; STAT3; CCT3; ZFP36L1; SLA; PAFAH1B3; TIMM50; REXO1

PAFAH1B2 Related Articles

Salaverria, I; Martin-Guerrero, I; et al. A recurrent 11q aberration pattern characterizes a subset of MYC-negative high-grade B-cell lymphomas resembling Burkitt lymphoma. BLOOD 123:1187-1198(2014).
Peloso, GM; Auer, PL; et al. Association of Low-Frequency and Rare Coding-Sequence Variants with Blood Lipids and Coronary Heart Disease in 56,000 Whites and Blacks. AMERICAN JOURNAL OF HUMAN GENETICS 94:223-232(2014).