Creative BioMart to Present at
                        BIO-Europe Spring Creative BioMart to Present at BIO-Europe Spring|March 18–20, 2024|Booth #34

PAM

  • Official Full Name

    peptidylglycine alpha-amidating monooxygenase

  • Overview

    This gene encodes a multifunctional protein. It has two enzymatically active domains with catalytic activities - peptidylglycine alpha-hydroxylating monooxygenase (PHM) and peptidyl-alpha-hydroxyglycine alpha-amidating lyase (PAL). These catalytic domains work sequentially to catalyze neuroendocrine peptides to active alpha-amidated products. Multiple alternatively spliced transcript variants encoding different isoforms have been described for this gene but some of their full length sequences are not yet known.
  • Synonyms

    PAM; peptidylglycine alpha-amidating monooxygenase; peptidyl-glycine alpha-amidating monooxygenase; PAL; peptidyl alpha hydroxyglycine alpha amidating lyase; peptidylglycine alpha hydroxylating monooxygenase; PHM; AMD_HUMAN; Pancreatic peptidylglycine alpha amidating monooxygenase; Peptidyl alpha amidating enzyme; Peptidyl-alpha-hydroxyglycine alpha-amidating lyase; Peptidylamidoglycolate lyase; Peptidylglycine 2 hydroxylase; Peptidylglycine alpha amidating monooxygenase; OTTHUMP00000158920; OTTHUMP00000158921; OTTHUMP00000158922; OTTHUMP00000158923; OTTHUMP00000222752; OTTHUMP00000227957; peptidylglycine 2-hydroxylase; peptidyl alpha-amidating enzyme; pep;

  • Recombinant Proteins
  • Cell & Tissue Lysates
  • Protein Pre-coupled Magnetic Beads
  • Human
  • Mouse
  • Rat
  • E.coli
  • HEK293
  • HEK293F
  • HEK293T
  • In Vitro Cell Free System
  • Mammalian Cell
  • Mammalian cells
  • Wheat Germ
  • Fc
  • His
  • His (Fc)
  • Avi
  • Myc
  • DDK
  • N/A
  • N
Species Cat.# Product name Source (Host) Tag Protein Length Price
Human PAM-495H Active Recombinant Human Peptidylglycine Alpha-Amidating Monooxygenase, His-tagged Mammalian cells His
Human PAM-30777TH Recombinant Human PAM Wheat Germ N/A 866 amino acids
Human PAM-30780TH Recombinant Human PAM Wheat Germ N/A 108 amino acids
Human PAM-559H Recombinant Human PAM Protein, Fc-tagged HEK293 Fc
Human PAM-1519H Recombinant Human PAM, His-tagged E.coli His 24-386aa
Human PAM-560H Recombinant Human PAM Protein, His-tagged HEK293 His
Human PAM-3448HCL Recombinant Human PAM 293 Cell Lysate HEK293 N/A
Human PAM-1281H Recombinant Human PAM Protein, Myc/DDK-tagged, C13 and N15-labeled HEK293T Myc/DDK
Human PAM-2542H Recombinant Human PAM Protein, His-tagged E.coli N-His Phe21-Cys288
Human PAM-3788H-B Recombinant Human PAM Protein Pre-coupled Magnetic Beads HEK293
Human PAM-357HF Recombinant Full Length Human PAM Protein In Vitro Cell Free System 866 amino acids
Human PAM-3788H Recombinant Human PAM Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Mouse Pam-4666M Recombinant Mouse Pam Protein, Myc/DDK-tagged HEK293T Myc/DDK
Rat PAM-4264R Recombinant Rat PAM Protein Mammalian Cell His
Rat PAM-3926R-B Recombinant Rat PAM Protein Pre-coupled Magnetic Beads HEK293
Rat Pam-1169R Recombinant Rat Pam Protein, His-tagged HEK293F N-His Phe36-Val820
Rat PAM-3926R Recombinant Rat PAM Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Rat Pam-1170R Recombinant Rat Pam Protein, His-tagged HEK293F N-His Phe36-Val820
  • Involved Pathway
  • Protein Function
  • Interacting Protein
  • PAM Related Articles

PAM involved in several pathways and played different roles in them. We selected most pathways PAM participated on our site, such as , which may be useful for your reference. Also, other proteins which involved in the same pathway with PAM were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name Pathway Related Protein

PAM has several biochemical functions, for example, L-ascorbic acid binding, copper ion binding, peptidylamidoglycolate lyase activity. Some of the functions are cooperated with other proteins, some of the functions could acted by PAM itself. We selected most functions PAM had, and list some proteins which have the same functions with PAM. You can find most of the proteins on our site.

Function Related Protein
L-ascorbic acid bindingDBH;P3H2;EGLN3;LEPRE1;OGFOD2;PLOD1;TMLHE;P4HA2;P4HTM
copper ion bindingHIST2H3A;PAM;MT3;LOXL5A;COX17;S100A12;P2RX4;SNAI3;TYRP1B
peptidylamidoglycolate lyase activity
peptidylglycine monooxygenase activity
protein bindingC21orf56;ZKSCAN17;TBXA2R;BIRC3;LILRA4;RFWD2;MAGEH1;TRPM6;ACTG1
zinc ion bindingPHF23;MAN2A1;S100A9;ADAM25;MSL2B;SUPT4H1;RNF111;ADAM9;TRIM24

PAM has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with PAM here. Most of them are supplied by our site. Hope this information will be useful for your research of PAM.

DEDD; PRKAR1A

Mallo, N; Lamas, J; et al. Presence of a plant-like proton-translocating pyrophosphatase in a scuticociliate parasite and its role as a possible drug target. PARASITOLOGY 142:449-462(2015).
Pone, EJ; Lou, Z; et al. B cell TLR1/2, TLR4, TLR7 and TLR9 interact in induction of class switch DNA recombination: Modulation by BCR and CD40, and relevance to T-independent antibody responses. AUTOIMMUNITY 48:1-12(2015).
  • Q&As
  • Reviews

Q&As (0)

Ask a question

Customer Reviews (3)

Write a review
Reviews
10/17/2022

    When employed in Western Blotting experiments, the PAM protein consistently generates sharp and well-defined protein bands, enabling precise visualization and analysis of protein expression.

    01/01/2022

      I am extremely pleased with the quality of the PAM protein as it perfectly fulfills my experimental requirements.

      11/16/2020

        This protein exhibits exceptional purity and reliability, ensuring accurate and reproducible results in my assays.

        Ask a Question for All PAM Products

        Required fields are marked with *

        My Review for All PAM Products

        Required fields are marked with *

        logo

        FOLLOW US

        Terms and Conditions        Privacy Policy

        Copyright © 2024 Creative BioMart. All Rights Reserved.

        Contact Us

        • /

        Stay Updated on the Latest Bioscience Trends