Recombinant Full Length Human PAM Protein
| Cat.No. : | PAM-357HF |
| Product Overview : | Recombinant full length Human PAM isoform 2 , with N terminal proprietary tag; Predicted MW 121.26kDa. |
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| Species : | Human |
| Source : | In Vitro Cell Free System |
| Protein Length : | 866 amino acids |
| Description : | This gene encodes a multifunctional protein. It has two enzymatically active domains with catalytic activities - peptidylglycine alpha-hydroxylating monooxygenase (PHM) and peptidyl-alpha-hydroxyglycine alpha-amidating lyase (PAL). These catalytic domains work sequentially to catalyze neuroendocrine peptides to active alpha-amidated products. Multiple alternatively spliced transcript variants encoding different isoforms have been described for this gene but some of their full length sequences are not yet known. |
| Form : | Liquid |
| Molecular Mass : | 121.260kDa inclusive of tags |
| AA Sequence : | MAGRVPSLLVLLVFPSSCLAFRSPLSVFKRFKETTRPFSN ECLGTTRPVVPIDSSDFALDIRMPGVTPKQSDTYFCMSMR IPVDEEAFVIDFKPRASMDTVHHMLLFGCNMPSSTGSYWF CDEGTCTDKANILYAWARNAPPTRLPKGVGFRVGGETGSK YFVLQVHYGDISAFRDNNKDCSGVSLHLTRLPQPLIAGMY LMMSVDTVIPAGEKVVNSDISCHYKNYPMHVFAYRVHTHH LGKVVSGYRVRNGQWTLIGRQSPQLPQAFYPVGHPVDVSF GDLLAARCVFTGEGRTEATHIGGTSSDEMCNLYIMYYMEA KHAVSFMTCTQNVAPDMFRTIPPEANIPIPVKSDMVMMHE HHKETEYKDKIPLLQQPKREEEEVLDQDFHMEEALDWPGV YLLPGQVSGVALDPKNNLVIFHRGDHVWDGNSFDSKFVYQ QIGLGPIEEDTILVIDPNNAAVLQSSGKNLFYLPHGLSID KDGNYWVTDVALHQVFKLDPNNKEGPVLILGRSMQPGSDQ NHFCQPTDVAVDPGTGAIYVSDGYCNSRIVQFSPSGKFIT QWGEESSGSSPLPGQFTVPHSLALVPLLGQLCVADRENGR IQCFKTDTKEFVREIKHSSFGRNVFAISYIPGLLFAVNGK PHFGDQEPVQGFVMNFSNGEIIDIFKPVRKHFDMPHDIVA SEDGTVYIGDAHTNTVWKFTLTEKLEHRSVKKAGIEVQEI KEAEAVVETKMENKPTSSELQKMQEKQKLIKEPGSGVPVV LITTLLVIPVVVLLAIAIFIRWKKSRAFGDSEHKLETSSG RVLGRFRGKGSGGLNLGNFFASRKGYSRKGFDRLSTEGSD QEKEDDGSESEEEYSAPLPALAPSSS |
| Purity : | Proprietary Purification |
| Storage : | Shipped on dry ice. Upon delivery aliquot and store at -80 centigrade. Avoid freeze / thaw cycles. |
| Storage Buffer : | pH: 8.00. Constituents:0.79% Tris HCl, 0.31% Glutathione. |
| Gene Name | PAM peptidylglycine alpha-amidating monooxygenase [ Homo sapiens ] |
| Official Symbol | PAM |
| Synonyms | PAM; peptidylglycine alpha-amidating monooxygenase; peptidyl-glycine alpha-amidating monooxygenase; PAL; peptidyl alpha hydroxyglycine alpha amidating lyase; peptidylglycine alpha hydroxylating monooxygenase; PHM |
| Gene ID | 5066 |
| mRNA Refseq | NM_000919 |
| Protein Refseq | NP_000910 |
| MIM | 170270 |
| UniProt ID | P19021 |
Not For Human Consumption!
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