pax7
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  • Official Full Name
  • paired box 7
  • Background
  • This gene is a member of the paired box (PAX) family of transcription factors. Members of this gene family typically contain a paired box domain, an octapeptide, and a paired-type homeodomain. These genes play critical roles during fetal development and cancer growth. The specific function of the paired box 7 gene is unknown but speculated to involve tumor suppression since fusion of this gene with a forkhead domain family member has been associated with alveolar rhabdomyosarcoma. Three transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2008]
  • Synonyms
  • PAX7; paired box 7; HUP1; RMS2; PAX7B; paired box protein Pax-7; paired domain gene 7; paired box homeotic gene 7; PAX7 transcriptional factor;
Cat.#:PAX7-132HTag:T7|His
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human PAX7 protein, T7/His-tagged
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Cat.#:PAX7-29057THTag:N/A
Source (Host):Wheat germSpecies:Human
Product nameRecombinant Human PAX7
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Cat.#:PAX7-6622CTag:His
Source (Host):Mammalian CellsSpecies:Chicken
Product nameRecombinant Chicken PAX7
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Cat.#:PAX7-3413HCLTag:N/A
Source (Host):Species:Human
Product nameRecombinant Human PAX7 293 Cell Lysate
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Cat.#:PAX7-3414HCLTag:N/A
Source (Host):Species:Human
Product nameRecombinant Human PAX7 293 Cell Lysate
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Involved Pathway

PAX7 involved in several pathways and played different roles in them. We selected most pathways PAX7 participated on our site, such as Transcriptional misregulation in cancer, which may be useful for your reference. Also, other proteins which involved in the same pathway with PAX7 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
Pathway Name
Pathway Related Protein
Transcriptional misregulation in cancer
MLF1; EWSR1; HIST1H3I; TGFBR2; TAF15; ETV7; IL3; HIST2H3A; PRCC; KLF3

Protein Function

PAX7 has several biochemical functions, for example, sequence-specific DNA binding, transcription factor activity, RNA polymerase II core promoter sequence-specific, transcription factor activity, sequence-specific DNA binding. Some of the functions are cooperated with other proteins, some of the functions could acted by PAX7 itself. We selected most functions PAX7 had, and list some proteins which have the same functions with PAX7. You can find most of the proteins on our site.
Function
Related Protein
Function sequence-specific DNA binding
Related Protein SP1; RORAA; NR6A1; ZNF274; FOXR1; GRHL2B; ELF2; LHX8A; SIX1B; PRRX1B
Function transcription factor activity, RNA polymerase II core promoter sequence-specific
Related Protein TFAP2B; NKX3; PAX7; HEYL; HEY2; HEY1; SMAD3; MAX; MEF2C
Function transcription factor activity, sequence-specific DNA binding
Related Protein ZBTB11; PBX1B; ZNF192; ZNF792; GM239; GPBP1; ZNF232; MESPBA; E4F1; TRIM22

Interacting Protein

PAX7 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with PAX7 here. Most of them are supplied by our site. Hope this information will be useful for your research of PAX7.
Dlg4; FYN; SRC; AKR1B1; NCK1; CRK

PAX7 Related Articles

Gautam, SS; Imamura, T; et al. Implantation of Autologous Adipose-Derived Cells Reconstructs Functional Urethral Sphincters in Rabbit Cryoinjured Urethra. TISSUE ENGINEERING PART A 20:1971-1979(2014).
Bandin, S; Morona, R; et al. Immunohistochemical analysis of Pax6 and Pax7 expression in the CNS of adult Xenopus laevis. JOURNAL OF CHEMICAL NEUROANATOMY 57-58:24-41(2014).