PDE7A

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PDE7A

Official Full Name PDE7A phosphodiesterase 7A
Background Cyclic nucleotide phosphodiesterases (PDEs) catalyse the hydrolytic inactivation of the common intracellular second messengers cyclic adenosine and guanosine 3, 5monophosphate (cAMP and cGMP). Thus, these enzymes play a critical role in the regulation of a wide range of physiological processes modulated by cyclic nucleotide signalling. The PDE5 enzyme belongs to a family of cGMPdependent PDEs that provide the major means of inactivating the key intracellular second messenger, cGMP
Synonyms PDE7A; phosphodiesterase 7A; high affinity cAMP-specific 3,5-cyclic phosphodiesterase 7A; HCP1; TM22; phosphodiesterase isozyme 7; PDE7
    • Species :
    • Human
    • Mouse
    • Rat
    • Rhesus Macaque
    • Zebrafish
    • Source :
    • E.coli
    • HEK293
    • Insect Cell
    • Mammalian Cell
    • Sf9 Insect Cell
    • Tag :
    • GST
    • His
    • N/A
    Species Cat.# Product name Source (Host) Tag Protein Length Price
    Human PDE7A-1531H Recombinant Human PDE7A (Active), GST-tagged Sf9 Insect Cell GST
    Human PDE7A-1606H Recombinant Human PDE7A, GST-tagged E.coli GST
    Human PDE7A-332H Recombinant Human PDE7A Mammalian Cell His
    Human PDE7A-3341HCL Recombinant Human PDE7A 293 Cell Lysate HEK293 N/A
    Human PDE7A-3342HCL Recombinant Human PDE7A 293 Cell Lysate HEK293 N/A
    Human PDE7A-356H Recombinant Human PDE7A protein E.coli N/A
    Human PDE7A-481H Recombinant Human Phosphodiesterase 7A, GST-tagged, Active Sf9 Insect Cell GST
    Mouse PDE7A-12562M Recombinant Mouse PDE7A Protein Mammalian Cell His
    Rat Pde7a-1543R Recombinant Rat Pde7a protein, GST-tagged Insect Cell GST
    Rhesus Macaque PDE7A-3351R Recombinant Rhesus monkey PDE7A Protein, His-tagged Mammalian Cell His
    Zebrafish PDE7A-7636Z Recombinant Zebrafish PDE7A Mammalian Cell His
    Kit-1847 PDE7A Assay Kit N/A

    PDE7A involved in several pathways and played different roles in them. We selected most pathways PDE7A participated on our site, such as Purine metabolism, Morphine addiction, which may be useful for your reference. Also, other proteins which involved in the same pathway with PDE7A were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein
    Purine metabolism POLR1C; AK1; POLR2F; PAPSS2A; GDA; NME4; PDE6G; Adcy4; POLR3GLB; NUDT16
    Morphine addiction GABRR1; GNG8; GABRQ; GNB2; GNGT2; ARRB1; GNG13; PDE7A; OPRM1; PRKCG

    PDE7A has several biochemical functions, for example, 3,5-cyclic-AMP phosphodiesterase activity, metal ion binding. Some of the functions are cooperated with other proteins, some of the functions could acted by PDE7A itself. We selected most functions PDE7A had, and list some proteins which have the same functions with PDE7A. You can find most of the proteins on our site.

    Function Related Protein
    3,5-cyclic-AMP phosphodiesterase activity PDE8A; PDE3A; TDP2B; PDE4C; USB1; PDE4B; PDE7B; PDE4A; PDE1B; PDE8B
    metal ion binding ITPK1A; PPP2CA; NUDT12; ZDHHC16A; SCD5; NR2F6B; RNF220A; ZFP28; TRAF4A; Fcer2a

    PDE7A has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with PDE7A here. Most of them are supplied by our site. Hope this information will be useful for your research of PDE7A.

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