pde7a
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  • Official Full Name
  • PDE7A phosphodiesterase 7A
  • Background
  • Cyclic nucleotide phosphodiesterases (PDEs) catalyse the hydrolytic inactivation of the common intracellular second messengers cyclic adenosine and guanosine 3, 5monophosphate (cAMP and cGMP). Thus, these enzymes play a critical role in the regulation of a wide range of physiological processes modulated by cyclic nucleotide signalling. The PDE5 enzyme belongs to a family of cGMPdependent PDEs that provide the major means of inactivating the key intracellular second messenger, cGMP
  • Synonyms
  • PDE7A; phosphodiesterase 7A; high affinity cAMP-specific 3,5-cyclic phosphodiesterase 7A; HCP1; TM22; phosphodiesterase isozyme 7; PDE7
Cat.#:PDE7A-1606HTag:GST
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human PDE7A, GST-tagged
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Cat.#:PDE7A-332HTag:His
Source (Host):Mammalian CellsSpecies:Human
Product nameRecombinant Human PDE7A
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Cat.#:PDE7A-356HTag:
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human PDE7A protein
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Cat.#:PDE7A-481HTag:GST
Source (Host):Sf 9 Insect cellsSpecies:Human
Product nameRecombinant Human Phosphodiesterase 7A, GST-tagged, Active
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Cat.#:PDE7A-12562MTag:His
Source (Host):Mammalian CellsSpecies:Mouse
Product nameRecombinant Mouse PDE7A Protein
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Cat.#:Pde7a-1543RTag:GST
Source (Host):Insect cellsSpecies:Rat
Product nameRecombinant Rat Pde7a protein, GST-tagged
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Cat.#:PDE7A-3351RTag:His
Source (Host):Mammalian CellsSpecies:Rhesus Macaque
Product nameRecombinant Rhesus monkey PDE7A Protein, His-tagged
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Cat.#:PDE7A-7636ZTag:His
Source (Host):Mammalian CellsSpecies:Zebrafish
Product nameRecombinant Zebrafish PDE7A
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Cat.#:PDE7A-1531HTag:GST
Source (Host):Sf 9 Insect cellsSpecies:Human
Product nameRecombinant Human PDE7A (Active), GST-tagged
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Cat.#:PDE7A-3341HCLTag:
Source (Host):Species:Human
Product nameRecombinant Human PDE7A 293 Cell Lysate
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Cat.#:PDE7A-3342HCLTag:
Source (Host):Species:Human
Product nameRecombinant Human PDE7A 293 Cell Lysate
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Cat.#:Kit-1847Tag:
Source (Host):Species:
Product namePDE7A Assay Kit
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Involved Pathway

PDE7A involved in several pathways and played different roles in them. We selected most pathways PDE7A participated on our site, such as Purine metabolism, Morphine addiction, which may be useful for your reference. Also, other proteins which involved in the same pathway with PDE7A were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
Pathway Name
Pathway Related Protein
Purine metabolism
NT5C1B-RDH14; POLR3GL; NUDT9; ALLC; TM9SF1; RRM2B; NPR2; ENPP1; ADSSL; GUK1A
Morphine addiction
PDE8B; GABRG3; GNG3; GNGT2; GNG13; GABBR1; GNB1; GABRR2; DRD1A; GNG12

Protein Function

PDE7A has several biochemical functions, for example, 3,5-cyclic-AMP phosphodiesterase activity, metal ion binding. Some of the functions are cooperated with other proteins, some of the functions could acted by PDE7A itself. We selected most functions PDE7A had, and list some proteins which have the same functions with PDE7A. You can find most of the proteins on our site.
Function
Related Protein
Function 3,5-cyclic-AMP phosphodiesterase activity
Related Protein PDE8B; PDE1B; PDE4A; PDE7A; PDE4D; TDP2B; PDE4C; PDE8A; PDE4B; PDE7B
Function metal ion binding
Related Protein NEK8; ZBBX; ISL2B; FBP2; RNF145B; SEMG1; ZNF608; DGKQ; NOS2A; CYP2K17

Interacting Protein

PDE7A has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with PDE7A here. Most of them are supplied by our site. Hope this information will be useful for your research of PDE7A.
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