|Official Full Name||phosphodiesterase 7B|
|Background||The 3,5-cyclic nucleotides cAMP and cGMP function as second messengers in a wide variety of signal transduction pathways. 3,5-cyclic nucleotide phosphodiesterases (PDEs) catalyze the hydrolysis of cAMP and cGMP to the corresponding 5-monophosphates and provide a mechanism to downregulate cAMP and cGMP signaling. This gene encodes a cAMP-specific phosphodiesterase, a member of the cyclic nucleotide phosphodiesterase family.|
|Synonyms||PDE7B; phosphodiesterase 7B; cAMP-specific 3,5-cyclic phosphodiesterase 7B; rolipram-insensitive phosphodiesterase type 7; high-affinity cAMP-specific 3,5-cyclic phosphodiesterase; bA472E5.1; MGC88256|
|Species||Cat.#||Product name||Source (Host)||Tag||Protein Length||Price|
PDE7B involved in several pathways and played different roles in them. We selected most pathways PDE7B participated on our site, such as Purine metabolism, Morphine addiction, which may be useful for your reference. Also, other proteins which involved in the same pathway with PDE7B were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
|Pathway Name||Pathway Related Protein|
|Purine metabolism||ADSSL; PKM; GDA; PGM2; AK3; POLR2D; FHIT; POLR3F; PRPS1; POLR1B|
|Morphine addiction||GABRA5; PDE8B; GABRA1; PDE4B; PRKCG; PDE3A; GNAI2; PDE3B; GNAI1; GNB1|
PDE7B has several biochemical functions, for example, 3,5-cyclic-AMP phosphodiesterase activity, metal ion binding. Some of the functions are cooperated with other proteins, some of the functions could acted by PDE7B itself. We selected most functions PDE7B had, and list some proteins which have the same functions with PDE7B. You can find most of the proteins on our site.
|3,5-cyclic-AMP phosphodiesterase activity||PDE4B; PDE7A; PDE4A; PDE4D; PDE7B; PDE8A; PDE8B; PDE4C; USB1; TDP2B|
|metal ion binding||ACVRL1; ZMYND12; RNF17; GBGT1; ARMC1; ZBED5; USP19; CYP4V7; SP7; SNAI1A|
PDE7B has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with PDE7B here. Most of them are supplied by our site. Hope this information will be useful for your research of PDE7B.