pde7b
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  • Official Full Name
  • phosphodiesterase 7B
  • Background
  • The 3,5-cyclic nucleotides cAMP and cGMP function as second messengers in a wide variety of signal transduction pathways. 3,5-cyclic nucleotide phosphodiesterases (PDEs) catalyze the hydrolysis of cAMP and cGMP to the corresponding 5-monophosphates and provide a mechanism to downregulate cAMP and cGMP signaling. This gene encodes a cAMP-specific phosphodiesterase, a member of the cyclic nucleotide phosphodiesterase family.
  • Synonyms
  • PDE7B; phosphodiesterase 7B; cAMP-specific 3,5-cyclic phosphodiesterase 7B; rolipram-insensitive phosphodiesterase type 7; high-affinity cAMP-specific 3,5-cyclic phosphodiesterase; bA472E5.1; MGC88256
Cat.#:PDE7B-1607HTag:His
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human PDE7B, His-tagged
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Cat.#:PDE7B-30224THTag:
Source (Host):Species:Human
Product nameRecombinant Human PDE7B
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Cat.#:PDE7B-30823THTag:
Source (Host):Baculovirus-Insect CellsSpecies:Human
Product nameRecombinant Human PDE7B
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Cat.#:PDE7B-446HTag:GST
Source (Host):Sf 9 Insect cellsSpecies:Human
Product nameRecombinant Human Phosphodiesterase 7B, GST-tagged
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Cat.#:PDE7B-1532HTag:GST
Source (Host):Sf 9 Insect cellsSpecies:Human
Product nameRecombinant Human PDE7B (Active), GST-tagged
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Cat.#:PDE7B-3340HCLTag:
Source (Host):Species:Human
Product nameRecombinant Human PDE7B 293 Cell Lysate
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Cat.#:Kit-1848Tag:
Source (Host):Species:
Product namePDE7B Assay Kit
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Involved Pathway

PDE7B involved in several pathways and played different roles in them. We selected most pathways PDE7B participated on our site, such as Purine metabolism, Morphine addiction, which may be useful for your reference. Also, other proteins which involved in the same pathway with PDE7B were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
Pathway Name
Pathway Related Protein
Purine metabolism
XDH; TM9SF1; PDE10A; POLR1C; GUK1; URAH; TWISTNB; POLR3B; NME2B.1; POLR1D
Morphine addiction
GNAO1; GABBR1; PDE10A; GABRA4; ADRBK2; PDE4A; PDE8A; PDE3A; GNG5; PDE4D

Protein Function

PDE7B has several biochemical functions, for example, 3,5-cyclic-AMP phosphodiesterase activity, metal ion binding. Some of the functions are cooperated with other proteins, some of the functions could acted by PDE7B itself. We selected most functions PDE7B had, and list some proteins which have the same functions with PDE7B. You can find most of the proteins on our site.
Function
Related Protein
Function 3,5-cyclic-AMP phosphodiesterase activity
Related Protein PDE3A; PDE8B; USB1; PDE8A; PDE7B; PDE4A; PDE4B; PDE4D; PDE7A; TDP2B
Function metal ion binding
Related Protein MGRN1A; ZBTB41; ZNF766; USP19; SMYD5; RC3H2; ZNF740; PARP12B; IRF2BPL; GDPD1

Interacting Protein

PDE7B has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with PDE7B here. Most of them are supplied by our site. Hope this information will be useful for your research of PDE7B.
SRPK2