PDE7B

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PDE7B

Official Full Name phosphodiesterase 7B
Background The 3,5-cyclic nucleotides cAMP and cGMP function as second messengers in a wide variety of signal transduction pathways. 3,5-cyclic nucleotide phosphodiesterases (PDEs) catalyze the hydrolysis of cAMP and cGMP to the corresponding 5-monophosphates and provide a mechanism to downregulate cAMP and cGMP signaling. This gene encodes a cAMP-specific phosphodiesterase, a member of the cyclic nucleotide phosphodiesterase family.
Synonyms PDE7B; phosphodiesterase 7B; cAMP-specific 3,5-cyclic phosphodiesterase 7B; rolipram-insensitive phosphodiesterase type 7; high-affinity cAMP-specific 3,5-cyclic phosphodiesterase; bA472E5.1; MGC88256
    • Species :
    • Human
    • Mouse
    • Source :
    • E.coli
    • HEK293
    • HEK293T
    • Insect Cell
    • Sf9 Insect Cell
    • Tag :
    • GST
    • His
    • Myc/DDK
    • N/A
    Species Cat.# Product name Source (Host) Tag Protein Length Price
    Mouse Pde7b-4752M Recombinant Mouse Pde7b Protein, Myc/DDK-tagged HEK293T Myc/DDK
    Human PDE7B-1532H Recombinant Human PDE7B (Active), GST-tagged Sf9 Insect Cell GST
    Human PDE7B-1607H Recombinant Human PDE7B, His-tagged E.coli His
    Human PDE7B-30224TH Recombinant Human PDE7B N/A
    Human PDE7B-30823TH Recombinant Human PDE7B Insect Cell N/A
    Human PDE7B-3340HCL Recombinant Human PDE7B 293 Cell Lysate HEK293 N/A
    Human PDE7B-446H Recombinant Human Phosphodiesterase 7B, GST-tagged Sf9 Insect Cell GST
    Kit-1848 PDE7B Assay Kit N/A

    PDE7B involved in several pathways and played different roles in them. We selected most pathways PDE7B participated on our site, such as Purine metabolism, Morphine addiction, which may be useful for your reference. Also, other proteins which involved in the same pathway with PDE7B were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein
    Purine metabolism ADSSL; PKM; GDA; PGM2; AK3; POLR2D; FHIT; POLR3F; PRPS1; POLR1B
    Morphine addiction GABRA5; PDE8B; GABRA1; PDE4B; PRKCG; PDE3A; GNAI2; PDE3B; GNAI1; GNB1

    PDE7B has several biochemical functions, for example, 3,5-cyclic-AMP phosphodiesterase activity, metal ion binding. Some of the functions are cooperated with other proteins, some of the functions could acted by PDE7B itself. We selected most functions PDE7B had, and list some proteins which have the same functions with PDE7B. You can find most of the proteins on our site.

    Function Related Protein
    3,5-cyclic-AMP phosphodiesterase activity PDE4B; PDE7A; PDE4A; PDE4D; PDE7B; PDE8A; PDE8B; PDE4C; USB1; TDP2B
    metal ion binding ACVRL1; ZMYND12; RNF17; GBGT1; ARMC1; ZBED5; USP19; CYP4V7; SP7; SNAI1A

    PDE7B has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with PDE7B here. Most of them are supplied by our site. Hope this information will be useful for your research of PDE7B.

    SRPK2

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