pdgfrl
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  • Official Full Name
  • platelet-derived growth factor receptor-like
  • Background
  • This gene encodes a protein with significant sequence similarity to the ligand binding domain of platelet-derived growth factor receptor beta. Mutations in this gene, or deletion of a chromosomal segment containing this gene, are associated with sporadic hepatocellular carcinomas, colorectal cancers, and non-small cell lung cancers. This suggests this gene product may function as a tumor suppressor.
  • Synonyms
  • PDGFRL; platelet-derived growth factor receptor-like; platelet-derived growth factor receptor-like protein; PRLTS; PDGFR-like protein; PDGF receptor beta-like tumor suppressor; platelet-derived growth factor-beta-like tumor suppressor; PDGRL
Cat.#:PDGFRL-704HTag:His
Source (Host):Mammalian CellsSpecies:Human
Product nameRecombinant Human PDGFRL
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Cat.#:PDGFRL-8159HTag:His/GST
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human PDGFRL protein, His & GST-tagged
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Cat.#:Pdgfrl-8160MTag:His/T7
Source (Host):E. coliSpecies:Mouse
Product nameRecombinant Mouse Pdgfrl protein, His & T7-tagged
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Cat.#:PDGFRL-4341RTag:His
Source (Host):Mammalian CellsSpecies:Rat
Product nameRecombinant Rat PDGFRL Protein
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Cat.#:PDGFRL-777CTag:His
Source (Host):Mammalian CellsSpecies:Cynomolgus Monkey
Product nameRecombinant Cynomolgus PDGFRL Protein, His-tagged
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Cat.#:PDGFRL-10643ZTag:His
Source (Host):Mammalian CellsSpecies:Zebrafish
Product nameRecombinant Zebrafish PDGFRL
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Cat.#:PDGFRL-3334HCLTag:
Source (Host):Species:Human
Product nameRecombinant Human PDGFRL 293 Cell Lysate
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Protein Function

PDGFRL has several biochemical functions, for example, platelet activating factor receptor activity, platelet-derived growth factor beta-receptor activity. Some of the functions are cooperated with other proteins, some of the functions could acted by PDGFRL itself. We selected most functions PDGFRL had, and list some proteins which have the same functions with PDGFRL. You can find most of the proteins on our site.
Function
Related Protein
Function platelet activating factor receptor activity
Related Protein PDGFRL; PTAFR; PDGFRB
Function platelet-derived growth factor beta-receptor activity
Related Protein PDGFRL; PDGFRB

Interacting Protein

PDGFRL has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with PDGFRL here. Most of them are supplied by our site. Hope this information will be useful for your research of PDGFRL.
TMEM129; FBP2; CTSV; HRAS; TGFB1; MBP; PFKM; XPA; RANGAP1; MAPK12; PPP2CB; FANCC; MAP2K1; ASPH; BAAT; SPARCL1; SMAD1; MAPKAPK3; SFRP4; PPP3R2

PDGFRL Related Articles

Persson, C; Sjoblom, T; et al. Preferential oxidation of the second phosphatase domain of receptor-like PTP-alpha revealed by an antibody against oxidized protein tyrosine phosphatases. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 101:1886-1891(2004).
Kim, SB; Yang, WS; et al. Lipocortin-1 inhibits proliferation of cultured human mesangial cells. NEPHRON 74:39-44(1996).