pdlim5
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  • Official Full Name
  • PDZ and LIM domain 5
  • Background
  • The protein encoded by this gene is a LIM domain protein. LIM domains are cysteine-rich double zinc fingers composed of 50 to 60 amino acids that are involved in protein-protein interactions. LIM domain-containing proteins are scaffolds for the formation of multiprotein complexes. The proteins are involved in cytoskeleton organization, cell lineage specification, organ development, and oncogenesis. The encoded protein is also a member of the Enigma class of proteins, a family of proteins that possess a 100-amino acid PDZ domain in the N terminus and 1 to 3 LIM domains in the C terminus. Multiple transcript variants encoding different isoforms have been found for this gene, although not all of them have been fully characterized.
  • Synonyms
  • PDLIM5; PDZ and LIM domain 5; PDZ and LIM domain protein 5; Enh; LIM; ENH1; Enigma homolog; Enigma like LIM domain protein; Enigma like PDZ and LIM domains protein; L 9; L9; OTTHUMP00000161598; OTTHUMP00000219307; OTTHUMP00000219309; OTTHUMP00000219310; OTTHUMP00000227958; enigma-like LIM domain protein; enigma-like PDZ and LIM domains protein
Cat.#:PDLIM5-1624HTag:GST
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human PDLIM5, GST-tagged
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Cat.#:PDLIM5-4354RTag:His
Source (Host):Mammalian CellsSpecies:Rat
Product nameRecombinant Rat PDLIM5 Protein
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Cat.#:PDLIM5-2821CTag:His
Source (Host):Mammalian CellsSpecies:Chicken
Product nameRecombinant Chicken PDLIM5
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Cat.#:PDLIM5-3325HCLTag:N/A
Source (Host):Species:Human
Product nameRecombinant Human PDLIM5 293 Cell Lysate
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Protein Function

PDLIM5 has several biochemical functions, for example, actin binding, actinin binding, protein N-terminus binding. Some of the functions are cooperated with other proteins, some of the functions could acted by PDLIM5 itself. We selected most functions PDLIM5 had, and list some proteins which have the same functions with PDLIM5. You can find most of the proteins on our site.
Function
Related Protein
Function actin binding
Related Protein FMN1; PHACTR3; ACTN4; CLMN; GC; FSCN2; WASF1; HPCA; FLII; ALKBH4
Function actinin binding
Related Protein RELA; NFKB1; PKD2; TTN; PDLIM5; MICALL2; CSRP3; PROM1
Function protein N-terminus binding
Related Protein KCNB1; NIPBL; ID1; ZWINT; ALOX5AP; TBL1XR1; TDRD7; RASSF1; MORF4L1; RBPJ
Function protein binding
Related Protein RALY; POLRMT; CCNB2; FKBP1B; VPS33A; ZFYVE16; TRPC4AP; UHRF2; GLMN; MZT1
Function protein kinase C binding
Related Protein PKN1; TRPV4; PAWR; IRS1; FLNA; TIRAP; AVPR1B; C1QBP; TDG; TOP2B
Function zinc ion binding
Related Protein PCGF2; PHF2; RCHY1; NR1H2; RNF10; LMX1A; ZACN; ZNF146; QPCT; TRHDE

Interacting Protein

PDLIM5 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with PDLIM5 here. Most of them are supplied by our site. Hope this information will be useful for your research of PDLIM5.
COIL; KRTAP10-7; ZYX; KRT40; CCDC136; GFI1B; q7cii8_yerpe; TRIM39; q9wmx2-pro_0000037548; npm_alk