PLA2G2A Protein, phospholipase A2, group IIA (platelets, synovial fluid)


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Official Full Name phospholipase A2, group IIA (platelets, synovial fluid)
Background Phospholipase A2 (PLA2) catalyzes the hydrolysis of fatty acids at the sn-2 position of glycerophospholipids. PLA2 (Type V) is a secretory PLA2 (sPLA2) of approximately 14 kDa and is one of the isoforms in the growing list of the PLA2 enzyme family.2 This enzyme, rather than the sPLA2 (Type II), is responsible for arachidonic acid mobilization leading to prostaglandin production in macrophages and mast cells. Consistent with this role, sPLA2 (Type V) is associated with the golgi apparatus, nuclear envelope, and plasma membrane in murine bone marrow-derived mast cells. sPLA2 (Type V) has been cloned from a variety of species including human, mouse, and rat. The enzyme is expressed in heart, lung, placenta, and spleen, as well as P388D1 macrophages and mast cells
Synonyms PLA2G2A; phospholipase A2, group IIA (platelets, synovial fluid); phospholipase A2, membrane associated; GIIC sPLA2; enhancing factor; modifier of Min1; group IIA phospholipase A2; secretory group II phospholipase A2; phosphatidylcholine 2-acylhydrolase 2A; non-pancreatic secreted type II phospholipase A2; EF; Mom1; Pla2; sPLA2; sPla2-IIA
    • Species :
    • Chicken
    • Human
    • Mouse
    • Rat
    • Source :
    • E.coli
    • HEK293
    • Human Cell
    • Insect Cell
    • Mammalian Cell
    • Sf21 Insect Cell
    • Yeast
    • Tag :
    • His
    • GST
    • Myc
    • DDK
    • N/A
    Species Cat.# Product name Source (Host) Tag Protein Length Price
    Rat PLA2G2A-1582R Recombinant Rat PLA2G2A Protein (22-146 aa), His-tagged Yeast His
    Mouse PLA2G2A-522M Recombinant Mouse PLA2G2A Protein, His-tagged Yeast His
    Human PLA2G2A-01H Recombinant Human PLA2G2A HEK293 N/A
    Human PLA2G2A-1031H Recombinant Human PLA2G2A, His-tagged E.coli His
    Human PLA2G2A-1036H Recombinant Human, PLA2G2A His-tagged E.coli His
    Human PLA2G2A-1885H Recombinant Human PLA2G2A Protein, MYC/DDK-tagged HEK293 Myc/DDK
    Human PLA2G2A-2184HCL Recombinant Human PLA2G2A cell lysate Human Cell N/A
    Human PLA2G2A-669H Recombinant Human PLA2G2A protein, His-tagged Insect Cell His
    Human PLA2G2A-900H Recombinant Human PLA2G2A, His tagged Human Cell His
    Mouse PLA2G2A-12888M Recombinant Mouse PLA2G2A Protein Mammalian Cell His
    Mouse Pla2g2a-670M Recombinant Mouse Pla2g2a, His-tagged Sf21 Insect Cell His
    Rat PLA2G2A-4488R Recombinant Rat PLA2G2A Protein Mammalian Cell His
    Rat Pla2g2a-8259R Recombinant Rat Pla2g2a protein, His & GST-tagged E.coli His/GST
    Chicken PLA2G2A-5247C Recombinant Chicken PLA2G2A Mammalian Cell His

    PLA2G2A involved in several pathways and played different roles in them. We selected most pathways PLA2G2A participated on our site, such as Glycerophospholipid metabolism, Ether lipid metabolism, Arachidonic acid metabolism, which may be useful for your reference. Also, other proteins which involved in the same pathway with PLA2G2A were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein
    Glycerophospholipid metabolism PLA2G4A; PLA2G2D; PLD3; MBOAT2; PPAP2CB; ETNK1; PPAP2C; ADPRM; PHYKPL; CHPT1
    Ether lipid metabolism PLD3; PLA2G3; PPAP2A; PLA2G4A; PLD1; PLA2G4F; PAFAH2; PLA2G2F; PLD2; GAL3ST1A
    Arachidonic acid metabolism PLA2G12A; ALOX5B.3; PLA2G4F; CYP4B1; PTGR1; PLA2G4B; CYP2P10; GPX5; PLA2G2E; CYP2AD2
    Linoleic acid metabolism PLA2G4D; CYP2P7; CYP2J2; CYP2C37; PLA2G12A; CYP2C55; PLA2G2A; CYP2C70; DHRS13L1; PLA2G4F
    alpha-Linolenic acid metabolism PLA2G4D; PLA2G4C; PLA2G2E; FADS2; PLA2G4F; ACOX1; PLA2G12A; ACAA1; PLA2G1B; PLA2G2A
    Metabolic pathways MAT2A; GLUD1A; NMNAT2; UGT1A6A; FBP1B; TDO2A; NME4; CEL.1; PNPO; BCMO1
    Ras signaling pathway PLA2G5; PLCG2; MAP2K2; PIK3R5; PLA2G4D; RAP1B; NFKB1; RASA1; FGF12; PDGFRA
    Vascular smooth muscle contraction CALM3A; PRKCBB; CALCRLA; MYH11; ADORA2AB; RHOA; AGTR1A; CALM2B; ROCK2; ADCY1B
    Pancreatic secretion PLCB2; RAB27B; CPB1; GNAQ; KCNMA1; CPA2; RAP1B; ATP2B1; PRSS1; FXYD2
    Fat digestion and absorption PLA2G5; MTTP; PPAP2C; PLA2G2F; PNLIPRP2; SLC27A4; MOGAT2; ABCA1; LIPF; Cel

    PLA2G2A has several biochemical functions, for example, calcium ion binding, calcium-dependent phospholipase A2 activity, phospholipase A2 activity. Some of the functions are cooperated with other proteins, some of the functions could acted by PLA2G2A itself. We selected most functions PLA2G2A had, and list some proteins which have the same functions with PLA2G2A. You can find most of the proteins on our site.

    Function Related Protein
    calcium ion binding ANXA9; JAG2B; NOL3; PLS1; SYT4; FSTL5; ALOX15B; CDHR1; CDH12A; GSNB
    calcium-dependent phospholipase A2 activity PLA2G1B; PLA2G4B; PLA2G5; PLA2G3; PLA2G4F; PLA2G4A; PLA2G2A; PLA2G12A
    phospholipase A2 activity PLA2G12B; PLA2G2A; PLA2G16; PLA2G2E; LCAT; RARRES3; PLA2G10; PLA2G4A; PLB1; PLA2G4AA
    phospholipid binding MTAP1B; PACSIN1A; MYOF; NSFL1C; APOA5; ESYT1; PLA2G15; GRK5; PSD2; APOH

    PLA2G2A has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with PLA2G2A here. Most of them are supplied by our site. Hope this information will be useful for your research of PLA2G2A.

    ALOX12; CRMP1; CRELD2; CEP70

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