• Official Full Name
  • POU class 2 associating factor 1
  • Background
  • Transcriptional coactivator that specifically associates with either OCT1 or OCT2. It boosts the OCT1 mediated promoter activity and to a lesser extent, that of OCT2. It has no intrinsic DNA-binding activity. It recognizes the POU domains of OCT1 and OCT2. It is essential for the response of B-cells to antigens and required for the formation of germinal centers.
  • Synonyms
  • POU2AF1; POU class 2 associating factor 1; POU domain class 2, associating factor 1; POU domain class 2-associating factor 1; OBF1; BOB-1; OCA-B; OCT-binding factor 1; B-cell-specific coactivator OBF-1; POU domain, class 2, associating factor 1; BOB1; OCAB; OBF-1
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human POU2AF1, His-tagged
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human POU2AF1, His-tagged
Source (Host):Mammalian CellsSpecies:Chicken
Product nameRecombinant Chicken POU2AF1
Source (Host):Species:Human
Product nameRecombinant Human POU2AF1 293 Cell Lysate

Protein Function

POU2AF1 has several biochemical functions, for example, DNA binding, protein binding, transcription coactivator activity. Some of the functions are cooperated with other proteins, some of the functions could acted by POU2AF1 itself. We selected most functions POU2AF1 had, and list some proteins which have the same functions with POU2AF1. You can find most of the proteins on our site.
Related Protein
Function DNA binding
Related Protein EXO5; HNRNPU; NKX2.3; TCF4; HIVEP2; SMC1B; NKX2-3; KDM5D; UPF1; ZFP90
Function protein binding
Related Protein IFT43; MED1; FLNA; IRF1; NLRP3; TMEM27; MAPKAPK2; SCN11A; CRYBB1; HSD17B10
Function transcription coactivator activity
Related Protein NR2C2; MED21; HSF2; TCF3; CD3D; MED17; BIRC2; KAT6A; LPIN1; UTF1
Function transcription cofactor activity
Related Protein SND1; CALCOCO1; TMF1; TFDP2; RFXANK; MED17; CREB1; ZFP865; LDB2A; MED13

Interacting Protein

POU2AF1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with POU2AF1 here. Most of them are supplied by our site. Hope this information will be useful for your research of POU2AF1.