ppih
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  • Official Full Name
  • peptidylprolyl isomerase H (cyclophilin H)
  • Background
  • The protein encoded by this gene is a member of the peptidyl-prolyl cis-trans isomerase (PPIase) family. PPIases catalyze the cis-trans isomerization of proline imidic peptide bonds in oligopeptides and accelerate the folding of proteins. This protein is a specific component of the complex that includes pre-mRNA processing factors PRPF3, PRPF4, and PRPF18, as well as U4/U5/U6 tri-snRNP. This protein has been shown to possess PPIase activity and may act as a protein chaperone that mediates the interactions between different proteins inside the spliceosome.
  • Synonyms
  • PPIH; peptidylprolyl isomerase H (cyclophilin H); peptidyl prolyl isomerase H (cyclophilin H); peptidyl-prolyl cis-trans isomerase H; cyclophilin H; CYP 20; CYPH; MGC5016; peptidyl prolyl cis trans isomerase H; PPIase h; rotamase H; small nuclear ribonucleoprotein particle specific cyclophilin H; SnuCyp 20; U snRNP associated cyclophilin SunCyp 20; USA CYP; USA CyP SnuCyp 20; EC 5.2.1.8; Peptidylprolyl isomerase H; PPIH_HUMAN; RGD1564921; Small nuclear ribonucleoprotein particle-specific cyclophilin H; U snRNP associated cyclophilin SnuCyp 20; U-snRNP-associated cyclophilin SnuCyp-20; USA-CYP; USACYP; UsnRNP associated cyclophilin SnuCyp20; USA-CyP SnuCyp-20; U-snRNP-associated cyclophilin SunCyp-20; CYP-20; SnuCyp-20
Cat.#:PPIH-111HTag:N/A
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human Peptidylprolyl Isomerase H
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Cat.#:PPIH-181HTag:HIS
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human PPIH Protein, HIS-tagged
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Cat.#:PPIH-219HTag:T7
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human PPIH protein, T7-tagged
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Cat.#:PPIH-30106THTag:
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human PPIH
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Cat.#:PPIH-30685THTag:T7
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human PPIH, T7 -tagged
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Cat.#:PPIH-3549RTag:His
Source (Host):Mammalian CellsSpecies:Rhesus Macaque
Product nameRecombinant Rhesus monkey PPIH Protein, His-tagged
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Cat.#:PPIH-5245CTag:His
Source (Host):Mammalian CellsSpecies:Chicken
Product nameRecombinant Chicken PPIH
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Cat.#:PPIH-11421ZTag:His
Source (Host):Mammalian CellsSpecies:Zebrafish
Product nameRecombinant Zebrafish PPIH
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Cat.#:PPIH-1980ZTag:His
Source (Host):Mammalian CellsSpecies:Zebrafish
Product nameRecombinant Zebrafish PPIH
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Cat.#:PPIH-2969HCLTag:
Source (Host):Species:Human
Product nameRecombinant Human PPIH 293 Cell Lysate
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Involved Pathway

PPIH involved in several pathways and played different roles in them. We selected most pathways PPIH participated on our site, such as Spliceosome, which may be useful for your reference. Also, other proteins which involved in the same pathway with PPIH were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
Pathway Name
Pathway Related Protein
Spliceosome
AQR; RBM22; SFRS3B; HSPA1A; U2AF2A; PHF5A; THOC3; PRPF31; CRNKL1; HSC70

Protein Function

PPIH has several biochemical functions, for example, cyclosporin A binding, peptidyl-prolyl cis-trans isomerase activity, protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by PPIH itself. We selected most functions PPIH had, and list some proteins which have the same functions with PPIH. You can find most of the proteins on our site.
Function
Related Protein
Function cyclosporin A binding
Related Protein PPIC; PPIE; PPIH; PPID; PPIG; PPIF
Function peptidyl-prolyl cis-trans isomerase activity
Related Protein PPIL2; PPP2R4; PIN4; PPID; FKBP14; FKBP8; PPIAL4B; PPIL4; PPIFB; RANBP2
Function protein binding
Related Protein SLC39A7; PYCARD; TNNT1; PCBD2; DEDD2; CDK5R1; C11orf46; ITGB3B; UBE2C; CENPL
Function ribonucleoprotein complex binding
Related Protein RNASEL; PES1; PIGC; TIMM50; PPIH; CKAP5; PQBP1; PRPF6; RNF135; PES

Interacting Protein

PPIH has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with PPIH here. Most of them are supplied by our site. Hope this information will be useful for your research of PPIH.
PRPF4; N4BP2L2; VCAM1; USP4; SART3; Prpf8; TNIK; USP15; BAG2; PTBP3