PPP1CB Protein, protein phosphatase 1, catalytic subunit, beta isozyme

PPP1CB

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PPP1CB

Official Full Name protein phosphatase 1, catalytic subunit, beta isozyme
Background Type 1 protein Ser/Thr phosphatases (PP1) have a high specific activity against phosphorylase, and are resistant to okadaic acid up to concentrations of 50 nM, but sensitive to Inhibitor-2 and microcystin LR.
Synonyms PPP1CB; protein phosphatase 1, catalytic subunit, beta isozyme; protein phosphatase 1, catalytic subunit, beta isoform; serine/threonine-protein phosphatase PP1-beta catalytic subunit; PP 1B; PP1beta; protein phosphatase 1-beta; protein phosphatase 1-delta; protein phosphatase 1, catalytic subunit, delta isoform; serine/threonine protein phosphatase PP1-beta catalytic subunit; PP-1B; PPP1CD; MGC3672
    • Species :
    • Chicken
    • Human
    • Mouse
    • Rat
    • Rhesus Macaque
    • Zebrafish
    • Source :
    • E.coli
    • HEK293
    • Mammalian Cell
    • Sf9 Insect Cell
    • Tag :
    • GST
    • His
    • N/A
    Species Cat.# Product name Source (Host) Tag Protein Length Price
    Human PPP1CB-2170H Recombinant Human PPP1CB Protein (2-327 aa), His-tagged E.coli His
    Human PPP1CB-1515H Recombinant Human PPP1CB, GST-tagged Sf9 Insect Cell GST
    Human PPP1CB-2949HCL Recombinant Human PPP1CB 293 Cell Lysate HEK293 N/A
    Human PPP1CB-2950HCL Recombinant Human PPP1CB 293 Cell Lysate HEK293 N/A
    Mouse PPP1CB-13210M Recombinant Mouse PPP1CB Protein Mammalian Cell His
    Rat PPP1CB-4612R Recombinant Rat PPP1CB Protein Mammalian Cell His
    Rhesus Macaque PPP1CB-3558R Recombinant Rhesus monkey PPP1CB Protein, His-tagged Mammalian Cell His
    Chicken PPP1CB-6679C Recombinant Chicken PPP1CB Mammalian Cell His
    Zebrafish PPP1CB-1253Z Recombinant Zebrafish PPP1CB Mammalian Cell His

    PPP1CB involved in several pathways and played different roles in them. We selected most pathways PPP1CB participated on our site, such as mRNA surveillance pathway, cGMP-PKG signaling pathway, cAMP signaling pathway, which may be useful for your reference. Also, other proteins which involved in the same pathway with PPP1CB were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein
    mRNA surveillance pathway UPF1; RBM8A; PABPC3; PABPC1B; NCBP1; MSI2A; PPP2R5C; NXT2; PPP2R1B; FIP1L1
    cGMP-PKG signaling pathway IRS4; KCNMB4; NPPB; PPP3CA; NPR2; MAPK1; ATP1A4; NFATC1; ATP1A2; PIK3CD
    cAMP signaling pathway RYR2; NFKBIA; CNGA4; ATP1A3; TSHR; PRKACB; PRKACG; NFATC1; PDE4D; PDE4B
    Oocyte meiosis CAMK2D; SMC1AL; CALM2A; PPP2R5A; PPP3CC; PPP2R5EB; PPP2CB; PPP2R5C; YWHAQA; SMC1A
    Adrenergic signaling in cardiomyocytes ADRB2B; CACNA1SA; PPP2R5C; CAMK2B1; PPP1CA; CREB5; ACTC1; CAMK2G; CALM3A; AGTR1A
    Vascular smooth muscle contraction CALM3B; MAP2K2B; CYP4A14; NPR1; MAP2K1; PLA2G5; CALM2A; CALML3; ADCY1B; CALM
    Hippo signaling pathway RASSF1; PPP2CA; WNT16; TGFB3; CDH1; FGF1; CTNNA2; AJUBA; YWHAH; BMPR1B
    Focal adhesion PAK6B; ITGA8; CAV2; GRB2B; ACTB; COL6A2; BCL2A; FLNC; ERBB2; PDGFC
    Platelet activation ITPR1; ITPR3; MYL12B; ACTB; FERMT3; NOS3; ROCK1; PRKG2; TLN1; FGB
    Long-term potentiation PRKCG; GRIN1; PPP3R2; GRIA2; PRKCA; ITPR1; RPS6KA3; PRKACA; NRAS; CALML3
    Dopaminergic synapse PLCB4; PPP1CB; GNAI3; ATF6B; PPP2CB; SCN1A; GRIA3; CALML3; GNAO1; PPP1CA
    Inflammatory mediator regulation of TRP channels PLCB1; P2RY2; CYP4A14; ALOX12; MAPK12; PIK3R3; PIK3CA; ITPR3; ASIC5; CYP2C50
    Regulation of actin cytoskeleton EZR; FGF10A; FGF17; INS; GNA12; FN1; ITGA2; MYL10; ROCK1; RRAS2
    Insulin signaling pathway PRKAR2AB; TSC1; FOXO1B; SLC2A4; PTPRFB; PHKG1A; KRAS; TRIP10A; RHOQ; RHEB
    Oxytocin signaling pathway PPP1R12A; MYLK2; RCAN1; PPP3R1; ACTB; CAMK1; PPP1CB; Adcy4; HRAS; MYLK4
    Insulin resistance TBC1D4; PTPRFB; NFKBIA; RPS6KA2; PTPN11A; PPARGC1A; SLC2A1A; INSRA; PPP1CB; SLC27A1B
    Amphetamine addiction CAMK2A; DDC; CALM3; DRD1; ATF6B; CREB3L4; FOSB; CAMK2D; CAMK4; CALML5
    Alcoholism GM14479; HIST1H2AC; GRIN1; H2AFY; GRB2; HIST3H2A; GNGT1; HDAC10; GNAO1; MAOA
    Herpes simplex infection IFNA3; FADD; GTF2I; SKP1; FOS; TBPL1; IKBKE; TLR2-2; THOC4; OAS3
    Proteoglycans in cancer PIK3CD; MTOR; SDC4; PPP1R12A; WNT16; GRB2; CCND1; MAP2K1; MAPK11; ACTG1

    PPP1CB has several biochemical functions, for example, metal ion binding, myosin phosphatase activity, myosin-light-chain-phosphatase activity. Some of the functions are cooperated with other proteins, some of the functions could acted by PPP1CB itself. We selected most functions PPP1CB had, and list some proteins which have the same functions with PPP1CB. You can find most of the proteins on our site.

    Function Related Protein
    metal ion binding CYP4F18; INO80B; ZEB2B; CNOT6; FAH; RBM4B; RAB11FIP4A; GIT1; ZNF100; LMO4A
    myosin phosphatase activity PPP1CB
    myosin-light-chain-phosphatase activity PPP1CB
    phosphatase activity PGAM5; PTPN23A; CTDSPL2B; TIGARA; DUSP11; CTDSPLB; PTPN2B; ACPP; PTPN11B; CTDNEP1
    protein binding NDUFA4; USP37; ADRBK1; C3; HESX1; KIR2DL3; TBC1D16; UFD1L; ATP7A; DAB1
    protein kinase binding GRB2; GCSAM; TRIM22; AP1B1; CHEK2; PPP1R12B; CAMK2N2; PTK2; KIF11; CCNE1

    PPP1CB has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with PPP1CB here. Most of them are supplied by our site. Hope this information will be useful for your research of PPP1CB.

    SH2D4A; PPP1R7; PPP1R16A; PPP1R13L; BRCA1; PPP1R12A

    OMAY, SB; NISHIKAWA, M; et al. DECREASED EXPRESSION OF PROTEIN PHOSPHATASE TYPE 2A IN HL-60 VARIANT (HL-6ORA) CELLS RESISTANT TO INDUCTION OF CELL-DIFFERENTIATION BY ALL-TRANS-RETINOIC ACID. EXPERIMENTAL HEMATOLOGY 23:244-251(1995).

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