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PPP1CB

  • Official Full Name

    protein phosphatase 1, catalytic subunit, beta isozyme

  • Overview

    Type 1 protein Ser/Thr phosphatases (PP1) have a high specific activity against phosphorylase, and are resistant to okadaic acid up to concentrations of 50 nM, but sensitive to Inhibitor-2 and microcystin LR.
  • Synonyms

    PPP1CB; protein phosphatase 1, catalytic subunit, beta isozyme; protein phosphatase 1, catalytic subunit, beta isoform; serine/threonine-protein phosphatase PP1-beta catalytic subunit; PP 1B; PP1beta; protein phosphatase 1-beta; protein phosphatase 1-delta; protein phosphatase 1, catalytic subunit, delta isoform; serine/threonine protein phosphatase PP1-beta catalytic subunit; PP-1B; PPP1CD; MGC3672;

  • Recombinant Proteins
  • Cell & Tissue Lysates
  • Protein Pre-coupled Magnetic Beads
  • Chicken
  • Human
  • Mouse
  • Rat
  • Rhesus Macaque
  • Zebrafish
  • E.coli
  • HEK293
  • HEK293T
  • Human cells
  • Mammalian Cell
  • Mammalian cells
  • Sf9 Insect Cell
  • DYKDDDDK
  • Flag
  • GST
  • His
  • His (Fc)
  • Avi
  • Myc
  • DDK
  • N/A
  • N
Species Cat.# Product name Source (Host) Tag Protein Length Price
Human PPP1CB-1515H Active Recombinant Human PPP1CB, GST-tagged Sf9 Insect Cell GST
Human PPP1CB-2949HCL Recombinant Human PPP1CB 293 Cell Lysate HEK293 N/A
Human PPP1CB-2950HCL Recombinant Human PPP1CB 293 Cell Lysate HEK293 N/A
Human PPP1CB-2170H Recombinant Human PPP1CB Protein (2-327 aa), His-tagged E.coli His 2-327 aa
Human PPP1CB-1747H Recombinant Human PPP1CB Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Human PPP1CB-755HFL Recombinant Full Length Human PPP1CB Protein, C-Flag-tagged Mammalian cells Flag
Human PPP1CB-5964H Recombinant Human PPP1CB Protein, Myc/DDK-tagged, C13 and N15-labeled HEK293T Myc/DDK
Human PPP1CB-30H Recombinant Human PPP1CB Protein, DYKDDDDK-tagged Human cells DYKDDDDK
Human PPP1CB-2614H Recombinant Human PPP1CB Protein, His-tagged E.coli N-His Phe45-Arg327
Human PPP1CB-1747H-B Recombinant Human PPP1CB Protein Pre-coupled Magnetic Beads HEK293
Mouse Ppp1cb-5055M Recombinant Mouse Ppp1cb Protein, Myc/DDK-tagged HEK293T Myc/DDK
Mouse PPP1CB-13210M Recombinant Mouse PPP1CB Protein Mammalian Cell His
Mouse PPP1CB-7000M Recombinant Mouse PPP1CB Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Mouse PPP1CB-7000M-B Recombinant Mouse PPP1CB Protein Pre-coupled Magnetic Beads HEK293
Rat PPP1CB-4612R Recombinant Rat PPP1CB Protein Mammalian Cell His
Rat PPP1CB-4271R-B Recombinant Rat PPP1CB Protein Pre-coupled Magnetic Beads HEK293
Rat PPP1CB-4271R Recombinant Rat PPP1CB Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Rhesus Macaque PPP1CB-3558R Recombinant Rhesus monkey PPP1CB Protein, His-tagged Mammalian Cell His
Rhesus Macaque PPP1CB-3376R-B Recombinant Rhesus Macaque PPP1CB Protein Pre-coupled Magnetic Beads HEK293
Rhesus Macaque PPP1CB-3376R Recombinant Rhesus Macaque PPP1CB Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Zebrafish PPP1CB-1253Z Recombinant Zebrafish PPP1CB Mammalian Cell His
Chicken PPP1CB-6679C Recombinant Chicken PPP1CB Mammalian Cell His
  • Involved Pathway
  • Protein Function
  • Interacting Protein
  • PPP1CB Related Articles

PPP1CB involved in several pathways and played different roles in them. We selected most pathways PPP1CB participated on our site, such as mRNA surveillance pathway, cGMP-PKG signaling pathway, cAMP signaling pathway, which may be useful for your reference. Also, other proteins which involved in the same pathway with PPP1CB were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name Pathway Related Protein
mRNA surveillance pathwayUPF1;PPP2R5E;FIP1L1;PABPN1L;EIF4A3;PELO;CASC3;PPP2R5EB;BAT1
cGMP-PKG signaling pathwayCREB3L3;GTF2I;PIK3CA;INS2;PPP3CA;PIK3CD;FXYD2;CREB3L2;GNAQ
cAMP signaling pathwayGRIA4;PIK3R3;MC2R;BRAF;BAD;ATP2B4;MAPK3;GRIN2A;FSHR
Oocyte meiosisPPP1CC;PPP2R5EA;FBXW11A;CALML5;IGF1RB;AURKA;ITPR1;CDC20;ADCY2B
Adrenergic signaling in cardiomyocytesMAPK14A;MAPK3;CREB3;ADRB3A;SCN5A;PIK3R5;PIK3CG;PRKACB;TPMA
Vascular smooth muscle contractionADCY2B;GNA11;PLA2G12B;PRKACBB;GNAS;PPP1CAB;ITPR1;MYL6B;CYP4A14
Hippo signaling pathwayTGFB3;TEAD4;TGFB2;PARD6B;WNT16;BMP8A;FRMD6;APC2;WNT1
Focal adhesionPPP1CA;MYLK3;ITGA11A;KDRL;AKT2;COL6A3;ITGA2B;IGF1RB;HRASA
Platelet activationFERMT3;PIK3CG;AKT2;TBXA2R;PLA2G4A;MAPK1;ROCK1;PPP1CB;PIK3R2
Long-term potentiationGRM5;GNAQ;MAP2K2;ARAF;PPP3CB;PRKACA;PRKACG;PPP3CC;CALM3
Dopaminergic synapseGSK3B;PPP2R2B;MAPK10;GNG10;CLOCK;MAPK12;ARRB2;KIF5B;PLCB3
Inflammatory mediator regulation of TRP channelsPPP1CC;ACCN4;CYP2J6;HTR2B;MAPK9;CALM4;PLCG1;CYP2J5;CYP4A14
Regulation of actin cytoskeletonFN1A;PPP1R12C;PAK6B;ITGA4;FGF3;ITGA1;PTK2AB;PDGFAB;RAC3B
Insulin signaling pathwaySLC2A4;FLOT2;GYS2;FASN;CALM;FOXO1;PPP1R3B;HK3;PIK3R2
Oxytocin signaling pathwayPPP3CC;NPR2;PPP1CC;PLA2G4C;PRKAG1;PRKACG;CACNG8;CALML3;RHOA
Insulin resistancePCK2;PIK3R3A;MGEA5;PPARGC1B;SLC27A4;RPS6KA2;CREB3L2;SLC27A3;NFKB1
AlcoholismHIST1H4D;HIST2H3C2;HIST1H3H;HIST3H3;HIST1H4H;HIST1H2AN;HIST1H2BA;HIST1H3D;HIST1H2BO
Herpes simplex infectionTRAF3;HLA-DOA;PILRA;SKP1;PVRL1B;DAXX;GLTSCR2;PPP1CB;EIF2AK2
Proteoglycans in cancerIL12B;ROCK2;NANOG;MAP2K1;CAMK2B;RPS6KB1;ITGB1;ITGB5;FZD1

PPP1CB has several biochemical functions, for example, metal ion binding, myosin phosphatase activity, myosin-light-chain-phosphatase activity. Some of the functions are cooperated with other proteins, some of the functions could acted by PPP1CB itself. We selected most functions PPP1CB had, and list some proteins which have the same functions with PPP1CB. You can find most of the proteins on our site.

Function Related Protein
metal ion bindingARMC1L;COL9A1;KDM3B;ZFPL1;ZFP330;ZNF530;CNOT6L;ZNF124;NRXN2A
myosin phosphatase activity
myosin-light-chain-phosphatase activity
phosphatase activityDUSP28;ACPL2;CTDSPL2B;DUSP22B;MTMR7A;CTDSPL2A;MTMR1B;PTPN23A;DUSP19A
protein bindingBTF3;TINF2;SIN3A;TNNT1;MAGED1;FAM200A;CD276;CAMK2A;VEGFAA
protein kinase bindingXBP1;CCNL1B;TELO2;BCL10;MAG;KCNA5;CCND3;HDAC4;IKBKB

PPP1CB has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with PPP1CB here. Most of them are supplied by our site. Hope this information will be useful for your research of PPP1CB.

SH2D4A; PPP1R7; PPP1R16A; PPP1R13L; BRCA1; PPP1R12A

OMAY, SB; NISHIKAWA, M; et al. DECREASED EXPRESSION OF PROTEIN PHOSPHATASE TYPE 2A IN HL-60 VARIANT (HL-6ORA) CELLS RESISTANT TO INDUCTION OF CELL-DIFFERENTIATION BY ALL-TRANS-RETINOIC ACID. EXPERIMENTAL HEMATOLOGY 23:244-251(1995).
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