PPP1R17 Protein, protein phosphatase 1, regulatory subunit 17

PPP1R17

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PPP1R17

Official Full Name protein phosphatase 1, regulatory subunit 17
Background The protein encoded by this gene is found primarily in cerebellar Purkinje cells, where it functions as a protein phosphatase inhibitor. The encoded protein is a substrate for cGMP-dependent protein kinase. An allele of this gene was discovered that increases susceptibility to hypercholesterolemia. Two transcript variants encoding different isoforms have been found for this gene.
Synonyms chromosome 7 open reading frame 16; GSBS; G-substrate; OTTHUMP00000158793; OTTHUMP00000202600
    • Species :
    • Human
    • Mouse
    • Source :
    • HEK293
    • Mammalian Cell
    • Wheat Germ
    • Tag :
    • GST
    • His
    • N/A
    Species Cat.# Product name Source (Host) Tag Protein Length Price
    Human PPP1R17-0134H Recombinant Human PPP1R17 Protein, GST-Tagged Wheat Germ GST
    Human PPP1R17-7974HCL Recombinant Human C7orf16 293 Cell Lysate HEK293 N/A
    Mouse PPP1R17-13226M Recombinant Mouse PPP1R17 Protein Mammalian Cell His

    PPP1R17 involved in several pathways and played different roles in them. We selected most pathways PPP1R17 participated on our site, such as Long-term depression, which may be useful for your reference. Also, other proteins which involved in the same pathway with PPP1R17 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein
    Long-term depression GNAQ; PPP2CB; RYR1; MAP2K1; PPP1R17; PRKG2; BRAF; GNAI3; GUCY1A3; PLCB4

    PPP1R17 has several biochemical functions, for example, protein serine/threonine phosphatase inhibitor activity. Some of the functions are cooperated with other proteins, some of the functions could acted by PPP1R17 itself. We selected most functions PPP1R17 had, and list some proteins which have the same functions with PPP1R17. You can find most of the proteins on our site.

    Function Related Protein
    protein serine/threonine phosphatase inhibitor activity PPP1R17; PPP1R8; PPP1R1C; PPP1R1A; PPP1R11; PPP1R14C

    PPP1R17 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with PPP1R17 here. Most of them are supplied by our site. Hope this information will be useful for your research of PPP1R17.

    Iizuka, M; Murata, T; et al. Increased contractility of hepatic stellate cells in cirrhosis is mediated by enhanced Ca2+-dependent and Ca2+-sensitization pathways. AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY 300:G1010-G1021(2011).
    Murthy, KS; Zhou, HP; et al. Differential signalling by muscarinic receptors in smooth muscle: m2-mediated inactivation of myosin light chain kinase via G(i3), Cdc42/Rac1 and p21-activated kinase 1 pathway, and m3-mediated MLC20 (20 kDa regulatory light chain of myosin II) phosphorylation via Rho-associated kinase/myosin phosphatase targeting subunit 1 and protein kinase C/CPI-17 pathway. BIOCHEMICAL JOURNAL 374:145-155(2003).

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