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PPP2CB

  • Official Full Name

    protein phosphatase 2, catalytic subunit, beta isozyme

  • Overview

    This gene encodes the phosphatase 2A catalytic subunit. Protein phosphatase 2A is one of the four major Ser/Thr phosphatases, and it is implicated in the negative control of cell growth and division. It consists of a common heteromeric core enzyme, which is composed of a catalytic subunit and a constant regulatory subunit, that associates with a variety of regulatory subunits. This gene encodes a beta isoform of the catalytic subunit.
  • Synonyms

    PPP2CB; protein phosphatase 2, catalytic subunit, beta isozyme; protein phosphatase 2 (formerly 2A), catalytic subunit, beta isoform; serine/threonine-protein phosphatase 2A catalytic subunit beta isoform; PP2Abeta; protein phosphatase 2A catalytic subunit; beta isoform; PP2A beta; PP2A-beta; PP2AB_HUMAN; PP2CB; Protein phosphatase 2 catalytic subunit beta isozyme; Protein phosphatase 2, catalytic subunit, beta isoform; Protein phosphatase 2A catalytic subunit beta isoform; Protein phosphatase type 2A catalytic subunit; Serine/threonine protein phosphatase 2A catalytic subunit beta; OTTHUMP00000225455; protein phosphatase 2A catalytic subunit, beta isoform; serine/threonine protein phosphatase 2A, catalytic subunit, beta isoform;

  • Recombinant Proteins
  • Cell & Tissue Lysates
  • Protein Pre-coupled Magnetic Beads
  • Chicken
  • Human
  • Mouse
  • Rat
  • Rhesus Macaque
  • Zebrafish
  • E.coli
  • HEK293
  • In Vitro Cell Free System
  • Mammalian Cell
  • Wheat Germ
  • GST
  • His
  • His (Fc)
  • Avi
  • N/A
  • N
Species Cat.# Product name Source (Host) Tag Protein Length Price
Human PPP2CB-650H Recombinant Human PPP2CB Protein, His-tagged E.coli His
Human PPP2CB-27931TH Recombinant Human PPP2CB Wheat Germ N/A 309 amino acids
Human PPP2CB-2927HCL Recombinant Human PPP2CB 293 Cell Lysate HEK293 N/A
Human PPP2CB-2928HCL Recombinant Human PPP2CB 293 Cell Lysate HEK293 N/A
Human PPP2CB-1178H Recombinant Human PPP2CB Protein (1-309 aa), GST-tagged E.coli GST 1-309 aa
Human PPP2CB-2620H Recombinant Human PPP2CB Protein, His-tagged E.coli N-His Met1-Leu309
Human PPP2CB-410HF Recombinant Full Length Human PPP2CB Protein In Vitro Cell Free System 309 amino acids
Mouse PPP2CB-13250M Recombinant Mouse PPP2CB Protein Mammalian Cell His
Mouse PPP2CB-7030M Recombinant Mouse PPP2CB Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Mouse PPP2CB-7030M-B Recombinant Mouse PPP2CB Protein Pre-coupled Magnetic Beads HEK293
Rat PPP2CB-4632R Recombinant Rat PPP2CB Protein Mammalian Cell His
Rat PPP2CB-4291R Recombinant Rat PPP2CB Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Rat PPP2CB-4291R-B Recombinant Rat PPP2CB Protein Pre-coupled Magnetic Beads HEK293
Rhesus Macaque PPP2CB-3570R Recombinant Rhesus monkey PPP2CB Protein, His-tagged Mammalian Cell His
Rhesus Macaque PPP2CB-3388R-B Recombinant Rhesus Macaque PPP2CB Protein Pre-coupled Magnetic Beads HEK293
Rhesus Macaque PPP2CB-3388R Recombinant Rhesus Macaque PPP2CB Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Zebrafish PPP2CB-12481Z Recombinant Zebrafish PPP2CB Mammalian Cell His
Chicken PPP2CB-6681C Recombinant Chicken PPP2CB Mammalian Cell His
  • Involved Pathway
  • Protein Function
  • Interacting Protein
  • PPP2CB Related Research Area

PPP2CB involved in several pathways and played different roles in them. We selected most pathways PPP2CB participated on our site, such as mRNA surveillance pathway, Sphingolipid signaling pathway, Oocyte meiosis, which may be useful for your reference. Also, other proteins which involved in the same pathway with PPP2CB were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name Pathway Related Protein
mRNA surveillance pathwayPPP2R2BB;GSPT1L;PPP1CAB;CSTF2T;NXF2;PPP2R5C;PNN;UPF1;SMG1
Sphingolipid signaling pathwayPPP2CB;PPP2R5B;MAPK10;PPP2R5A;S1PR4;PLD1;PIK3CB;SPHK2;ROCK1
Oocyte meiosisYWHAZ;SGOL1;PPP2R5C;PPP3R2;PPP2R5EA;CAMK2D2;CAMK2D1;CALM3;CALM4
PIK-Akt signaling pathwayPTEN;PHLPP2;MAPK1;IL2RA;FGF12;GNGT1;PPP2R5A;INSR;COL6A6
AMPK signaling pathwayScd1;PFKL;CRTC2;CREB3L1;CD36;FOXO1;CFTR;CCNA2;SLC2A4
Adrenergic signaling in cardiomyocytesFXYD2;CREB3L1;TPM1;ATP1A3;PPP2R2A;MYH7;SCN5A;CACNG6;ADCY6
TGF-beta signaling pathwayCUL1B;BMP2B;BMP5;LTBP1;ID3;ACVR1;E2F5;ACVR1L;BMP2
Hippo signaling pathwayWNT7A;WNT3;DVL3;NF2;CTGF;PRKCI;DLG3;TEAD3;WTIP
Tight junctionCLDN22;MYL2B;AKT2L;OCLNA;CLDN15;CSDA;CLDN3;PPP2R2D;MPP5A
Dopaminergic synapsePRKACB;PLCB2;CREB5;PPP2R5C;ITPR1;GRIA1;CAMK2D;ARNTL;KIF5A
Long-term depressionPRKCB;MAP2K1;NRAS;PLCB2;GNAQ;PLCB3;LYN;PRKG2;PLCB1
Chagas disease (American trypanosomiasis)C1QC;GNAI1;PPP2CA;PPP2R1A;GNAI3;MAPK11;C1QB;NFKBIA;IL1B
Hepatitis CRELA;NR1H3;NFKBIA;IL-8;SCARB1;IRF1;CLDN4;IFNA10;HRAS

PPP2CB has several biochemical functions, for example, metal ion binding, protein C-terminus binding, protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by PPP2CB itself. We selected most functions PPP2CB had, and list some proteins which have the same functions with PPP2CB. You can find most of the proteins on our site.

Function Related Protein
metal ion bindingZNF398;ZFP687;FTR43;ZFP518A;SAP30;ZNF501;ZNFL2A;ANGPT2;ATP2B3B
protein C-terminus bindingZBTB16;AGO2;DAB2;C11orf60;NIPBL;NCF2;KCNJ11;MIF4GD;CEP120
protein bindingBCL11B;COL6A2;FAM129A;NIPBL;HAT1;TXNDC9;UQCC1;GEMIN7;DDX42
contributes_to protein serine/threonine phosphatase activityPPP2CB;CYCS

PPP2CB has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with PPP2CB here. Most of them are supplied by our site. Hope this information will be useful for your research of PPP2CB.

PPP2R1A; IGBP1; AXIN2; TCP1; CCT6A

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