ppp3r2
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  • Official Full Name
  • protein phosphatase 3, regulatory subunit B, beta
  • Background
  • Calcineurin subunit B type 2 is a protein that in humans is encoded by the PPP3R2 gene.
  • Synonyms
  • PPP3R2; protein phosphatase 3, regulatory subunit B, beta; protein phosphatase 3 (formerly 2B), regulatory subunit B (19kD), beta isoform (calcineurin B, type II) , protein phosphatase 3 (formerly 2B), regulatory subunit B, 19kDa, beta isoform (calcineurin B, type II) , protein phosphatase 3 (formerly 2B), reg; calcineurin subunit B type 2; calcineurin B; type II (19kDa); PPP3RL; protein phosphatase 2B regulatory subunit 2; protein phosphatase 3; regulatory subunit B (calcineurin B) like; Calcineurin B like protein; Calcineurin B type II (19kDa); Calcineurin B type II; Calcineurin B-like protein; Calcineurin BII; Calcineurin subunit B isoform 2; CANB2_HUMAN; CBLP; CBLP like; CNBII; PPP3R1-like; Protein phosphatase 3 (formerly 2B) regulatory subunit B (19kD) beta isoform (calcineurin B type II); Protein phosphatase 3 (formerly 2B) regulatory subunit B beta isoform; Protein phosphatase 3 regulatory subunit B (19kD) beta isoform (calcineurin B type II); Protein phosphatase 3 regulatory subunit B (calcineurin B) like; Protein phosphatase 3 regulatory subunit B beta; Protein phosphatase 3 regulatory subunit B beta isoform; OTTHUMP00000021813; calcineurin B, type II (19kDa)
Cat.#:PPP3R2-973HTag:His
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human Protein Phosphatase 3, Regulatory Subunit B, His-tagged
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Cat.#:PPP3R2-1924HTag:GST
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human PPP3R2, GST-tagged
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Cat.#:PPP3R2-29542THTag:His
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human PPP3R2, His-tagged
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Cat.#:PPP3R2-4642RTag:His
Source (Host):Mammalian CellsSpecies:Rat
Product nameRecombinant Rat PPP3R2 Protein
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Cat.#:PPP3R2-2912HCLTag:
Source (Host):Species:Human
Product nameRecombinant Human PPP3R2 293 Cell Lysate
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Involved Pathway

PPP3R2 involved in several pathways and played different roles in them. We selected most pathways PPP3R2 participated on our site, such as MAPK signaling pathway, Calcium signaling pathway, cGMP-PKG signaling pathway, which may be useful for your reference. Also, other proteins which involved in the same pathway with PPP3R2 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
Pathway Name
Pathway Related Protein
MAPK signaling pathway
MAPK12A; TGFBR2; CACNG1; RPS6KA2; GADD45G; FGF10A; MAPK3; ATF4; CACNA1C; MAP3K1
Calcium signaling pathway
ERBB3B; PRKACAB; TACR3L; GNA11A; ORAI1; HTR2A; PPP3CB; CAMK2A; CALM2A; GNA15.4
cGMP-PKG signaling pathway
NFATC4; CALM1; BDKRB2; ITPR1; KCNJ8; GNAQ; VDAC3; ATP2A3; NFATC3; ATP1B4
Oocyte meiosis
PPP2CA; CALML3; PPP3R1; CDC25C; CALM3B; PRKACAB; PRKACA; CPEB1B; PPP2R1A; MAD2L1
Apoptosis
FAS; DBNL; STK24; PRKACBB; PIK3R2; CTNNB2; BOKA; ATM; PLEC; PRKAR2AB
Wnt signaling pathway
LRP5; WNT2; MAPK8; FZD3B; PORCN; FZD9B; GPC4; PRKCG; WIF1; PPP3CCB
Axon guidance
DLG3; DUSP5; DUSP1; CRMP1; SEMA3AA; ROCK2; PAK2; PTPRA; JAK1; DPYSL2
VEGF signaling pathway
PIK3R2; MAPK13; SRC; MAP2K2; PRKCB; PPP3R2; AKT3A; MAPKAPK3; SH2D2A; NOS3
Osteoclast differentiation
FOSL1; PPP3R1; TEC; MAP3K14; PPP3CA; CYBA; IFNGR1; PIK3R1; LILRB4; SFPI1
Natural killer cell mediated cytotoxicity
KIR2DL1; PPP3CC; MICA; PIK3CG; MAPK1; IFNA17; PTPN11; RAC2; NFATC1; BRAF
T cell receptor signaling pathway
LCK; VAV1; MAPK13; FOS; CD8A; DBNLB; DLG1; MAP2K7; CBL; ICOS
B cell receptor signaling pathway
HDAC5; TTC6; DUSP4; CDK7; LCP2A; PIK3CA; PIK3AP1; RAP2A; PLEKHA1; PIK3CG
Long-term potentiation
PPP1CA; GRIN2B; MAP2K1; CALML3; PPP3CB; ARAF; PPP1R1A; CALM3; PLCB4; PRKCA
Glutamatergic synapse
PPP3CA; GNG8; PRKACG; GNG11; SHANK3; ADRBK2; SLC1A1; Adcy4; GRIN3B; SLC1A7
Oxytocin signaling pathway
PLA2G4C; CACNA2D3; CACNG7; MYLK3; MAPK7; CAMK2A; RYR1; RYR2; KRAS; PIK3R1
Glucagon signaling pathway
SLC2A2; PLCB4; PYGB; CREB3L1; G6PC; G6PC2; FBP1; PRKAG1; GNAS; EP300
Renin secretion
PDE1B; PPP3R2; PTGER4; PRKACG; CALML5; PTGER2; PPP3CB; Ren1; GNAI3; NPR1
Alzheimers disease
NDUFAB1; NDUFA2; COX8C; NDUFB6; ATP5F1; ATP5D; CAPN1; COX4I2; GRIN2B; UQCRH
Amyotrophic lateral sclerosis (ALS)
TOMM40L; TNFRSF1B; GRIN1; RAC1; TNF; GPX1; DAXX; TRP53; GRIA1; TOMM40
Amphetamine addiction
PPP3CA; PPP3CB; CALML5; CREB5; PPP1CC; CAMK2B; CAMK2D; GRIN2D; GNAS; GRIA3
Tuberculosis
ARHGEF12; IFNA8; CALM4; FCGR3; CAP18; Casp3; IFNA4; MAPK10; HLA-DRA; LAMP2
HTLV-I infection
FZD2; FZD8; XPO1; HLA-DRB1; KRAS; RELA; ANAPC11; MAP3K3; STAT5B; HLA-C

Protein Function

PPP3R2 has several biochemical functions, for example, calcium ion binding, protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by PPP3R2 itself. We selected most functions PPP3R2 had, and list some proteins which have the same functions with PPP3R2. You can find most of the proteins on our site.
Function
Related Protein
Function calcium ion binding
Related Protein DGKB; PLA2G4B; DAG1; SYT12; RPH3A; PCDH12; APCS; NCALDA; SLC25A12; NINL
Function protein binding
Related Protein CLNS1A; ARFIP2; ACTR8; SMU1; FAM128B; DRD4; ZSCAN21; SNX17; SAMD4A; UPK3A

Interacting Protein

PPP3R2 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with PPP3R2 here. Most of them are supplied by our site. Hope this information will be useful for your research of PPP3R2.
TFCP2; AURKA; BUB1; CD14; CCND1; APC; MSH2; PTPN12; PTPRJ; SMAD4; PDGFRL; FBXW7; DLC1; MLH3

PPP3R2 Related Articles

Fleming, I; Busse, R; et al. Tyrosine phosphorylation and bradykinin-induced signaling in endothelial cells. AMERICAN JOURNAL OF CARDIOLOGY 80:A102-A109(1997).
Csortos, C; Zolnierowicz, S; et al. High complexity in the expression of the B' subunit of protein phosphatase 2A(0) - Evidence for the existence of at least seven novel isoforms. JOURNAL OF BIOLOGICAL CHEMISTRY 271:2578-2588(1996).