ppp3r2
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  • Official Full Name
  • protein phosphatase 3, regulatory subunit B, beta
  • Background
  • Calcineurin subunit B type 2 is a protein that in humans is encoded by the PPP3R2 gene.
  • Synonyms
  • PPP3R2; protein phosphatase 3, regulatory subunit B, beta; protein phosphatase 3 (formerly 2B), regulatory subunit B (19kD), beta isoform (calcineurin B, type II) , protein phosphatase 3 (formerly 2B), regulatory subunit B, 19kDa, beta isoform (calcineurin B, type II) , protein phosphatase 3 (formerly 2B), reg; calcineurin subunit B type 2; calcineurin B; type II (19kDa); PPP3RL; protein phosphatase 2B regulatory subunit 2; protein phosphatase 3; regulatory subunit B (calcineurin B) like; Calcineurin B like protein; Calcineurin B type II (19kDa); Calcineurin B type II; Calcineurin B-like protein; Calcineurin BII; Calcineurin subunit B isoform 2; CANB2_HUMAN; CBLP; CBLP like; CNBII; PPP3R1-like; Protein phosphatase 3 (formerly 2B) regulatory subunit B (19kD) beta isoform (calcineurin B type II); Protein phosphatase 3 (formerly 2B) regulatory subunit B beta isoform; Protein phosphatase 3 regulatory subunit B (19kD) beta isoform (calcineurin B type II); Protein phosphatase 3 regulatory subunit B (calcineurin B) like; Protein phosphatase 3 regulatory subunit B beta; Protein phosphatase 3 regulatory subunit B beta isoform; OTTHUMP00000021813; calcineurin B, type II (19kDa)
Cat.#:PPP3R2-973HTag:His
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human Protein Phosphatase 3, Regulatory Subunit B, His-tagged
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Cat.#:PPP3R2-1924HTag:GST
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human PPP3R2, GST-tagged
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Cat.#:PPP3R2-29542THTag:His
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human PPP3R2, His-tagged
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Cat.#:PPP3R2-4642RTag:His
Source (Host):Mammalian CellsSpecies:Rat
Product nameRecombinant Rat PPP3R2 Protein
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Cat.#:PPP3R2-2912HCLTag:
Source (Host):Species:Human
Product nameRecombinant Human PPP3R2 293 Cell Lysate
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Involved Pathway

PPP3R2 involved in several pathways and played different roles in them. We selected most pathways PPP3R2 participated on our site, such as MAPK signaling pathway, Calcium signaling pathway, cGMP-PKG signaling pathway, which may be useful for your reference. Also, other proteins which involved in the same pathway with PPP3R2 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
Pathway Name
Pathway Related Protein
MAPK signaling pathway
CACNB3; Casp3; GNA12A; HRASB; BRAF; NGF; FGF8A; NTF3; NFATC1; GADD45BA
Calcium signaling pathway
CHRM5A; SLC25A31; PHKA1; TNNC1; EDNRAA; PRKACAA; PHKB; EDNRB; STIM2; ADRa1A
cGMP-PKG signaling pathway
PRKCE; CALM1; KCNMB4; PDE5A; KCNJ8; MAPK1; ATP1A1; ITPR3; SLC8A1; RHOA
Oocyte meiosis
YWHAQA; PLCZ1; CALM1A; PPP1R2P9; RPS6KA3B; YWHABA; PRKACG; FBXW11B; CUL1A; ANAPC4
Apoptosis
PRKACA; HIST1H1C; PIK3CB; CASP8L1; CTNNB2; IRF6; DIABLOB; TNFRSF10C; IL1B; OCLN
Wnt signaling pathway
CER1; NKD2; FZD3A; TCF7; WNT5A; PPP3CB; PRKCB; RAC1; FRAT2; GSK3B
Axon guidance
SEMA7A; KRAS; EPHA10; GDNF; CSF2RA; Unc5b; CSF2RB; PLXNA3; NTN1B; CSF2
VEGF signaling pathway
RAC2; PLA2G4AA; HRASA; PIK3R5; AKT2; PIK3CA; AKT2L; MAPK1; PLA2G4A; MAPK12A
Osteoclast differentiation
LILRA4; TNFRSF11B; LILRB3; NFKB1; PIK3R5; CYBA; CALCR; MAP3K14; GAB2; PPARG
Natural killer cell mediated cytotoxicity
RAET1E; FASLG; CD244; LCP2; TNFSF10; FCGR3B; Casp3; MAP2K1; IFNA1; ULBP1
T cell receptor signaling pathway
IKBKG; PIK3CA; PIK3CB; NCK2; LCK; NFKB1; PLCG1; HRAS; GRAP2; CBL
B cell receptor signaling pathway
LAT2; INPP5D; INPPL1; PRKCB; TTC6; cgr2b; PIK3R1; PIK3CD; PTPN6; BTK
Long-term potentiation
GRM1; GRIA2; ARAF; PPP1CC; RPS6KA3; GRIN2C; PRKCA; GRIN2B; PRKACA; PPP3CA
Glutamatergic synapse
PPP3R1; GNAI3; PRKCG; GRM2; GNG4; GNG3; GRIK1; GRM6; GNAS; SLC1A6
Oxytocin signaling pathway
PRKAG1; PPP1CB; MYL9; CACNA2D4; PIK3CA; ACTB; PPP3R1; ITPR1; RAF1; PRKCG
Glucagon signaling pathway
PRKACB; PPP3CC; FOXO1; PLCB4; CAMK2B; GYS1; PKM2; PYGM; PHKB; PDHB
Renin secretion
ITPR1; CALM1; CLCA1; PTGER4; PDE1A; ORAI1; AGTR1B; PRKG2; CLCA3; CALM2
Alzheimers disease
CDK5R1; NDUFB3; mt-Atp8; NDUFC2-KCTD14; CHP; COX6B2; NDUFB1; GRIN2C; CALM3; ATP5H
Amyotrophic lateral sclerosis (ALS)
CASP1; PPP3CB; Casp3; CYCS; GRIA2; DERL1; TP53; NEFH; PPP3CA; TRP53
Amphetamine addiction
SLC18A2; CREB3L2; GRIN3A; PPP1CC; ATF6B; CALM2; SLC14A2; GRIA3; CREB3; PPP3CA
Tuberculosis
BID; TLR1; MAPK13; CAMK2D; ITGB2; TLR9; TNF; Ifna15; ARHGEF12; ATP6AP1
HTLV-I infection
ITGAL; AKT2; ATF3; PIK3CA; MSX2; LTBR; NFKB2; CD3D; TP53INP1; TNFRSF1A

Protein Function

PPP3R2 has several biochemical functions, for example, calcium ion binding, protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by PPP3R2 itself. We selected most functions PPP3R2 had, and list some proteins which have the same functions with PPP3R2. You can find most of the proteins on our site.
Function
Related Protein
Function calcium ion binding
Related Protein CAPSLA; FKBP14; PCDH12; NOTCH1; PLA2G12B; HPCAL4; GM5077; PCDHGA8; PLSCR4; PLCB1
Function protein binding
Related Protein TMEM106B; ALPL; CTLA4; HOXB9; TERF1; HYLS1; RNF5; EDARADD; MEIOB; TRIM29

Interacting Protein

PPP3R2 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with PPP3R2 here. Most of them are supplied by our site. Hope this information will be useful for your research of PPP3R2.
TFCP2; AURKA; BUB1; CD14; CCND1; APC; MSH2; PTPN12; PTPRJ; SMAD4; PDGFRL; FBXW7; DLC1; MLH3

PPP3R2 Related Articles

Fleming, I; Busse, R; et al. Tyrosine phosphorylation and bradykinin-induced signaling in endothelial cells. AMERICAN JOURNAL OF CARDIOLOGY 80:A102-A109(1997).
Csortos, C; Zolnierowicz, S; et al. High complexity in the expression of the B' subunit of protein phosphatase 2A(0) - Evidence for the existence of at least seven novel isoforms. JOURNAL OF BIOLOGICAL CHEMISTRY 271:2578-2588(1996).