ppp3r2
Share
  • Official Full Name
  • protein phosphatase 3, regulatory subunit B, beta
  • Background
  • Calcineurin subunit B type 2 is a protein that in humans is encoded by the PPP3R2 gene.
  • Synonyms
  • PPP3R2; protein phosphatase 3, regulatory subunit B, beta; protein phosphatase 3 (formerly 2B), regulatory subunit B (19kD), beta isoform (calcineurin B, type II) , protein phosphatase 3 (formerly 2B), regulatory subunit B, 19kDa, beta isoform (calcineurin B, type II) , protein phosphatase 3 (formerly 2B), reg; calcineurin subunit B type 2; calcineurin B; type II (19kDa); PPP3RL; protein phosphatase 2B regulatory subunit 2; protein phosphatase 3; regulatory subunit B (calcineurin B) like; Calcineurin B like protein; Calcineurin B type II (19kDa); Calcineurin B type II; Calcineurin B-like protein; Calcineurin BII; Calcineurin subunit B isoform 2; CANB2_HUMAN; CBLP; CBLP like; CNBII; PPP3R1-like; Protein phosphatase 3 (formerly 2B) regulatory subunit B (19kD) beta isoform (calcineurin B type II); Protein phosphatase 3 (formerly 2B) regulatory subunit B beta isoform; Protein phosphatase 3 regulatory subunit B (19kD) beta isoform (calcineurin B type II); Protein phosphatase 3 regulatory subunit B (calcineurin B) like; Protein phosphatase 3 regulatory subunit B beta; Protein phosphatase 3 regulatory subunit B beta isoform; OTTHUMP00000021813; calcineurin B, type II (19kDa)
Cat.#:PPP3R2-973HTag:His
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human Protein Phosphatase 3, Regulatory Subunit B, His-tagged
+Inquiry
Cat.#:PPP3R2-1924HTag:GST
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human PPP3R2, GST-tagged
+Inquiry
Cat.#:PPP3R2-29542THTag:His
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human PPP3R2, His-tagged
+Inquiry
Cat.#:PPP3R2-4642RTag:His
Source (Host):Mammalian CellsSpecies:Rat
Product nameRecombinant Rat PPP3R2 Protein
+Inquiry
Cat.#:PPP3R2-2912HCLTag:N/A
Source (Host):Species:Human
Product nameRecombinant Human PPP3R2 293 Cell Lysate
+Inquiry

Involved Pathway

PPP3R2 involved in several pathways and played different roles in them. We selected most pathways PPP3R2 participated on our site, such as MAPK signaling pathway, Calcium signaling pathway, cGMP-PKG signaling pathway, which may be useful for your reference. Also, other proteins which involved in the same pathway with PPP3R2 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
Pathway Name
Pathway Related Protein
MAPK signaling pathway
MAP3K1; MAPK3; GADD45AA; MAP4K2; FGF11A; PLA2G4AA; PLA2G4C; Pdgfa&Pdgfb; FGF1B; MINK1
Calcium signaling pathway
ITPKC; SPHK2; PLCZ1; SLC25A4; ITPKA; ADORA2B; P2RX3A; CACNA1C; TACR1; Adcy4
cGMP-PKG signaling pathway
KCNJ8; ATP1B4; PIK3CG; PDE3A; IRS1; MEF2A; PIK3CB; IRS4; ATP1B2; ATP1A3
Oocyte meiosis
BUB1; YWHAB; SMC1AL; SPDYA; CAMK2D1; PRKACAA; YWHABB; PPP3R1B; PTTG1; PPP3CCA
Apoptosis
NGF; DNM1L; DFFA; CAPN2A; TRADD; IKBKB; BNIP3L; CAPN2L; BAXA; PIK3CD
Wnt signaling pathway
NFATC2; CSNK1A1L; CSNK2A2A; CAMK2D1; GPC4; PRKCBB; SFRP2; TBL1Y; NLK1; ROCK2
Axon guidance
LIMK1; DUSP6; PAK4; RND1L; SPRED1; DAB2IPB; GFRA2; SEMA3G; ROBO1; PAQR3B
VEGF signaling pathway
SPHK2; PPP3R2; MAPK11; PPP3CB; RAC3B; PLCG2; PRKCBB; SHC2; PPP3CCB; CDC42L
Osteoclast differentiation
SIRPB1; LILRB5; GRB2; SFPI1; NFKBIA; IL1A; TGFB2; SOCS3; IL1R1; IL1B
Natural killer cell mediated cytotoxicity
CD48; KIR2DL4; IFNA4; NCR2; PPP3CC; KLRC2; NRAS; SAMD3; HLA-A; PPP3R2
T cell receptor signaling pathway
CD3E; CD3E; CD3D; MUC1; VAV1; PTPRC; NFATC3; IL5; ICOS; FYN; PPP3CA
B cell receptor signaling pathway
BCL2L11; VAV2; BLK; HRAS; MAPK1; VAV3; PLEKHA1; BANK1; HDAC5; DOK1B
Long-term potentiation
PPP3R2; PPP3R1; CALML5; GNAQ; PLCB2; MAP2K1; RPS6KA6; CALM2; PRKCG; CAMK2B
Glutamatergic synapse
PRKCB; GRIN2B; GRIK2; MAPK1; GRIN3B; MAPK3; PLCB3; GRM6; PRKCA; GNB4
Oxytocin signaling pathway
RAF1; CAMKK1; PPP1CB; NFATC4; RGS2; ROCK2; PIK3R2; CCND1; RCAN1; RYR3
Glucagon signaling pathway
GCG; EP300; SLC2A2; LDHAL6B; ACACB; GCGR; SLC2A1; PHKA1; GNAS; PPP3CB
Renin secretion
CALM3; GNAS; PDE1A; REN; PLCB4; GNAI3; CLCA2; ORAI1; NPR1; CALML3
Alzheimers disease
COX5A; GSK3B; NDUFB5; COX6A1; CYCS; NDUFB8; FAS; NDUFA9; ERN1; CALM2
Amyotrophic lateral sclerosis (ALS)
MAPK14; GRIA1; GRIA2; TNF; ALS2; MAPK11; GRIN2A; BAX; CAT; PRPH
Amphetamine addiction
CAMK2A; CREB5; DDC; GRIA1; SLC14A2; SIRT1; PRKACG; PRKACA; ARC; GRIN2B
Tuberculosis
PPP3CC; TGFB3; FCGR3A; NFYB; ITGB2L; HLA-DMA; Pla2r1; RHOA; NFYA; IRAK1
HTLV-I infection
WNT8A; APC2; WNT9A; SRF; CRTC1; WNT8B; WNT2; WNT5B; LTA; WNT16

Protein Function

PPP3R2 has several biochemical functions, for example, calcium ion binding, protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by PPP3R2 itself. We selected most functions PPP3R2 had, and list some proteins which have the same functions with PPP3R2. You can find most of the proteins on our site.
Function
Related Protein
Function calcium ion binding
Related Protein Shh; MGMT; PNLIPRP1; ANXA1A; PCDH1G31; PLA2G2E; MATN3; CRNN; VSNL1A; PCDH2AB3
Function protein binding
Related Protein STIM2; RBBP8; AXIN2; ATF3; SYTL2; PDE1B; TSGA10; RAPGEF3; AGO1; MED4

Interacting Protein

PPP3R2 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with PPP3R2 here. Most of them are supplied by our site. Hope this information will be useful for your research of PPP3R2.
TFCP2; AURKA; BUB1; CD14; CCND1; APC; MSH2; PTPN12; PTPRJ; SMAD4; PDGFRL; FBXW7; DLC1; MLH3

PPP3R2 Related Articles

Fleming, I; Busse, R; et al. Tyrosine phosphorylation and bradykinin-induced signaling in endothelial cells. AMERICAN JOURNAL OF CARDIOLOGY 80:A102-A109(1997).
Csortos, C; Zolnierowicz, S; et al. High complexity in the expression of the B' subunit of protein phosphatase 2A(0) - Evidence for the existence of at least seven novel isoforms. JOURNAL OF BIOLOGICAL CHEMISTRY 271:2578-2588(1996).