prdx4
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  • Official Full Name
  • peroxiredoxin 4
  • Background
  • The protein encoded by this gene is an antioxidant enzyme and belongs to the peroxiredoxin family. The protein is localized to the cytoplasm. Peroxidases of the peroxiredoxin family reduce hydrogen peroxide and alkyl hydroperoxides to water and alcohol with the use of reducing equivalents derived from thiol-containing donor molecules. This protein has been found to play a regulatory role in the activation of the transcription factor NF-kappaB.
  • Synonyms
  • PRDX4; peroxiredoxin 4; peroxiredoxin-4; AOE37 2; prx-IV; peroxiredoxin IV; antioxidant enzyme AOE372; thioredoxin peroxidase AO372; thioredoxin peroxidase (antioxidant enzyme); thioredoxin-dependent peroxide reductase A0372; PRX-4; AOE37-2
Cat.#:PRDX4-322HTag:His
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human PRDX4 Protein, His-tagged
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Cat.#:Prdx4-323MTag:His
Source (Host):E. coliSpecies:Mouse
Product nameRecombinant Mouse Prdx4 Protein, His-tagged
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Cat.#:PRDX4-1022HTag:N/A
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human PRDX4
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Cat.#:PRDX4-2048HTag:His
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human Peroxiredoxin 4, His-tagged
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Cat.#:PRDX4-30466THTag:His
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human PRDX4, His-tagged
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Cat.#:PRDX4-13325MTag:His
Source (Host):Mammalian CellsSpecies:Mouse
Product nameRecombinant Mouse PRDX4 Protein
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Cat.#:PRDX4-4660RTag:His
Source (Host):Mammalian CellsSpecies:Rat
Product nameRecombinant Rat PRDX4 Protein
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Cat.#:PRDX4-3592RTag:His
Source (Host):Mammalian CellsSpecies:Rhesus Macaque
Product nameRecombinant Rhesus monkey PRDX4 Protein, His-tagged
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Cat.#:PRDX4-5551ZTag:His
Source (Host):Mammalian CellsSpecies:Zebrafish
Product nameRecombinant Zebrafish PRDX4
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Cat.#:PRDX4-2880HCLTag:
Source (Host):Species:Human
Product nameRecombinant Human PRDX4 293 Cell Lysate
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Involved Pathway

PRDX4 involved in several pathways and played different roles in them. We selected most pathways PRDX4 participated on our site, such as Selenium Pathway, which may be useful for your reference. Also, other proteins which involved in the same pathway with PRDX4 were listed below. Creative Biomart supplied nearly all the proteins listed, you can search them on our site.
Pathway Name
Pathway Related Protein
Selenium Pathway
CRP; SELT; DIO2; SAA2; MSRB1; SAA4; SELK; SEP15; SAA2-SAA4; TXNRD2

Protein Function

PRDX4 has several biochemical functions, for example, protein binding, protein homodimerization activity, thioredoxin peroxidase activity. Some of the functions are cooperated with other proteins, some of the functions could acted by PRDX4 itself. We selected most functions PRDX4 had, and list some proteins which have the same functions with PRDX4. You can find most of the proteins on our site.
Function
Related Protein
Function protein binding
Related Protein MYBBP1A; MIER1; TRAF3IP1; MST1R; BATF2; PRR13; STAG3; TIMM21; BCKDK; PLG
Function protein homodimerization activity
Related Protein NUDT21; ATP2A1; FLT3LG; HNF1B; GZMA; MAP3K13; UPK1A; USH2A; Flt3l; FGFR1OP
Function thioredoxin peroxidase activity
Related Protein PRDX3; PRDX1; PRDX2; PRDX4

Interacting Protein

PRDX4 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with PRDX4 here. Most of them are supplied by our site. Hope this information will be useful for your research of PRDX4.
LBP; TBXA2R; NR4A1; PDIA6; P4HB; PDIA3; TXNDC5; CLIC1; MT-CO1; PLG