prkd1
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  • Official Full Name
  • protein kinase D1
  • Background
  • PRKD1 is a serine/threonine kinase that regulates a variety of cellular functions, including membrane receptor;signaling, transport at the Golgi, protection from oxidative stress at the mitochondria, gene transcription, and;regulation of cell shape, motility, and adhesion (summary by Eiseler et al., 2009 (PubMed 19329994)).
  • Synonyms
  • PRKD1; protein kinase D1; PRKCM, protein kinase C, mu; serine/threonine-protein kinase D1; PKC mu; PKCM; PKD; nPKC-D1; nPKC-mu; protein kinase D; protein kinase C, mu; protein kinase C mu type; PRKCM; PKC-MU
Cat.#:PRKD1-2711HTag:His|T7
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human PRKD1 protein, His & T7-tagged
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Cat.#:PRKD1-29764THTag:N/A
Source (Host):Species:Human
Product nameRecombinant Human PRKD1
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Cat.#:PRKD1-13372MTag:His
Source (Host):Mammalian CellsSpecies:Mouse
Product nameRecombinant Mouse PRKD1 Protein
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Cat.#:Prkd1-2712MTag:His|T7
Source (Host):E. coliSpecies:Mouse
Product nameRecombinant Mouse Prkd1 protein, His & T7-tagged
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Cat.#:PRKD1-2864CTag:His
Source (Host):Mammalian CellsSpecies:Chicken
Product nameRecombinant Chicken PRKD1
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Cat.#:PRKD1-406HTag:GST
Source (Host):Sf 9 Insect cellsSpecies:Human
Product nameRecombinant Human Protein Kinase D1, GST-tagged, Active
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Cat.#:PRKD1-2851HCLTag:N/A
Source (Host):Species:Human
Product nameRecombinant Human PRKD1 293 Cell Lysate
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Involved Pathway

PRKD1 involved in several pathways and played different roles in them. We selected most pathways PRKD1 participated on our site, such as Rap signaling pathway, Aldosterone synthesis and secretion, which may be useful for your reference. Also, other proteins which involved in the same pathway with PRKD1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
Pathway Name
Pathway Related Protein
Rap signaling pathway
GNAS; PIK3R2; FGFR3; PRKD1; PLCB1; IGF1R; RAPGEF1; PIK3CA; MAPK13; F2R
Aldosterone synthesis and secretion
AKR1C1; CAMK2D; CAMK4; ADCY8; CALM3; ATF4; CAMK2B; DDX1; ATF1; LIPE

Protein Function

PRKD1 has several biochemical functions, for example, ATP binding, identical protein binding, metal ion binding. Some of the functions are cooperated with other proteins, some of the functions could acted by PRKD1 itself. We selected most functions PRKD1 had, and list some proteins which have the same functions with PRKD1. You can find most of the proteins on our site.
Function
Related Protein
Function ATP binding
Related Protein C10orf2; GSK3AB; BMPR1A; DCAKD; EK1; PFKFB4L; MAGI1; BLK; ALPK1; DGKAA
Function identical protein binding
Related Protein AMOTL2; SHMT2; DESI1; PFKFB1; KDM6A; SH3BP4; PACSIN2; CHMP4B; MUL1A; ADORA2A
Function metal ion binding
Related Protein ZBED3; ZNF554; HIVEP2A; ARSH; CYP4F14; NUFIP1; PLA2G4F; EGR4; CRYABA; IMPDH1
Function protein binding
Related Protein EXOC4; SPSB4; PCGF3; ADORA2A; BAI3; RPL14; MKRN2; P4HB; RPL5; SLC19A2
Function protein kinase C activity
Related Protein PRKCBA; PKN3; PRKCD; PRKD3; PRKCI; PRKD2; PRKCG; PRKCQ; PRKCE; PRKCHA
Function protein serine/threonine kinase activity
Related Protein RIPK1; VRK2; PINK1; STK40; MELK; PRKDC; IRAK1; SLC14A2; ULK2; SBK3

Interacting Protein

PRKD1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with PRKD1 here. Most of them are supplied by our site. Hope this information will be useful for your research of PRKD1.
C1QBP; N/A; MAPK13; MT2A

PRKD1 Related Articles

Du, X; Li, YM; et al. Effect of a heat shock protein 90-specific inhibitor on the proliferation and apoptosis induced by VEGF-C in cervical cancer cells. EXPERIMENTAL AND THERAPEUTIC MEDICINE 8:1559-1564(2014).
Sidhu, PS; Teske, K; et al. Anticancer activity of VDR-coregulator inhibitor PS121912. CANCER CHEMOTHERAPY AND PHARMACOLOGY 74:787-798(2014).