prmt2
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  • Official Full Name
  • protein arginine methyltransferase 2
  • Background
  • Protein arginine N-methyltransferase 2 is an enzyme that in humans is encoded by the PRMT2 gene.
  • Synonyms
  • PRMT2; protein arginine methyltransferase 2; HMT1 (hnRNP methyltransferase, S. cerevisiae) like 1 , HMT1 hnRNP methyltransferase like 1 (S. cerevisiae) , HRMT1L1; protein arginine N-methyltransferase 2; MGC111373; PRMT2 beta; PRMT2 alpha; PRMT2 gamma; HM
Cat.#:PRMT2-125HTag:GST
Source (Host):Wheat GermSpecies:Human
Product nameRecombinant Human PRMT2 protein, GST-tagged
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Cat.#:PRMT2-12HTag:GST
Source (Host):Insect cellsSpecies:Human
Product nameRecombinant Human PRMT2 protein, GST-tagged
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Cat.#:PRMT2-31115THTag:His
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human PRMT2, His-tagged
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Cat.#:PRMT2-3613RTag:His
Source (Host):Mammalian CellsSpecies:Rhesus Macaque
Product nameRecombinant Rhesus monkey PRMT2 Protein, His-tagged
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Cat.#:PRMT2-5034ZTag:His
Source (Host):Mammalian CellsSpecies:Zebrafish
Product nameRecombinant Zebrafish PRMT2
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Cat.#:PRMT2-2839HCLTag:
Source (Host):Species:Human
Product nameRecombinant Human PRMT2 293 Cell Lysate
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Involved Pathway

PRMT2 involved in several pathways and played different roles in them. We selected most pathways PRMT2 participated on our site, such as RB in Cancer, mRNA processing, which may be useful for your reference. Also, other proteins which involved in the same pathway with PRMT2 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
Pathway Name
Pathway Related Protein
RB in Cancer
PRMT2; DCK; HLTF; TOP2A; RBP1; HMGB2; SMARCA2; ANLN; RABIF; FAF1
mRNA processing
LOC100862398; FAM120B; HNRNPAB; BICC1; EIF4E3; ZFP740; CELF1; NONO; SFPQ; RBM39A

Protein Function

PRMT2 has several biochemical functions, for example, androgen receptor binding, estrogen receptor binding, histone methyltransferase activity. Some of the functions are cooperated with other proteins, some of the functions could acted by PRMT2 itself. We selected most functions PRMT2 had, and list some proteins which have the same functions with PRMT2. You can find most of the proteins on our site.
Function
Related Protein
Function androgen receptor binding
Related Protein NCOA4; Ar; RNF4; SMARCA4; DAXX; KDM4C; KDM3A; PIAS2; TRIM68; PRMT2
Function estrogen receptor binding
Related Protein CCDC62; PRMT2; HSD17B10; CTNNB1; LEF1; CNOT1; PPARGC1A; FOXL2; XBP1; PPID
Function histone methyltransferase activity
Related Protein SUV39H1; PRMT2; PRDM13; EED; PRMT6; EZH2; SUZ12; CARM1; PRMT1
Function histone-arginine N-methyltransferase activity
Related Protein PRMT8; PRMT7; PRMT6; PRMT5; CARM1; PRMT2; PRMT3
Function peroxisome proliferator activated receptor binding
Related Protein HMGA1-RS1; NR0B2; MED1; NFATC4; CREBBP; EP300; HMGA1; IKBKG; ASXL1; ASXL2
Function progesterone receptor binding
Related Protein PRMT2; NCOA1
Function protein binding
Related Protein PMAIP1; RPS6KC1; SYNGR1; ATRX; MATN2; GOLGA8G; NPM2; GP6; TMEM173; NOP10
Function protein homodimerization activity
Related Protein DMRTA1; TIGIT; RPE; SLC4A1; ZHX3; RCHY1; NKX2; P2RX4; CBS; VPS25
Function protein-arginine N-methyltransferase activity
Related Protein METTL23; FAM86; RNMTL1B; PRDM13; RNMTL1A; PRMT2; METTL21D; PRMT8B; PRMT5; DIMT1
Function protein-arginine omega-N asymmetric methyltransferase activity
Related Protein PRMT3; PRMT2; PRMT1; PRMT8B; CARM1; PRMT6; PRMT8; PRMT7
Function retinoic acid receptor binding
Related Protein ACTN4; PRMT2; PRAMEF6; AASS; PRAMEF1; CTBP2; NSD1; SNW1; PRAMEF2; HMGA1-RS1
Function signal transducer activity
Related Protein ADRB3A; TAAR10A; GNA13; VMN1R41; OLFCS2; STAT3; TAAR13B; GNG8; TACR3L; OMP
Function thyroid hormone receptor binding
Related Protein NCOR1; NUP62; GTF2B; THRAP3; FUS; NSD1; MED24; MED30; TRIP12; TAF11
Function transcription coactivator activity
Related Protein GMEB1; STIL; TBPL1; ESR2; SP4; NR1H3; TFDP1B; BRCA1; TDRD3; HAND1

Interacting Protein

PRMT2 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with PRMT2 here. Most of them are supplied by our site. Hope this information will be useful for your research of PRMT2.
ESR1; RB1; AKR1B1; PGR; NPM1; THRB; RXRA; HNRNPK