|Official Full Name||peptidyl-tRNA hydrolase 2|
|Background||The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis. Promotes caspase-independent apoptosis by regulating the function of two transcriptional regulators, AES and TLE1.|
|Synonyms||PTRH2; peptidyl-tRNA hydrolase 2; peptidyl-tRNA hydrolase 2, mitochondrial; Bcl 2 inhibitor of transcription; BIT1; CGI 147; PTH2; PTH 2; bcl-2 inhibitor of transcription 1; CGI-147; FLJ32471|
|Species||Cat.#||Product name||Source (Host)||Tag||Protein Length||Price|
PTRH2 involved in several pathways and played different roles in them. We selected most pathways PTRH2 participated on our site, such as Apoptosis Modulation and Signaling, which may be useful for your reference. Also, other proteins which involved in the same pathway with PTRH2 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
|Pathway Name||Pathway Related Protein|
|Apoptosis Modulation and Signaling||SEPT4; BIK; DFFA; BAG3; DIABLO; CAPNS1; CRADD; BCL2L11; CASP2; BCL2L10|
PTRH2 has several biochemical functions, for example, aminoacyl-tRNA hydrolase activity, protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by PTRH2 itself. We selected most functions PTRH2 had, and list some proteins which have the same functions with PTRH2. You can find most of the proteins on our site.
|aminoacyl-tRNA hydrolase activity||PTRH2; C12orf65; PTRHD1; ICT1; PTRH1|
|protein binding||CCDC109A; PRICKLE1; DDX58; LYAR; MB21D2; CAPN1; PRKAR1A; RCOR2; PYDC1; CD1B|
PTRH2 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with PTRH2 here. Most of them are supplied by our site. Hope this information will be useful for your research of PTRH2.
AES; PTK2; IKBKE; ssrna_ag; CLTC; P