pus7
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  • Official Full Name
  • pseudouridylate synthase 7 homolog
  • Synonyms
  • PUS7; pseudouridylate synthase 7 homolog (S. cerevisiae); pseudouridylate synthase 7 homolog; FLJ20485; KIAA1897; MGC17720
Cat.#:PUS7-2075HTag:GST
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human PUS7, GST-tagged
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Cat.#:PUS7-4373CTag:His
Source (Host):Mammalian CellsSpecies:Chicken
Product nameRecombinant Chicken PUS7
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Cat.#:PUS7-6575ZTag:His
Source (Host):Mammalian CellsSpecies:Zebrafish
Product nameRecombinant Zebrafish PUS7
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Cat.#:PUS7-2660HCLTag:
Source (Host):Species:Human
Product nameRecombinant Human PUS7 293 Cell Lysate
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Involved Pathway

PUS7 involved in several pathways and played different roles in them. We selected most pathways PUS7 participated on our site, such as Gene Expression, tRNA modification in the nucleus and cytosol, tRNA processing, which may be useful for your reference. Also, other proteins which involved in the same pathway with PUS7 were listed below. Creative Biomart supplied nearly all the proteins listed, you can search them on our site.
Pathway Name
Pathway Related Protein
Gene Expression
TRMT6; PPARAA; NFIB; SNAPC1; ZNF571; ZNF446; SPCS3; SMARCA5; HNRNPA0B; SLBP
tRNA modification in the nucleus and cytosol
TPRKB; TRMT11; TRMT1; TRMT61A; PUS7; KIAA1456; TRDMT1; LCMT2; PUS1; TYW1
tRNA processing
POP4; TPRKB; LBH; C2orf49; QTRT1; CDKAL1; C22orf28; PUS7; CCDC76; LCMT2

Protein Function

PUS7 has several biochemical functions, for example, enzyme binding, poly(A) RNA binding, pseudouridine synthase activity. Some of the functions are cooperated with other proteins, some of the functions could acted by PUS7 itself. We selected most functions PUS7 had, and list some proteins which have the same functions with PUS7. You can find most of the proteins on our site.
Function
Related Protein
Function enzyme binding
Related Protein SUDS3; BLZF1; TSPAN5; HYAL2; PARP4; TULP3; CAV1; SNRPD3; TP53; HDAC3
Function poly(A) RNA binding
Related Protein RBM12B1; WDR3; ARCN1; CHCHD1; P4HB; MYEF2; PES1; TMSB4X; NUDT16L1; APEH
Function pseudouridine synthase activity
Related Protein RPUSD1; TRUB2; PUSL1; RPUSD3; PUS7; RPUSD2; PUS1; PUS7L; RPUSD4; PUS3

Interacting Protein

PUS7 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with PUS7 here. Most of them are supplied by our site. Hope this information will be useful for your research of PUS7.
MCC; ssrna_ug; CXXC4

PUS7 Related Articles

Schwartz, S; Bernstein, DA; et al. Transcriptome-wide Mapping Reveals Widespread Dynamic-Regulated Pseudouridylation of ncRNA and mRNA. CELL 159:148-162(2014).
Wu, GW; Xiao, M; et al. U2 snRNA is inducibly pseudouridylated at novel sites by Pus7p and snR81 RNP. EMBO JOURNAL 30:79-89(2011).