Recombinant Full Length Human PUS7 Protein, His tagged

• Cat.No.: PUS7-20HFL
• Product Overview: PUS7 Protein, Human (sf9, His) is the recombinant human-derived PUS7, expressed by sf9 insect cells, with His tag.

Specification

• Species: Human
• Source: Insect Cells
• Tag: His
• Protein Length: 2-661 aa
• Description: Enables enzyme binding activity and tRNA pseudouridine(13) synthase activity. Involved in several processes, including pseudouridine synthesis; regulation of hematopoietic stem cell differentiation; and regulation of mesoderm development. Is active in nucleus. Implicated in intellectual developmental disorder with abnormal behavior, microcephaly, and short stature.
• Form: Liquid. Supplied as a 0.22 μm filtered solution of 50 mM HEPES, pH 7.5, 200 mM NaCl, 20% glycerol, 1 mM DTT.
• Molecular Mass: Approximately 78.1 kDa
• Endotoxin: <1 EU/μg determined by LAL method.
• Purity: Greater than 90% as determined by reducing SDS-PAGE
• Storage: Stored at -80 centigrade for 1 year from date of receipt. It is stable at -20 centigrade for 3 months after opening. It is recommended to freeze aliquots at -80 centigrade for extended storage. Avoid repeated freeze-thaw cycles.
• Concentration: 1.87 mg/mL
• Shipping: Shipping with dry ice.
• Reconstitution: Please use rapid thawing with running water to thaw the protein

Gene Information

• Gene Name: PUS7 pseudouridine synthase 7 [ Homo sapiens (human) ]
• Official Symbol: PUS7
• Synonyms: PUS7; pseudouridine synthase 7; IDDABS; pseudouridylate synthase 7 homolog; pseudouridylate synthase 7 (putative); EC 4.2.1.70
• Gene ID: 54517
• mRNA Refseq: NM_019042
• Protein Refseq: NP_061915
• MIM: 616261
• UniProt ID: Q96PZ0