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Official Full Name quinoid dihydropteridine reductase
Background This gene encodes the enzyme dihydropteridine reductase, which catalyzes the NADH-mediated reduction of quinonoid dihydrobiopterin.This enzyme is an essential component of the pterin-dependent aromatic amino acid hydroxylating systems. Mutations in this gene resulting in QDPR deficiency include aberrant splicing, amino acid substitutions, insertions, or premature terminations.Dihydropteridine reductase deficiency presents as atypical phenylketonuria due to insufficient production of biopterin, a cofactor for phenylalanine hydroxylase.
Synonyms QDPR; quinoid dihydropteridine reductase; dihydropteridine reductase; 6; 7 dihydropteridine reductase; DHPR; PKU2; SDR33C1; short chain dehydrogenase/reductase family 33C; member 1; DHPR_HUMAN; HDHPR; HPR; OTTHUMP00000158671; OTTHUMP00000217799; OTTHUMP00000217800; OTTHUMP00000217802; OTTHUMP00000217914; OTTHUMP00000217915; 6,7-dihydropteridine reductase; short chain dehydrogenase/reductase family 33C, member 1
    • Species :
    • Chicken
    • Human
    • Mouse
    • Rat
    • Source :
    • E.coli
    • HEK293
    • HEK293T
    • Mammalian Cell
    • Tag :
    • His
    • MYC/DDK
    • Myc
    • DDK
    • N/A
    Species Cat.# Product name Source (Host) Tag Protein Length Price
    Human QDPR-3987H Recombinant Human QDPR Protein, Myc/DDK-tagged, C13 and N15-labeled HEK293T Myc/DDK
    Mouse Qdpr-471M Recombinant Mouse Qdpr Protein, MYC/DDK-tagged HEK293T MYC/DDK
    Human QDPR-160H Recombinant Human QDPR Protein, MYC/DDK-tagged HEK293 Myc/DDK
    Human QDPR-2090H Recombinant Human QDPR, His-tagged E.coli His
    Human QDPR-30230TH Recombinant Human QDPR, His-tagged E.coli His
    Human QDPR-3613H Recombinant Human QDPR, His-tagged E.coli His
    Human QDPR-520HCL Recombinant Human QDPR lysate HEK293 N/A
    Human QDPR-679H Recombinant Human QDPR Protein, His-tagged HEK293 His
    Mouse QDPR-13760M Recombinant Mouse QDPR Protein Mammalian Cell His
    Rat QDPR-4863R Recombinant Rat QDPR Protein Mammalian Cell His
    Chicken QDPR-1703C Recombinant Chicken QDPR Mammalian Cell His

    QDPR involved in several pathways and played different roles in them. We selected most pathways QDPR participated on our site, such as Folate biosynthesis, Metabolic pathways, which may be useful for your reference. Also, other proteins which involved in the same pathway with QDPR were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein
    Folate biosynthesis QDPR; DHFR; SPRA; PTS; QDPRB1; QDPRB2; GGH; ALPI.2; MOCS2; GCH1
    Metabolic pathways SPHK1; ATP5C1; CRYL1; HADH; ACSM3; SAT1A.1; ACSM5; AOX1; ALPP; REV3L

    QDPR has several biochemical functions, for example, 6,7-dihydropteridine reductase activity, NADH binding, NADPH binding. Some of the functions are cooperated with other proteins, some of the functions could acted by QDPR itself. We selected most functions QDPR had, and list some proteins which have the same functions with QDPR. You can find most of the proteins on our site.

    Function Related Protein
    6,7-dihydropteridine reductase activity QDPR
    NADH binding CTBP2; CTBP2A; CTBP1; QDPR
    electron carrier activity ACAD11; XDH; ACOX1; AOX1; GLRX3; COX11; ADH5; NOX4; ACADSB; FDX1
    protein homodimerization activity TYR; UGT1A7; AMICA1; ABCD2; GSTM1; TSG101; CHMP4A; GIPC1; C6orf108; PTPRE

    QDPR has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with QDPR here. Most of them are supplied by our site. Hope this information will be useful for your research of QDPR.

    KRAS; CASP8; sch51344; APOA1; IQCB1

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