|Official Full Name||REST corepressor 1|
|Background||This gene encodes a protein that is well-conserved, downregulated at birth, and with a specific role in determining neural cell differentiation. The encoded protein binds to the C-terminal domain of REST (repressor element-1 silencing transcription factor). [provided by RefSeq, Aug 2011]|
|Synonyms||RCOR1; REST corepressor 1; RCOR; COREST;|
|Species||Cat.#||Product name||Source (Host)||Tag||Protein Length||Price|
RCOR1 involved in several pathways and played different roles in them. We selected most pathways RCOR1 participated on our site, such as Huntingtons disease, which may be useful for your reference. Also, other proteins which involved in the same pathway with RCOR1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
|Pathway Name||Pathway Related Protein|
|Huntingtons disease||SDHC; COX4I1; PLCB1; TFAM; CASP8; COX6B1; DNALC1; SP1; GRM5; NDUFA4L2|
RCOR1 has several biochemical functions, for example, DNA binding, enzyme binding, protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by RCOR1 itself. We selected most functions RCOR1 had, and list some proteins which have the same functions with RCOR1. You can find most of the proteins on our site.
|DNA binding||SALL3; SIM1; KAT6A; POLR3B; SMAD3B; NFE2L2B; ZFP511; HIST1H2AK; ZNF222; PALB2|
|enzyme binding||KIAA1967; POR; PCCA; NLRP1; NFKBIA; RFC5; HYAL2; CYP2A6; SCARB2; CYP3A4|
|protein binding||ARIH2; SSTR3; MAGI2; HIST1H2AL; ECT2; NOC2L; JUB; TEKT5; CHD4; TGFBR1|
|transcription regulatory region DNA binding||HNF4A; ATMIN; EGR2; ASH2L; TP53; ETV5; H2AFY; SALL1A; TCF7L1A; SP1|
|transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding||TFAP2A; HSF1; ZFPM2; NFIL3-6; BCL11A; NFIL3-4; IFI203; PYDC3; SNAI1; TBX15|
RCOR1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with RCOR1 here. Most of them are supplied by our site. Hope this information will be useful for your research of RCOR1.
Nr4a2; Gfi1b; inos_mouse_gene; tnfa_mouse_gene; Hdac1; Hdac2; Nanog