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Recombinant Human RCOR1 protein, GST-tagged

Cat.No. : RCOR1-73H
Product Overview : Recombinant Human RCOR1(1 a.a. - 482 a.a.) fused with GST tag at N-terminal was expressed in Wheat Germ.
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  • Gene Information
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Description : This gene encodes a protein that is well-conserved, downregulated at birth, and with a specific role in determining neural cell differentiation. The encoded protein binds to the C-terminal domain of REST (repressor element-1 silencing transcription factor).
Source : Wheat Germ
Species : Human
Tag : GST
Form : 50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.
Molecular Mass : 79.97 kDa
AA Sequence : MVEKGPEVSGKRRGRNNAAASASAA AASAAASAACASPAATAASGAAASS ASAAAASAAAAPNNGQNKSLAAAAP NGNSSSNSWEEGSSGSSSDEEHGGG GMRVGPQYQAVVPDFDPAKLARRSQ ERDNLGMLVWSPNQNLSEAKLDEYI AIAKEKHGYNMEQALGMLFWHKHNI EKSLADLPNFTPFPDEWTVEDKVLF EQAFSFHGKTFHRIQQMLPDKSIAS LVKFYYSWKKTRTKTSVMDRHARKQ KREREESEDELEEANGNNPIDIEVD QNKESKKEVPPTETVPQVKKEKHST QAKNRAKRKPPKGMFLSQEDVEAVS ANATAATTVLRQLDMELVSVKRQIQ NIKQTNSALKEKLDGGIEPYRLPEV IQKCNARWTTEEQLLAVQAIRKYGR DFQAISDVIGNKSVVQVKNFFVNYR RRFNIDEVLQEWEAEHGKEETNGPS NQKPVKSPDNSIKMPEEEDEAPVLD VRYASAS
Applications : Enzyme-linked Immunoabsorbent Assay; Western Blot (Recombinant protein); Antibody Production; Protein Array
Notes : Best use within three months from the date of receipt of this protein.
Storage : Store at -80 centigrade. Aliquot to avoid repeated freezing and thawing.
Gene Name : RCOR1 REST corepressor 1 [ Homo sapiens ]
Official Symbol : RCOR1
Synonyms : RCOR1; REST corepressor 1; RCOR, REST corepressor; COREST; KIAA0071; RCOR;
Gene ID : 23186
mRNA Refseq : NM_015156
Protein Refseq : NP_055971
MIM : 607675
UniProt ID : Q9UKL0
Chromosome Location : 14q32.33
Pathway : Factors involved in megakaryocyte development and platelet production, organism-specific biosystem; Hemostasis, organism-specific biosystem; Huntingtons disease, organism-specific biosystem; Huntingtons disease, conserved biosystem;
Function : DNA binding; RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in negative regulation of transcription; protein binding; transcription regulatory region DNA binding;

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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Q&As (5)

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What are the potential limitations of using RCOR1 protein as a clinical biomarker? 01/10/2023

Potential limitations include the need for standardized assays, variability in protein expression levels, and the influence of confounding factors on its levels.

Are there any genetic variations in the RCOR1 gene that impact its clinical relevance? 08/25/2022

Yes, genetic variations in the RCOR1 gene have been associated with susceptibility to certain neurodegenerative and neurodevelopmental disorders.

How is RCOR1 protein linked to neurodevelopmental disorders? 02/21/2019

Dysregulation of RCOR1 protein has been associated with neurodevelopmental disorders such as autism spectrum disorders and intellectual disabilities.

How does RCOR1 protein interact with other proteins in the context of clinical applications? 11/16/2016

RCOR1 protein interacts with various transcription factors and epigenetic regulators, and understanding these interactions is crucial for its clinical relevance.

Can RCOR1 protein be used for personalized medicine in neurology? 09/01/2016

There is emerging research into using RCOR1 protein profiles for personalized treatment strategies in neurology, especially for patients with neurodegenerative and neurodevelopmental conditions.

Customer Reviews (3)

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Reviews
05/22/2020

    Such dedicated support makes me feel confident in my choice of using the RCOR1 protein for my experiments.

    01/16/2019

      I am highly impressed with the RCOR1 protein as it is of exceptionally high quality, and I am confident that it will perfectly meet the specific requirements of my experiments.

      06/21/2016

        With their extensive knowledge and expertise, I am assured that any challenges or issues I may encounter during my research will be efficiently resolved.

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