rgn
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  • Official Full Name
  • regucalcin (senescence marker protein-30)
  • Background
  • The protein encoded by this gene is a highly conserved, calcium-binding protein, that is preferentially expressed in the liver and kidney. It may have an important role in calcium homeostasis. Studies in rat indicate that this protein may also play a role in aging, as it shows age-associated down-regulation. This gene is part of a gene cluster on chromosome Xp11.3-Xp11.23. Alternative splicing results in two transcript variants having different 5 UTRs, but encoding the same protein.
  • Synonyms
  • RGN; regucalcin (senescence marker protein-30); regucalcin; RC; senescence marker protein 30; SMP30; Gluconolactonase; GNL; RGN_HUMAN; SMP 30; SMP-30; OTTHUMP00000023195; OTTHUMP00000023196; senescence marker protein-30
Cat.#:RGN-1505RTag:His
Source (Host):YeastSpecies:Rat
Product nameRecombinant Rat RGN Protein (1-299 aa), His-tagged
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Cat.#:RGN-30488THTag:His
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human RGN, His-tagged
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Cat.#:RGN-3642HTag:His
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human RGN, His-tagged
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Cat.#:RGN-14128MTag:His
Source (Host):Mammalian CellsSpecies:Mouse
Product nameRecombinant Mouse RGN Protein
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Cat.#:Rgn-8051MTag:His/T7
Source (Host):E. coliSpecies:Mouse
Product nameRecombinant Mouse Rgn protein, His & T7-tagged
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Cat.#:RGN-5012RTag:His
Source (Host):Mammalian CellsSpecies:Rat
Product nameRecombinant Rat RGN Protein
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Cat.#:Rgn-8052RTag:His/T7
Source (Host):E. coliSpecies:Rat
Product nameRecombinant Rat Rgn protein, His & T7-tagged
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Cat.#:RGN-3870RTag:His
Source (Host):Mammalian CellsSpecies:Rhesus Macaque
Product nameRecombinant Rhesus monkey RGN Protein, His-tagged
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Cat.#:RGN-6294CTag:His
Source (Host):Mammalian CellsSpecies:Chicken
Product nameRecombinant Chicken RGN
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Cat.#:RGN-11761ZTag:His
Source (Host):Mammalian CellsSpecies:Zebrafish
Product nameRecombinant Zebrafish RGN
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Cat.#:RGN-2388HCLTag:
Source (Host):Species:Human
Product nameRecombinant Human RGN 293 Cell Lysate
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Involved Pathway

RGN involved in several pathways and played different roles in them. We selected most pathways RGN participated on our site, such as Pentose phosphate pathway, Ascorbate and aldarate metabolism, Metabolic pathways, which may be useful for your reference. Also, other proteins which involved in the same pathway with RGN were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
Pathway Name
Pathway Related Protein
Pentose phosphate pathway
PGLS; PGM2; PFKL; RBKS; ALDOCA; ALDOCB; TKTL2; TKTL1; ALDOAB; FBP1B
Ascorbate and aldarate metabolism
ALDH3A2; UGT2A3; MIOX; GULO; UGT2B15; UGT1A4; UGDH; UGT1A3; ALDH2; UGT1A6A
Metabolic pathways
G6PD; ATIC; ALDH9A1A.1; NDUFA11; LIPCA; PLB1; GPAT2; GLB1; TYRP1B; ALG6
Carbon metabolism
ACSS2; PGD; HKDC1; SUCLA2; ENO1B; FBP2; SHMT2; TKT; PGK2; PGAM1B
Degradation of aromatic compounds
AKR1A1B; AKR1A1; ADH5; AKR1A1A; RGN

Protein Function

RGN has several biochemical functions, for example, calcium ion binding, enzyme regulator activity, gluconolactonase activity. Some of the functions are cooperated with other proteins, some of the functions could acted by RGN itself. We selected most functions RGN had, and list some proteins which have the same functions with RGN. You can find most of the proteins on our site.
Function
Related Protein
Function calcium ion binding
Related Protein MMP13; CD248; MICU2; PADI1; MMP20; EML1; PCDHGC3; PCDHB13; PCDH2G9; ABP1
Function enzyme regulator activity
Related Protein RGN; PPP1R7; PSMD1; PSMD3; GCLM; APOC3; PSMD2; DPM2; SEPT2; RAB3GAP2
Function gluconolactonase activity
Related Protein RGN
Function zinc ion binding
Related Protein RFPL4B; CHORDC1; ALPP; TRIM7; SIRT6; SNCA; RNFT1; SNAI1A; TRIM55A; ATXN7L3