RGN Protein, regucalcin (senescence marker protein-30)


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Official Full Name regucalcin (senescence marker protein-30)
Background The protein encoded by this gene is a highly conserved, calcium-binding protein, that is preferentially expressed in the liver and kidney. It may have an important role in calcium homeostasis. Studies in rat indicate that this protein may also play a role in aging, as it shows age-associated down-regulation. This gene is part of a gene cluster on chromosome Xp11.3-Xp11.23. Alternative splicing results in two transcript variants having different 5 UTRs, but encoding the same protein.
Synonyms RGN; regucalcin (senescence marker protein-30); regucalcin; RC; senescence marker protein 30; SMP30; Gluconolactonase; GNL; RGN_HUMAN; SMP 30; SMP-30; OTTHUMP00000023195; OTTHUMP00000023196; senescence marker protein-30
    • Species :
    • Chicken
    • Human
    • Mouse
    • Rat
    • Rhesus Macaque
    • Zebrafish
    • Source :
    • E.coli
    • HEK293
    • Human
    • Mammalian Cell
    • Yeast
    • Tag :
    • His
    • T7
    • N/A
    Species Cat.# Product name Source (Host) Tag Protein Length Price
    Rat RGN-1505R Recombinant Rat RGN Protein (1-299 aa), His-tagged Yeast His
    Human RGN-2388HCL Recombinant Human RGN 293 Cell Lysate HEK293 N/A
    Human RGN-30488TH Recombinant Human RGN, His-tagged E.coli His
    Human RGN-3642H Recombinant Human RGN, His-tagged Human His
    Mouse RGN-14128M Recombinant Mouse RGN Protein Mammalian Cell His
    Mouse Rgn-8051M Recombinant Mouse Rgn protein, His & T7-tagged E.coli His/T7
    Rat RGN-5012R Recombinant Rat RGN Protein Mammalian Cell His
    Rat Rgn-8052R Recombinant Rat Rgn protein, His & T7-tagged E.coli His/T7
    Rhesus Macaque RGN-3870R Recombinant Rhesus monkey RGN Protein, His-tagged Mammalian Cell His
    Chicken RGN-6294C Recombinant Chicken RGN Mammalian Cell His
    Zebrafish RGN-11761Z Recombinant Zebrafish RGN Mammalian Cell His

    RGN involved in several pathways and played different roles in them. We selected most pathways RGN participated on our site, such as Pentose phosphate pathway, Ascorbate and aldarate metabolism, Metabolic pathways, which may be useful for your reference. Also, other proteins which involved in the same pathway with RGN were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein
    Pentose phosphate pathway GPIB; H6PD; ALDOC; PFKL; ALDOA; ALDOCB; PRPS1B; PFKMA; RPIA; TKTL2
    Ascorbate and aldarate metabolism ALDH9A1B; UGT1AB; ALDH9A1A.1; UGT2A1; UGT1A7C; ALDH7A1; UGT1A2; UGT1A4; GULO; UGDH
    Metabolic pathways NAPRT1; GBA3; NT5C1AA; CYP3A41A; DHRS4L2; ACSM2B; ENPP3; CSGALNACT2; POLE2; MAT1A
    Carbon metabolism IDH3B; HAO1; ADPGK; PGK2; GLUD1B; PGAM2; HK2; OGDHA; MCEE; OGDH
    Degradation of aromatic compounds ADH5; AKR1A1B; RGN; AKR1A1A; AKR1A1

    RGN has several biochemical functions, for example, calcium ion binding, enzyme regulator activity, gluconolactonase activity. Some of the functions are cooperated with other proteins, some of the functions could acted by RGN itself. We selected most functions RGN had, and list some proteins which have the same functions with RGN. You can find most of the proteins on our site.

    Function Related Protein
    calcium ion binding DSG4; SLIT1B; LRP4; FSTL4; EGFL7; RCV1; RPH3AL; UMOD; SRR; CABYR
    enzyme regulator activity APOC3; RGN; MTMR9; PSMD3; ATP6V1H; PPP1R7; EIF2B1; SEPT2; PSMD1; DCP1B
    gluconolactonase activity RGN
    zinc ion binding TRAF2; ING5B; LIMK1A; TRIM43A; ANPEP; NR3C1; LMO4B; MMP17; NEURL1B; MATR3

    RGN has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with RGN here. Most of them are supplied by our site. Hope this information will be useful for your research of RGN.

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