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RGS3

  • Official Full Name

    regulator of G-protein signaling 3

  • Overview

    This gene encodes a member of the regulator of G-protein signaling (RGS) family. This protein is a GTP-ase activating protein which inhibits G-protein mediated signal transduction. The protein is largely cytosolic, but G-protein activation leads to translocation of this protein to the plasma membrane. A nuclear form of this protein has also been described, but its sequence has not been identified. Multiple alternatively spliced transcript variants have been described for this gene but the full-length nature of some transcripts is not yet known.
  • Synonyms

    RGS3; regulator of G-protein signaling 3; regulator of G protein signalling 3; C2PA; FLJ20370; PDZ RGS3; regulator of G-protein signalling 3; RGP3; PDZ-RGS3; FLJ31516; FLJ90496;

  • Recombinant Proteins
  • Cell & Tissue Lysates
  • Protein Pre-coupled Magnetic Beads
  • Chicken
  • Human
  • Mouse
  • Rat
  • E.coli
  • HEK293
  • HEK293T
  • In Vitro Cell Free System
  • Mammalian Cell
  • Wheat Germ
  • C
  • Myc
  • DDK
  • GST
  • His
  • His (Fc)
  • Avi
  • His|T7
  • N/A
Species Cat.# Product name Source (Host) Tag Protein Length Price
Human RGS3-29967TH Recombinant Human RGS3 Wheat Germ N/A 193 amino acids
Human RGS3-2280H Recombinant Human RGS3, GST-tagged E.coli GST C-term-241aa
Human RGS3-392H Recombinant Human RGS3 Protein, His-tagged E.coli His
Human RGS3-2373HCL Recombinant Human RGS3 293 Cell Lysate HEK293 N/A
Human RGS3-2374HCL Recombinant Human RGS3 293 Cell Lysate HEK293 N/A
Human RGS3-2375HCL Recombinant Human RGS3 293 Cell Lysate HEK293 N/A
Human RGS3-2376HCL Recombinant Human RGS3 293 Cell Lysate HEK293 N/A
Human RGS3-339H Recombinant Human RGS3 Protein, MYC/DDK-tagged, C13 and N15-labeled HEK293 C-Myc/DDK
Human RGS3-3107H Recombinant Human RGS3 Protein, Myc/DDK-tagged, C13 and N15-labeled HEK293T Myc/DDK
Human RGS3-3795H Recombinant Human RGS3 Protein, Myc/DDK-tagged, C13 and N15-labeled HEK293T Myc/DDK
Human RGS3-452HF Recombinant Full Length Human RGS3 Protein In Vitro Cell Free System 193 amino acids
Mouse RGS3-14144M Recombinant Mouse RGS3 Protein Mammalian Cell His
Mouse Rgs3-8186M Recombinant Mouse Rgs3 protein, His & T7-tagged E.coli His/T7 Met1~Thr261 (Accession # Q9DC04)
Mouse RGS3-7567M-B Recombinant Mouse RGS3 Protein Pre-coupled Magnetic Beads HEK293
Mouse Rgs3-5498M Recombinant Mouse Rgs3 Protein, Myc/DDK-tagged HEK293T Myc/DDK
Mouse RGS3-7567M Recombinant Mouse RGS3 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Rat RGS3-5019R Recombinant Rat RGS3 Protein Mammalian Cell His
Rat RGS3-4678R-B Recombinant Rat RGS3 Protein Pre-coupled Magnetic Beads HEK293
Rat RGS3-4678R Recombinant Rat RGS3 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Chicken RGS3-6029C Recombinant Chicken RGS3 Mammalian Cell His
  • Involved Pathway
  • Protein Function
  • Interacting Protein

RGS3 involved in several pathways and played different roles in them. We selected most pathways RGS3 participated on our site, such as Axon guidance, which may be useful for your reference. Also, other proteins which involved in the same pathway with RGS3 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name Pathway Related Protein
Axon guidanceFRS2;SEMA4D;DCC;NTN1B;NRG2A;AP2M1;SEMA5B;KBTBD7;RHOD

RGS3 has several biochemical functions, for example, GTPase activator activity, protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by RGS3 itself. We selected most functions RGS3 had, and list some proteins which have the same functions with RGS3. You can find most of the proteins on our site.

Function Related Protein
GTPase activator activityLRRK2;ASAP1A;CDC42EP1;ASAP2;ARHGAP26;ARHGAP42A;RASA1;RIN3;TBC1D15
protein bindingSETMAR;GRASP;MAP1LC3C;CENPW;MED10;TLN1;FTH1;RAB7L1;EXOSC3

RGS3 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with RGS3 here. Most of them are supplied by our site. Hope this information will be useful for your research of RGS3.

PLSCR1; YWHAZ; ACD; YWHAB; HES4; yopM; yscP; yscH; isftu1; q7arn6_yerpe; prlA; aslA1; deoB; ycgQ; alsS; GORASP2

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