RGS3
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Official Full Name
regulator of G-protein signaling 3
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Overview
This gene encodes a member of the regulator of G-protein signaling (RGS) family. This protein is a GTP-ase activating protein which inhibits G-protein mediated signal transduction. The protein is largely cytosolic, but G-protein activation leads to translocation of this protein to the plasma membrane. A nuclear form of this protein has also been described, but its sequence has not been identified. Multiple alternatively spliced transcript variants have been described for this gene but the full-length nature of some transcripts is not yet known. -
Synonyms
RGS3; regulator of G-protein signaling 3; regulator of G protein signalling 3; C2PA; FLJ20370; PDZ RGS3; regulator of G-protein signalling 3; RGP3; PDZ-RGS3; FLJ31516; FLJ90496;
- Recombinant Proteins
- Cell & Tissue Lysates
- Protein Pre-coupled Magnetic Beads
- Chicken
- Human
- Mouse
- Rat
- E.coli
- HEK293
- HEK293T
- In Vitro Cell Free System
- Mammalian Cell
- Wheat Germ
- C
- Myc
- DDK
- GST
- His
- His (Fc)
- Avi
- His|T7
- N/A
- Involved Pathway
- Protein Function
- Interacting Protein
RGS3 involved in several pathways and played different roles in them. We selected most pathways RGS3 participated on our site, such as Axon guidance, which may be useful for your reference. Also, other proteins which involved in the same pathway with RGS3 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
Pathway Name | Pathway Related Protein |
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Axon guidance | FRS2;SEMA4D;DCC;NTN1B;NRG2A;AP2M1;SEMA5B;KBTBD7;RHOD |
RGS3 has several biochemical functions, for example, GTPase activator activity, protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by RGS3 itself. We selected most functions RGS3 had, and list some proteins which have the same functions with RGS3. You can find most of the proteins on our site.
Function | Related Protein |
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GTPase activator activity | LRRK2;ASAP1A;CDC42EP1;ASAP2;ARHGAP26;ARHGAP42A;RASA1;RIN3;TBC1D15 |
protein binding | SETMAR;GRASP;MAP1LC3C;CENPW;MED10;TLN1;FTH1;RAB7L1;EXOSC3 |
RGS3 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with RGS3 here. Most of them are supplied by our site. Hope this information will be useful for your research of RGS3.
PLSCR1; YWHAZ; ACD; YWHAB; HES4; yopM; yscP; yscH; isftu1; q7arn6_yerpe; prlA; aslA1; deoB; ycgQ; alsS; GORASP2
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