rgs3
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  • Official Full Name
  • regulator of G-protein signaling 3
  • Background
  • This gene encodes a member of the regulator of G-protein signaling (RGS) family. This protein is a GTP-ase activating protein which inhibits G-protein mediated signal transduction. The protein is largely cytosolic, but G-protein activation leads to translocation of this protein to the plasma membrane. A nuclear form of this protein has also been described, but its sequence has not been identified. Multiple alternatively spliced transcript variants have been described for this gene but the full-length nature of some transcripts is not yet known.
  • Synonyms
  • RGS3; regulator of G-protein signaling 3; regulator of G protein signalling 3; C2PA; FLJ20370; PDZ RGS3; regulator of G-protein signalling 3; RGP3; PDZ-RGS3; FLJ31516; FLJ90496
Cat.#:RGS3-2280HTag:GST
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human RGS3, GST-tagged
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Cat.#:RGS3-29967THTag:
Source (Host):Wheat germSpecies:Human
Product nameRecombinant Human RGS3
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Cat.#:RGS3-392HTag:His
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human RGS3 Protein, His-tagged
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Cat.#:RGS3-14144MTag:His
Source (Host):Mammalian CellsSpecies:Mouse
Product nameRecombinant Mouse RGS3 Protein
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Cat.#:Rgs3-8186MTag:His/T7
Source (Host):E. coliSpecies:Mouse
Product nameRecombinant Mouse Rgs3 protein, His & T7-tagged
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Cat.#:RGS3-5019RTag:His
Source (Host):Mammalian CellsSpecies:Rat
Product nameRecombinant Rat RGS3 Protein
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Cat.#:RGS3-6029CTag:His
Source (Host):Mammalian CellsSpecies:Chicken
Product nameRecombinant Chicken RGS3
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Cat.#:RGS3-2373HCLTag:
Source (Host):Species:Human
Product nameRecombinant Human RGS3 293 Cell Lysate
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Cat.#:RGS3-2374HCLTag:
Source (Host):Species:Human
Product nameRecombinant Human RGS3 293 Cell Lysate
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Cat.#:RGS3-2375HCLTag:
Source (Host):Species:Human
Product nameRecombinant Human RGS3 293 Cell Lysate
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Cat.#:RGS3-2376HCLTag:
Source (Host):Species:Human
Product nameRecombinant Human RGS3 293 Cell Lysate
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Involved Pathway

RGS3 involved in several pathways and played different roles in them. We selected most pathways RGS3 participated on our site, such as Axon guidance, which may be useful for your reference. Also, other proteins which involved in the same pathway with RGS3 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
Pathway Name
Pathway Related Protein
Axon guidance
CSK; SDCBP; L1CAM; PAK2; CXCL12; JAK3; Ntng2; COL9A1A; SPTB; ARPC2

Protein Function

RGS3 has several biochemical functions, for example, GTPase activator activity, protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by RGS3 itself. We selected most functions RGS3 had, and list some proteins which have the same functions with RGS3. You can find most of the proteins on our site.
Function
Related Protein
Function GTPase activator activity
Related Protein GIT1; DOCK1; ARHGEF19; GIT2B; RASA3; ARHGAP25; ELMOD1; TBC1D22A; ARFGAP2; FAM13B1
Function protein binding
Related Protein SPTSSB; ARMCX5; C19orf25; CD151; SNAPIN; ACSS1; RRP8; VAMP2; CREB3L1; HSPA4

Interacting Protein

RGS3 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with RGS3 here. Most of them are supplied by our site. Hope this information will be useful for your research of RGS3.
PLSCR1; YWHAZ; ACD; YWHAB; HES4; yopM; yscP; yscH; isftu1; q7arn6_yerpe; prlA; aslA1; deoB; ycgQ; alsS; GORASP2