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RGS5

  • Official Full Name

    regulator of G-protein signaling 5

  • Overview

    This gene encodes a member of the regulators of G protein signaling (RGS) family. The RGS proteins are signal transduction molecules which are involved in the regulation of heterotrimeric G proteins by acting as GTPase activators. This gene is a hypoxia-inducible factor-1 dependent, hypoxia-induced gene which is involved in the induction of endothelial apoptosis. This gene is also one of three genes on chromosome 1q contributing to elevated blood pressure. Alternatively spliced transcript variants encoding different isoforms have been identified.
  • Synonyms

    RGS5; regulator of G-protein signaling 5; regulator of G protein signalling 5; MST092; MST106; MST129; MSTP032; MSTP092; MSTP106; MSTP129; RGS 5; RGS5_HUMAN;

  • Recombinant Proteins
  • Cell & Tissue Lysates
  • Protein Pre-coupled Magnetic Beads
  • Human
  • Mouse
  • Rhesus Macaque
  • E.coli
  • HEK293
  • Mammalian Cell
  • GST
  • His
  • His (Fc)
  • Avi
  • His|T7
  • N/A
Species Cat.# Product name Source (Host) Tag Protein Length Price
Human RGS5-31322TH Recombinant Human RGS5, His-tagged E.coli His 181 amino acids
Human RGS5-3617H Recombinant Human RGS5, His-tagged E.coli His
Human RGS5-384H Recombinant Human RGS5, His-tagged E.coli His Met1-Lys181
Human RGS5-2371HCL Recombinant Human RGS5 293 Cell Lysate HEK293 N/A
Human RGS5-301392H Recombinant Human RGS5 protein, GST-tagged E.coli GST Met1-Lys181
Mouse Rgs5-8187M Recombinant Mouse Rgs5 protein, His & T7-tagged E.coli His/T7 Met1~Lys181 (Accession # O08850)
Mouse RGS5-14146M Recombinant Mouse RGS5 Protein Mammalian Cell His
Mouse RGS5-7569M Recombinant Mouse RGS5 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Mouse RGS5-7569M-B Recombinant Mouse RGS5 Protein Pre-coupled Magnetic Beads HEK293
Rhesus Macaque RGS5-3876R Recombinant Rhesus monkey RGS5 Protein, His-tagged Mammalian Cell His
Rhesus Macaque RGS5-3693R Recombinant Rhesus Macaque RGS5 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Rhesus Macaque RGS5-3693R-B Recombinant Rhesus Macaque RGS5 Protein Pre-coupled Magnetic Beads HEK293
  • Involved Pathway
  • Protein Function
  • Interacting Protein

RGS5 involved in several pathways and played different roles in them. We selected most pathways RGS5 participated on our site, such as Calcium Regulation in the Cardiac Cell, Myometrial Relaxation and Contraction Pathways, which may be useful for your reference. Also, other proteins which involved in the same pathway with RGS5 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name Pathway Related Protein
Calcium Regulation in the Cardiac CellANXA6;GJB4;GJA5;RGS18;CX34.4;RGS19;RGS16;GNG13B;GJB5
Myometrial Relaxation and Contraction PathwaysCORIN;RAMP3;CRH;RXFP2;CNN2;GABPB1;GABPA;MYLK2;CRHR1

RGS5 has several biochemical functions, for example, GTPase activator activity. Some of the functions are cooperated with other proteins, some of the functions could acted by RGS5 itself. We selected most functions RGS5 had, and list some proteins which have the same functions with RGS5. You can find most of the proteins on our site.

Function Related Protein
GTPase activator activityARHGAP29;DOCK1;CDC42EP2;MURC;AGFG1B;CDC42EP4A;DEPDC1A;RAP1GDS1;ELMOD1

RGS5 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with RGS5 here. Most of them are supplied by our site. Hope this information will be useful for your research of RGS5.

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