ror2
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  • Official Full Name
  • receptor tyrosine kinase-like orphan receptor 2
  • Background
  • ROR1 and ROR2 are orphan receptor tyrosine kinases that are most closely related to MuSK and the Trk family of neurotrophin receptors. They are characterized by the presence of extracellular frizzled-like cysteine-rich domains and membrane-proximal kringl
  • Synonyms
  • ROR2; receptor tyrosine kinase-like orphan receptor 2; BDB, BDB1, NTRKR2; tyrosine-protein kinase transmembrane receptor ROR2; neurotrophic tyrosine kinase receptor-related 2; BDB; BDB1; NTRKR2; MGC163394
Cat.#:ROR2-183HATag:Fc
Source (Host):HEK293 CellsSpecies:Human
Product nameRecombinant Human ROR2 protein, Fc-tagged, APC labeled
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Cat.#:ROR2-183HPTag:Fc
Source (Host):HEK293 CellsSpecies:Human
Product nameRecombinant Human ROR2 protein, Fc-tagged, R-PE labeled
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Cat.#:ROR2-313HTag:His
Source (Host):HEK293Species:Human
Product nameRecombinant Human ROR2 Protein, His-tagged
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Cat.#:ROR2-314MTag:Fc
Source (Host):HEK293Species:Mouse
Product nameRecombinant Mouse ROR2 Protein, Fc-tagged
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Cat.#:ROR2-666HTag:His-Avi
Source (Host):HEK293Species:Human
Product nameRecombinant Human ROR2 Protein, His-Avi-tagged, Biotinylated
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Cat.#:ROR2-1184HTag:His/GST
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human ROR2 protein, His & GST-tagged
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Cat.#:ROR2-183HTag:Fc
Source (Host):HEK293Species:Human
Product nameRecombinant Human ROR2, Fc-tagged
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Cat.#:ROR2-30436THTag:GST
Source (Host):Species:Human
Product nameRecombinant Human ROR2, GST-tagged
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Cat.#:ROR2-423HTag:GST
Source (Host):Sf 9 Insect cellsSpecies:Human
Product nameRecombinant Human ROR2, GST-tagged, Active
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Cat.#:ROR2-667HTag:His
Source (Host):Human cellsSpecies:Human
Product nameRecombinant Human ROR2, His-tagged, Biotinylated
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Cat.#:ROR2-668HTag:Fc
Source (Host):Human cellsSpecies:Human
Product nameRecombinant Human ROR2, Fc-tagged, Biotinylated
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Cat.#:ROR2-669HTag:His
Source (Host):Human cellsSpecies:Human
Product nameRecombinant Human ROR2, His-tagged
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Cat.#:ROR2-757HTag:DDK/His
Source (Host):HEK293 cellsSpecies:Human
Product nameRecombinant Human ROR2 Protein, DDK/His-tagged
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Cat.#:ROR2-758HTag:DDK
Source (Host):Sf9 cellsSpecies:Human
Product nameRecombinant Human ROR2 Protein, DDK-tagged
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Cat.#:ROR2-799HTag:MYC/DDK
Source (Host):HEK293Species:Human
Product nameRecombinant Human ROR2 Protein, MYC/DDK-tagged
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Cat.#:ROR2-3611CTag:His
Source (Host):Mammalian CellsSpecies:Chicken
Product nameRecombinant Chicken ROR2
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Involved Pathway

ROR2 involved in several pathways and played different roles in them. We selected most pathways ROR2 participated on our site, such as Beta-catenin independent WNT signaling, Cardiac Progenitor Differentiation, Noncanonical Wnt signaling pathway, which may be useful for your reference. Also, other proteins which involved in the same pathway with ROR2 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
Pathway Name
Pathway Related Protein
Beta-catenin independent WNT signaling
PRICKLE1B; CLTB; CLTC; GNB5; AGO2; AP2M1; DVL1; MOV10; AGO3; DVL2
Cardiac Progenitor Differentiation
TBX5; NKX2; NIPAL1; T; ROR2; LIN28B; IRX4; ZFP42; TBX20; BMP1
Noncanonical Wnt signaling pathway
ROR2; CHD7; CTHRC1
PCP/CE pathway
PRICKLE1B; PRICKLE1; RYK; ROR2; ROR1
Signal Transduction
RLN1; GNA13B; LPAR2B; APOA4B.2; VIP2; RSPO2; KIF7; ARHGAP22; CRABP2B; S1PR3
Signaling by Wnt
GPR177; RSPO3; CDC73; PRICKLE1B; TMED5; WIF1; RNF43; ROR2; PRICKLE1; KLHL12
WNT5A-dependent internalization of FZD2, FZD5 and ROR2
ROR1; ROR2
Wnt Signaling Pathway NetPath
BCL9; NR5A1; TAX1BP3; SALL1; ROR2; BRD7; PAX2; MAP1B; MTAP1B; TFAP2A

Protein Function

ROR2 has several biochemical functions, for example, ATP binding, Wnt-protein binding, frizzled binding. Some of the functions are cooperated with other proteins, some of the functions could acted by ROR2 itself. We selected most functions ROR2 had, and list some proteins which have the same functions with ROR2. You can find most of the proteins on our site.
Function
Related Protein
Function ATP binding
Related Protein PDPK1A; SPG7; MYH7B; MCM3L; ATP7A; DDX49; EIF2B2; ALK; KITA; CTPS1A
Function Wnt-protein binding
Related Protein WLS; FZD8B; SZL; FZD9B; SFRP4; CTHRC1; GM12824; SFRP2; ROR1; LRP5L
Function frizzled binding
Related Protein WNT8A; WNT7AA; DVL3A; WNT16; RSPO3; WNT4B; DVL1B; WNT2; WNT11; LRP6
Function metal ion binding
Related Protein KLF12; ZNF543; PVALB4; BTK; CYP2AA1; ZSCAN21; ENTPD7; PLA2G2F; Car8; AARS
Function protein binding
Related Protein C16orf72; NCSTN; NFATC2; ARHGEF2; RNF115; VPS72; MED26; ANKRD27; HSPA12B; ATF3
Function transmembrane receptor protein tyrosine kinase activity
Related Protein ERBB2; EPHB4A; DDR2; EPHB4; IGF1RA; DDR1; EGFRA; ERBB4; EPHA4B; NTRK1

Interacting Protein

ROR2 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with ROR2 here. Most of them are supplied by our site. Hope this information will be useful for your research of ROR2.
HSP90AB1

ROR2 Related Articles

Ishizuya-Oka, A; Kajita, M; et al. Thyroid Hormone-Regulated Wnt5a/Ror2 Signaling Is Essential for Dedifferentiation of Larval Epithelial Cells into Adult Stem Cells in the Xenopus laevis Intestine. PLOS ONE 9:-(2014).
Bauer, M; Benard, J; et al. WNT5A Encodes Two Isoforms with Distinct Functions in Cancers. PLOS ONE 8:-(2013).