RPL12 Protein, ribosomal protein L12

RPL12

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RPL12

Official Full Name ribosomal protein L12
Background Ribosomes, the organelles that catalyze protein synthesis, consist of a small 40S subunit and a large 60S subunit. Together these subunits are composed of 4 RNA species and approximately 80 structurally distinct proteins. This gene encodes a ribosomal protein that is a component of the 60S subunit. The protein belongs to the L11P family of ribosomal proteins. It is located in the cytoplasm. The protein binds directly to the 26S rRNA. This gene is co-transcribed with the U65 snoRNA, which is located in its fourth intron. As is typical for genes encoding ribosomal proteins, there are multiple processed pseudogenes of this gene dispersed through the genome.
Synonyms RPL12; ribosomal protein L12; 60S ribosomal protein L12; L12
    • Species :
    • Chicken
    • Human
    • Mouse
    • Rhesus Macaque
    • Zebrafish
    • Source :
    • E.coli
    • HEK293
    • Mammalian Cell
    • Wheat Germ
    • Tag :
    • His
    • N/A
    Species Cat.# Product name Source (Host) Tag Protein Length Price
    Human RPL12-2227HCL Recombinant Human RPL12 293 Cell Lysate HEK293 N/A
    Human RPL12-31150TH Recombinant Human RPL12 Wheat Germ N/A
    Human RPL12-7529H Recombinant Human RPL12, His-tagged E.coli His
    Mouse RPL12-14407M Recombinant Mouse RPL12 Protein Mammalian Cell His
    Rhesus Macaque RPL12-3972R Recombinant Rhesus monkey RPL12 Protein, His-tagged Mammalian Cell His
    Chicken RPL12-5056C Recombinant Chicken RPL12 Mammalian Cell His
    Zebrafish RPL12-11566Z Recombinant Zebrafish RPL12 Mammalian Cell His

    RPL12 involved in several pathways and played different roles in them. We selected most pathways RPL12 participated on our site, such as Ribosome, which may be useful for your reference. Also, other proteins which involved in the same pathway with RPL12 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein
    Ribosome RPS8; MRPS11; MRPL23; RPS17L; RPS16; RPS24; MRPS17; RPL36AL; RPS5; RPL11

    RPL12 has several biochemical functions, for example, poly(A) RNA binding, protein binding, rRNA binding. Some of the functions are cooperated with other proteins, some of the functions could acted by RPL12 itself. We selected most functions RPL12 had, and list some proteins which have the same functions with RPL12. You can find most of the proteins on our site.

    Function Related Protein
    poly(A) RNA binding ILF3; EZR; NQO1; HERC5; CCDC108; RBM26; ZC3H8; NOP2; PRPF3; RPS15
    protein binding POLI; AGFG1; HMMR; DPYSL5; C7orf59; RAB3C; SERPINC1; AVPI1; RAD9B; RAPGEF6
    rRNA binding RPS4Y2; PTCD3; RPF2; KDM2B; RPS4Y1; RPL12; MRPL20; TLR13; SBDS; RPS5
    structural constituent of ribosome RPS26; MRPS5; RPL8; RPL15; RPL38; RPS9; RPL5A; MRPS25; SLC25A47A; MRPL33

    RPL12 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with RPL12 here. Most of them are supplied by our site. Hope this information will be useful for your research of RPL12.

    CANX; ZNF16; TUBA4A; CBX1; TTN; UBE2O; midostaurin; NOP56; GABARAP; FN1; ESR1; US11; VIM; VCAM1; RPL10

    Delage, L; Giege, P; et al. Four paralogues of RPL12 are differentially associated to ribosome in plant mitochondria. BIOCHIMIE 89:658-668(2007).
    SCHMIDT, J; BUBUNENKO, M; et al. A NOVEL OPERON ORGANIZATION INVOLVING THE GENES FOR CHORISMATE SYNTHASE (AROMATIC BIOSYNTHESIS PATHWAY) AND RIBOSOMAL GTPASE CENTER PROTEINS (L11, L1, L10, L12-RPLKAJL) IN CYANOBACTERIUM SYNECHOCYSTIS PCC 6803. JOURNAL OF BIOLOGICAL CHEMISTRY 268:27447-27457(1993).
    CRITTEND.LB; OKAZAKI, W; et al. GENETIC INFLUENCE OF RS LOCUS ON SUSCEPTIBILITY TO AVIAN TUMOR VIRUSES .2. ROUS SARCOMA VIRUS ANTIBODY PRODUCTION AFTER STRAIN RPL12 VIRUS INOCULATION. JOURNAL OF THE NATIONAL CANCER INSTITUTE 36:299-&(1966).

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