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Official Full Name RuvB-like 1
Background RuvB-like 1 (E. coli), also known as RUVBL1 and TIP49, is a human gene. RUVBL1 can form a hexamer. The hexamer can form a dodecamer with RUVBL2 protein.
Synonyms RUVBL1; RuvB-like 1 (E. coli); RuvB (E coli homolog) like 1; ruvB-like 1; ECP54; INO80 complex subunit H; INO80H; NMP238; pontin; Pontin52; RVB1; TIH1; TIP49; TIP49a; ECP-54; NMP 238; pontin 52; TAP54-alpha; nuclear matrix protein 238; RuvB (E coli
    • Species :
    • Chicken
    • Human
    • Mouse
    • Rat
    • Rhesus Macaque
    • Zebrafish
    • Source :
    • E.coli
    • HEK293
    • HEK293T
    • Insect Cell
    • Mammalian Cell
    • Tag :
    • GST
    • His
    • Myc/DDK
    • Myc
    • DDK
    • N/A
    Species Cat.# Product name Source (Host) Tag Protein Length Price
    Human RUVBL1-1814H Recombinant Human RUVBL1 Protein, Myc/DDK-tagged, C13 and N15-labeled HEK293T Myc/DDK
    Mouse Ruvbl1-5653M Recombinant Mouse Ruvbl1 Protein, Myc/DDK-tagged HEK293T Myc/DDK
    Human RUVBL1-001HCL Recombinant Human RUVBL1 cell lysate Insect Cell N/A
    Human RUVBL1-2009H Recombinant Human RUVBL1 Protein, MYC/DDK-tagged HEK293 Myc/DDK
    Human RUVBL1-2475H Recombinant Human RUVBL1, GST-tagged E.coli GST
    Human RUVBL1-2733H Recombinant Human RuvB-like 1 (E. coli), His-tagged E.coli His
    Human RUVBL1-30681TH Recombinant Human RUVBL1, His-tagged E.coli His
    Human RUVBL1-8637H Recombinant Human RUVBL1, His tagged Insect Cell His
    Mouse RUVBL1-14593M Recombinant Mouse RUVBL1 Protein Mammalian Cell His
    Rat RUVBL1-5203R Recombinant Rat RUVBL1 Protein Mammalian Cell His
    Rhesus Macaque RUVBL1-4055R Recombinant Rhesus monkey RUVBL1 Protein, His-tagged Mammalian Cell His
    Chicken RUVBL1-1290C Recombinant Chicken RUVBL1 Mammalian Cell His
    Zebrafish RUVBL1-9559Z Recombinant Zebrafish RUVBL1 Mammalian Cell His

    RUVBL1 involved in several pathways and played different roles in them. We selected most pathways RUVBL1 participated on our site, such as Wnt signaling pathway, which may be useful for your reference. Also, other proteins which involved in the same pathway with RUVBL1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein
    Wnt signaling pathway CER1; FZD3B; WNT16; WNT11R; BAMBIB; FZD8; PLCB3; FZD9; RAC3B; WNT11

    RUVBL1 has several biochemical functions, for example, ATP binding, NOT ATPase activity, DNA helicase activity. Some of the functions are cooperated with other proteins, some of the functions could acted by RUVBL1 itself. We selected most functions RUVBL1 had, and list some proteins which have the same functions with RUVBL1. You can find most of the proteins on our site.

    Function Related Protein
    ATP binding SMC1B; MLH1; MAP4K4; LACE1; TRPV1; LANCL2; KIF2A; ATP2A2; PRPF4BB; DDX51
    NOT ATPase activity KIF26A; RUVBL1; MYO18A; CLU
    DNA helicase activity RUVBL2; FBXO18; MCM2; RECQL; PEO1; WRN; MCM6L; ATRX; PIF1; INO80
    protein binding PTPN4; C5; ARL2; NPM3; UBR1; MGRN1; LILRA4; KREMEN1; PAM; THBS4

    RUVBL1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with RUVBL1 here. Most of them are supplied by our site. Hope this information will be useful for your research of RUVBL1.


    Lacombe, J; Mange, A; et al. A Multiparametric Serum Marker Panel as a Complementary Test to Mammography for the Diagnosis of Node-Negative Early-Stage Breast Cancer and DCIS in Young Women. CANCER EPIDEMIOLOGY BIOMARKERS & PREVENTION 23:1834-1842(2014).
    Kaji, K; Fertig, N; et al. Autoantibodies to RuvBL1 and RuvBL2: A Novel Systemic Sclerosis-Related Antibody Associated With Diffuse Cutaneous and Skeletal Muscle Involvement. ARTHRITIS CARE & RESEARCH 66:575-584(2014).

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