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SCD

Official Full Name

stearoyl-CoA desaturase (delta-9-desaturase)
Overview

This gene encodes an enzyme involved in fatty acid biosynthesis, primarily the synthesis of oleic acid. Transcripts of approximately 3.9 and 5.2 kb, differing only by alternative polyadenlyation signals, have been detected. A gene encoding a similar enzyme is located on chromosome 4 and a pseudogene of this gene is located on chromosome 17. [provided by RefSeq, Feb 2012]
Synonyms

SCD; stearoyl-CoA desaturase (delta-9-desaturase); SCD1; FADS5; SCDOS; MSTP008; acyl-CoA desaturase; delta-9 desaturase; delta-9-desaturase; delta(9)-desaturase; fatty acid desaturase; predicted protein of HQ0998; stearoyl-CoA desaturase opposite strand;

Type

Recombinant Proteins
Cell & Tissue Lysates
Protein Pre-coupled Magnetic Beads

Species

Bos taurus (Bovine)
Chicken
Goat
Homo sapiens (Human)
Human
Mesocricetus auratus (Golden hamster)
Ovis aries (Sheep)
Rat
Sus scrofa (Pig)
Zebrafish

Source

E.coli
E.coli expression system
E.Coli or Yeast
HEK293
In vitro E. coli expression system
Mammalian Cell
Wheat Germ

Tag

GST
His
His (Fc)
Avi
N/A
N

Species	Cat.#	Product name	Source (Host)	Tag	Protein Length	Price
Human	SCD-3126H	Recombinant Human SCD, His-tagged	E.Coli or Yeast	His	359	Inquiry
Human	SCD-28H	Recombinant Human SCD protein, GST-tagged	Wheat Germ	GST		Inquiry
Human	SCD-2044HCL	Recombinant Human SCD 293 Cell Lysate	HEK293	N/A		Inquiry
Human	SCD-2394H	Recombinant Human SCD protein, His-tagged	E.coli	His	1-359aa	Inquiry
Human	SCD-2726H	Recombinant Human SCD Full Length Transmembrane protein (1-359 aa), His-tagged	In vitro E. coli expression system	His	1-359aa	Inquiry
Rat	SCD-5246R	Recombinant Rat SCD Protein	Mammalian Cell	His		Inquiry
Rat	SCD-4905R	Recombinant Rat SCD Protein, His (Fc)-Avi-tagged	HEK293	His (Fc)-Avi		Inquiry
Rat	SCD-4905R-B	Recombinant Rat SCD Protein Pre-coupled Magnetic Beads	HEK293			Inquiry
Bos taurus (Bovine)	RFL19383BF	Recombinant Full Length Bovine Acyl-Coa Desaturase(Scd) Protein, His-Tagged	E.coli expression system	His	Full Length of Mature Protein (2-359)	Inquiry
Goat	RFL4212CF	Recombinant Full Length Goat Acyl-Coa Desaturase(Scd) Protein, His-Tagged	E.coli expression system	His	Full Length of Mature Protein (2-359)	Inquiry
Homo sapiens (Human)	RFL7559HF	Recombinant Full Length Human Acyl-Coa Desaturase(Scd) Protein, His-Tagged	E.coli expression system	His	Full Length (1-359aa)	Inquiry
Mesocricetus auratus (Golden hamster)	RFL34573MF	Recombinant Full Length Mesocricetus Auratus Acyl-Coa Desaturase(Scd) Protein, His-Tagged	E.coli expression system	His	Full Length of Mature Protein (2-354)	Inquiry
Ovis aries (Sheep)	RFL15797OF	Recombinant Full Length Sheep Acyl-Coa Desaturase(Scd) Protein, His-Tagged	E.coli expression system	His	Full Length of Mature Protein (2-359)	Inquiry
Sus scrofa (Pig)	RFL4237SF	Recombinant Full Length Pig Acyl-Coa Desaturase(Scd) Protein, His-Tagged	E.coli expression system	His	Full Length (1-334)	Inquiry
Zebrafish	SCD-9849Z	Recombinant Zebrafish SCD	Mammalian Cell	His		Inquiry
Zebrafish	scd-2743Z	Recombinant Zebrafish scd Protein, His&GST-tagged	E.coli	N-His&GST	His87-Arg183	Inquiry
Chicken	SCD-6453C	Recombinant Chicken SCD	Mammalian Cell	His		Inquiry

Involved Pathway
Protein Function
Interacting Protein
SCD Related Articles

SCD involved in several pathways and played different roles in them. We selected most pathways SCD participated on our site, such as Biosynthesis of unsaturated fatty acids, Fatty acid metabolism, PPAR signaling pathway, which may be useful for your reference. Also, other proteins which involved in the same pathway with SCD were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name	Pathway Related Protein
Biosynthesis of unsaturated fatty acids	ACOT5;SCD5;ACOX1;HADHAA;HSD17B12A;PTPLAD1;ACOT7;HADHA;TECRB
Fatty acid metabolism	ACSL3B;CPT1B;MCAT;ACOX3;ACADSB;HSD17B12B;ACSL4;SCD;ACADVL
PPAR signaling pathway	SLC27A1A;FABP7;ACOX2;ACSL4;FABP4;UCP1;UBC;ACSL1;SCD
AMPK signaling pathway	CRTC2;IRS1;CREB1;CAMKK1;CCNA1;LEPR;PRKAB2;CPT1C;PRKAG1

SCD has several biochemical functions, for example, iron ion binding, oxidoreductase activity, stearoyl-CoA 9-desaturase activity. Some of the functions are cooperated with other proteins, some of the functions could acted by SCD itself. We selected most functions SCD had, and list some proteins which have the same functions with SCD. You can find most of the proteins on our site.

Function	Related Protein
iron ion binding	POR;HBE;NFU1;FTL;CYP4A10;CYP26B1;SC5D;NDOR1;NOS2B
oxidoreductase activity	PDHA1A;CYP2AA12;PYROXD2;P4HA1A;CYP17A2;LDHBA;HSDL1;GPD1;AIFM4
stearoyl-CoA 9-desaturase activity	SCD5;FADS2;SCD;Scd1;Scd2

SCD has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with SCD here. Most of them are supplied by our site. Hope this information will be useful for your research of SCD.

MYC; E2F3

Noizat-Pirenne, F; Habibi, A; et al. The use of rituximab to prevent severe delayed haemolytic transfusion reaction in immunized patients with sickle cell disease. VOX SANGUINIS 108:262-267(2015).

Rieux, C; De Meyer, E; et al. Delayed hemolytic transfusion reaction in sicle cell disease patients: A new challenge for the Hemovigilance network. TRANSFUSION CLINIQUE ET BIOLOGIQUE 22:37-41(2015).