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Official Full Name stearoyl-CoA desaturase (delta-9-desaturase)
Background This gene encodes an enzyme involved in fatty acid biosynthesis, primarily the synthesis of oleic acid. Transcripts of approximately 3.9 and 5.2 kb, differing only by alternative polyadenlyation signals, have been detected. A gene encoding a similar enzyme is located on chromosome 4 and a pseudogene of this gene is located on chromosome 17. [provided by RefSeq, Feb 2012]
Synonyms SCD; stearoyl-CoA desaturase (delta-9-desaturase); SCD1; FADS5; SCDOS; MSTP008; acyl-CoA desaturase; delta-9 desaturase; delta-9-desaturase; delta(9)-desaturase; fatty acid desaturase; predicted protein of HQ0998; stearoyl-CoA desaturase opposite strand;
    • Species :
    • Chicken
    • Human
    • Rat
    • Zebrafish
    • Source :
    • E.Coli or Yeast
    • HEK293
    • in vitro E. coli
    • Mammalian Cell
    • Wheat Germ
    • Tag :
    • GST
    • His
    • N/A
    Species Cat.# Product name Source (Host) Tag Protein Length Price
    Human SCD-2726H Recombinant Human SCD Protein (1-359 aa), His-tagged in vitro E. coli His
    Human SCD-2044HCL Recombinant Human SCD 293 Cell Lysate HEK293 N/A
    Human SCD-28H Recombinant Human SCD protein, GST-tagged Wheat Germ GST
    Human SCD-3126H Recombinant Human SCD, His-tagged E.Coli or Yeast His
    Rat SCD-5246R Recombinant Rat SCD Protein Mammalian Cell His
    Chicken SCD-6453C Recombinant Chicken SCD Mammalian Cell His
    Zebrafish SCD-9849Z Recombinant Zebrafish SCD Mammalian Cell His

    SCD involved in several pathways and played different roles in them. We selected most pathways SCD participated on our site, such as Biosynthesis of unsaturated fatty acids, Fatty acid metabolism, PPAR signaling pathway, which may be useful for your reference. Also, other proteins which involved in the same pathway with SCD were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein
    Biosynthesis of unsaturated fatty acids ELOVL6; ACAA1A; HADHA; ACOT7; HSD17B12A; SCD5; ACAA1; PTPLAD1; ACOX3; PTPLA
    Fatty acid metabolism MCAT; ELOVL5; FADS1; TECRB; ACAT1; EHHADH; HADH; PPT1; HSD17B12A; ACADS
    PPAR signaling pathway FABP5; ACSL1B; ACOX3; GK; PCK2; FABP7A; FABP3; APOA1; PDPK1B; FABP7B
    AMPK signaling pathway EEF2; PRKAG1; LEP; G6PC2; LEPR; FBP2; Scd2; ADIPOQ; PPP2R5B; FBP1

    SCD has several biochemical functions, for example, iron ion binding, oxidoreductase activity, stearoyl-CoA 9-desaturase activity. Some of the functions are cooperated with other proteins, some of the functions could acted by SCD itself. We selected most functions SCD had, and list some proteins which have the same functions with SCD. You can find most of the proteins on our site.

    Function Related Protein
    iron ion binding CYP2D26; HBBE2; CYP2A12; HBE; CYP46A1.2; CYP27C1; CYP2V1; KDM3A; P4HA1; SC4MOL
    oxidoreductase activity Scd2; CYB5RL; ERO1L; AKR1A1B; CYP2AA7; RDH13; CYP2C8; SDR42E1; CYP2AA2; ALDH3A2A
    stearoyl-CoA 9-desaturase activity SCD5; SCD; Scd2; Scd1; FADS2

    SCD has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with SCD here. Most of them are supplied by our site. Hope this information will be useful for your research of SCD.

    MYC; E2F3

    Noizat-Pirenne, F; Habibi, A; et al. The use of rituximab to prevent severe delayed haemolytic transfusion reaction in immunized patients with sickle cell disease. VOX SANGUINIS 108:262-267(2015).
    Rieux, C; De Meyer, E; et al. Delayed hemolytic transfusion reaction in sicle cell disease patients: A new challenge for the Hemovigilance network. TRANSFUSION CLINIQUE ET BIOLOGIQUE 22:37-41(2015).

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