sec13
Share
  • Official Full Name
  • SEC13 homolog (S. cerevisiae)
  • Background
  • The protein encoded by this gene belongs to the SEC13 family of WD-repeat proteins. It is a constituent of the endoplasmic reticulum and the nuclear pore complex. It has similarity to the yeast SEC13 protein, which is required for vesicle biogenesis from endoplasmic reticulum during the transport of proteins. Multiple alternatively spliced transcript variants have been found.
  • Synonyms
  • SEC13; SEC13 homolog (S. cerevisiae); D3S1231E, SEC13 (S. cerevisiae) like 1 , SEC13 like 1 (S. cerevisiae) , SEC13L1; protein SEC13 homolog; npp 20; SEC13R; D3S1231E; Npp20; SEC13 (S. cerevisiae) like 1; SEC13 homolog; SEC13 like 1 (S. cerevisiae); SEC13 like 1 isoform; SEC13 like protein 1; SEC13 protein; SEC13 related protein; SEC13-like protein 1; SEC13-related protein; SEC13_HUMAN; SEC13L1; SEC13-like 1 isoform; npp-20
Cat.#:SEC13-3505HTag:His
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human S100 Aalcium Binding Protein A16, His-tagged
+Inquiry
Cat.#:SEC13-14819MTag:His
Source (Host):Mammalian CellsSpecies:Mouse
Product nameRecombinant Mouse SEC13 Protein
+Inquiry
Cat.#:SEC13-5298RTag:His
Source (Host):Mammalian CellsSpecies:Rat
Product nameRecombinant Rat SEC13 Protein
+Inquiry
Cat.#:SEC13-4120RTag:His
Source (Host):Mammalian CellsSpecies:Rhesus Macaque
Product nameRecombinant Rhesus monkey SEC13 Protein, His-tagged
+Inquiry
Cat.#:SEC13-5193CTag:His
Source (Host):Mammalian CellsSpecies:Chicken
Product nameRecombinant Chicken SEC13
+Inquiry
Cat.#:SEC13-12520ZTag:His
Source (Host):Mammalian CellsSpecies:Zebrafish
Product nameRecombinant Zebrafish SEC13
+Inquiry
Cat.#:SEC13-2000HCLTag:
Source (Host):Species:Human
Product nameRecombinant Human SEC13 293 Cell Lysate
+Inquiry

Involved Pathway

SEC13 involved in several pathways and played different roles in them. We selected most pathways SEC13 participated on our site, such as RNA transport, Protein processing in endoplasmic reticulum, which may be useful for your reference. Also, other proteins which involved in the same pathway with SEC13 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
Pathway Name
Pathway Related Protein
RNA transport
GEMIN4; EIF3E; SARNP; PEAK1; PABPC1L; PABPC5; NUP188; UBE2I; NUP107; NMD3
Protein processing in endoplasmic reticulum
P4HB; RRBP1B; SVIP; EIF2AK4; CUL1; HSPA1A; DNAJB1B; HSP90AA1.2; AMFR; MAP3K5

Protein Function

SEC13 has several biochemical functions, for example, protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by SEC13 itself. We selected most functions SEC13 had, and list some proteins which have the same functions with SEC13. You can find most of the proteins on our site.
Function
Related Protein
Function protein binding
Related Protein PTPRS; OFCC1; KCNA1; TCTE3; RALYL; GET4; C1orf182; ACTN2; GBP1; ADRB2

Interacting Protein

SEC13 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with SEC13 here. Most of them are supplied by our site. Hope this information will be useful for your research of SEC13.
NUP145; TRAF5; Nup98; Nup107; SEC16B

SEC13 Related Articles

Siddiqi, S; Mansbach, CM; et al. Phosphorylation of Sar1b Protein Releases Liver Fatty Acid-binding Protein from Multiprotein Complex in Intestinal Cytosol Enabling It to Bind to Endoplasmic Reticulum (ER) and Bud the Pre-chylomicron Transport Vesicle. JOURNAL OF BIOLOGICAL CHEMISTRY 287:10178-10188(2012).
Sihn, CR; Suh, EJ; et al. Sec13 induces genomic instability in U2OS cells. EXPERIMENTAL AND MOLECULAR MEDICINE 37:255-260(2005).