serpine2
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  • Official Full Name
  • serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2
  • Background
  • Glia-derived nexin is a protein that in humans is encoded by the SERPINE2 gene.
  • Synonyms
  • SERPINE2; serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2; PI7, serine (or cysteine) proteinase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2; glia-derived nexin; GDN; glial derived nexin 1; nexin; PN1; PNI; Glia derived nexin; Protease inhibitor 7; GDN_HUMAN; P17; Peptidase inhibitor 7; Pi-7; Plasminogen activator inhibitor type 1, member 2; PN-1; Protease nexin 1; Protease nexin I; Serpin E2; SERPINE 2; OTTHUMP00000164215; OTTHUMP00000203766; OTTHUMP00000203767; OTTHUMP00000203768; glial-derived neurite promoting factor; PI7
Cat.#:SERPINE2-187HTag:His
Source (Host):HEK293Species:Human
Product nameRecombinant Human SERPINE2, His-tagged
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Cat.#:SERPINE2-2601HTag:GST
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human SERPINE2, GST-tagged
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Cat.#:SERPINE2-2602HTag:GST
Source (Host):Wheat germSpecies:Human
Product nameRecombinant Human SERPINE2, GST-tagged
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Cat.#:SERPINE2-688HTag:His
Source (Host):NSO cellsSpecies:Human
Product nameRecombinant Human SERPINE2, His-tagged
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Cat.#:SERPINE2-8004HTag:His/T7
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human SERPINE2 protein, His & T7-tagged
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Cat.#:SERPINE2-14959MTag:His
Source (Host):Mammalian CellsSpecies:Mouse
Product nameRecombinant Mouse SERPINE2 Protein
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Cat.#:Serpine2-2599MTag:N/A
Source (Host):E. coliSpecies:Mouse
Product nameRecombinant Mouse Serpine2
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Cat.#:SERPINE2 -92RTag:N/A
Source (Host):E. coliSpecies:Rabbit
Product nameRecombinant Rabbit PAI-1 biotin labeled latent fraction
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Cat.#:SERPINE2 -93RTag:N/A
Source (Host):E. coliSpecies:Rabbit
Product nameRecombinant Rabbit PAI-1 stable mutant
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Cat.#:SERPINE2 -94RTag:N/A
Source (Host):E. coliSpecies:Rabbit
Product nameRecombinant Rabbit PAI-1 wild type latent
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Cat.#:SERPINE2-3683CTag:His
Source (Host):Mammalian CellsSpecies:Chicken
Product nameRecombinant Chicken SERPINE2
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Cat.#:SERPINE2-10530ZTag:His
Source (Host):Mammalian CellsSpecies:Zebrafish
Product nameRecombinant Zebrafish SERPINE2
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Cat.#:Serpine2-1308MTag:N/A
Source (Host):Baculovirus-Insect CellsSpecies:Mouse
Product nameRecombinant Mouse Serine (or cysteine) Peptidase Inhibitor, Clade E, Member 2
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Cat.#:Serpine2-2600RTag:N/A
Source (Host):E. coliSpecies:Rat
Product nameRecombinant Rat Serpine2
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Cat.#:SERPINE2-1937HCLTag:
Source (Host):Species:Human
Product nameRecombinant Human SERPINE2 293 Cell Lysate
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Involved Pathway

Serpine2 involved in several pathways and played different roles in them. We selected most pathways Serpine2 participated on our site, such as Common Pathway of Fibrin Clot Formation, Dissolution of Fibrin Clot, Formation of Fibrin Clot (Clotting Cascade), which may be useful for your reference. Also, other proteins which involved in the same pathway with Serpine2 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
Pathway Name
Pathway Related Protein
Common Pathway of Fibrin Clot Formation
SERPINE2; PRTN3; CFHL2; CFHL1; PROCR; F13A1B; SERPINA1L; LOC100514666; PROCA; CFHL3
Dissolution of Fibrin Clot
ANXA2A; SERPINF2B; ANXA2B; S100A10; S100A10A; HRG; S100A10B; SERPINE2; SERPINB8; ANXA2
Formation of Fibrin Clot (Clotting Cascade)
LOC100514666; F13A1B; F3B; PROCR; PROCA; F3A; F9B; CFHL3; CFHL4; SERPINA1L
Hemostasis
C6orf25; EHD1; CABLES2; BA1L; F3B; SCG3; CFHL2; GATA5; CEACAM6; PRTN3
Intrinsic Pathway of Fibrin Clot Formation
PROCA; F9B; F9A; SERPINE2; SERPINA1L

Protein Function

Serpine2 has several biochemical functions, for example, glycosaminoglycan binding, heparin binding, protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by Serpine2 itself. We selected most functions Serpine2 had, and list some proteins which have the same functions with Serpine2. You can find most of the proteins on our site.
Function
Related Protein
Function glycosaminoglycan binding
Related Protein BGN; EPYC; VIT; SERPINE2; DCN; HABP2; ENG; PODXL2; SPOCK2; TGFBR2
Function heparin binding
Related Protein FGFR4; THBS1; ADAMTS1; SERPINC1; CTGFA; LRPAP1; COL20A1; C6orf25; PF4V1; APOH
Function protein binding
Related Protein PPAP2B; RAD51L3; RPGRIP1; ITGA3; SNRPN; ASB2; FGFR2; PLCE1; TMEM171; ROR2
Function receptor binding
Related Protein NSG1; GSDMA2; WNT5B; IL28A; NRXN1; NPFF; PLA2G1B; APOL2; POU2F1; PVRL3B
Function serine-type endopeptidase inhibitor activity
Related Protein TFPIA; WFDC13; SERPINH1; ITIH1; SERPINA1L; A2M; HRG; WFDC2; EPPIN; SERPINB1L2

Interacting Protein

Serpine2 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with Serpine2 here. Most of them are supplied by our site. Hope this information will be useful for your research of Serpine2.
FAM9B

Serpine2 Related Articles

Lu, CH; Lee, RKK; et al. Involvement of the Serine Protease Inhibitor, SERPINE2, and the Urokinase Plasminogen Activator in Cumulus Expansion and Oocyte Maturation. PLOS ONE 8:-(2013).
Boulaftali, Y; Francois, D; et al. Endothelial Protease Nexin-1 Is a Novel Regulator of A Disintegrin and Metalloproteinase 17 Maturation and Endothelial Protein C Receptor Shedding via Furin Inhibition. ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY 33:1647-1654(2013).