slc2a1
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  • Official Full Name
  • solute carrier family 2 (facilitated glucose transporter), member 1
  • Background
  • This gene encodes a major glucose transporter in the mammalian blood-brain barrier. The encoded protein is found primarily in the cell membrane and on the cell surface, where it can also function as a receptor for human T-cell leukemia virus (HTLV) I and II. Mutations in this gene have been found in a family with paroxysmal exertion-induced dyskinesia. [provided by RefSeq, Apr 2013]
  • Synonyms
  • SLC2A1; solute carrier family 2 (facilitated glucose transporter), member 1; PED; DYT9; GLUT; DYT17; DYT18; EIG12; GLUT1; HTLVR; GLUT1DS; solute carrier family 2, facilitated glucose transporter member 1; GLUT-1; hepG2 glucose transporter; glucose transporter type 1, erythrocyte/brain; human T-cell leukemia virus (I and II) receptor;
Cat.#:SLC2A1-1753HTag:His/SUMO
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human SLC2A1 protein, His & SUMO-tagged
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Cat.#:SLC2A1-2741HTag:His
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human SLC2A1, His-tagged
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Cat.#:SLC2A1-2742HTag:MYC/DDK
Source (Host):HEK293Species:Human
Product nameRecombinant Human SLC2A1 protein, MYC/DDK-tagged
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Cat.#:SLC2A1-15359MTag:His
Source (Host):Mammalian CellsSpecies:Mouse
Product nameRecombinant Mouse SLC2A1 Protein
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Cat.#:SLC2A1-5495RTag:His
Source (Host):Mammalian CellsSpecies:Rat
Product nameRecombinant Rat SLC2A1 Protein
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Cat.#:SLC2A1-4263RTag:His
Source (Host):Mammalian CellsSpecies:Rhesus Macaque
Product nameRecombinant Rhesus monkey SLC2A1 Protein, His-tagged
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Cat.#:SLC2A1-6762CTag:His
Source (Host):Mammalian CellsSpecies:Chicken
Product nameRecombinant Chicken SLC2A1
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Involved Pathway

SLC2A1 involved in several pathways and played different roles in them. We selected most pathways SLC2A1 participated on our site, such as HIF- signaling pathway, Insulin secretion, Thyroid hormone signaling pathway, which may be useful for your reference. Also, other proteins which involved in the same pathway with SLC2A1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
Pathway Name
Pathway Related Protein
HIF- signaling pathway
MAPK3; BCL2; NFKB1; ANGPT2; PDHB; IFNG; PIK3R5; INS; ANGPT1; TCEB1
Insulin secretion
PRKCG; KCNJ11; KCNN4; KCNMA1; STX1A; ATF4; ATP1A4; INS; CAMK2G; GIP
Thyroid hormone signaling pathway
TSC2; ESR1; SLC2A1; NCOA3; PIK3CG; MED12L; HDAC1; ATP1B4; MED17; MAPK3
Adipocytokine signaling pathway
ACSBG1; POMC; ACACB; PRKAG3; PTPN11; CAMKK2; ACSL1; LEP; NFKBIAB; PRKAB1
Glucagon signaling pathway
GCGR; PPP3CB; PHKA2; SIRT1; PFKL; PPARGC1A; PRMT1; CREB3L3; PYGB; PFKFB1
Insulin resistance
CREB3L1; PRKCZ; CREB5; PTENA; PCK2; OGT; PRKCE; NOS3; RPS6KAL; RPS6KB1
Bile secretion
SCTR; SLC27A5; SULT2A1; ATP1B3; CYP7A1; PRKACG; CFTR; ATP1A2; ABCC3; SLC5A1
HTLV-I infection
CALR; EGR2; CDC20; CCNB2; LTBR; PTTG1; CCND1; TSPO; EP300; ANAPC11
Pathways in cancer
CTBP2; TRAF6; LPAR4; GNG5; CXCR4; TRAF3; ROCK2; GSK3B; MITF; FLT3LG
Renal cell carcinoma
PIK3CB; MAP2K1; PIK3R5; RBX1; MAP2K2; PAK3; PIK3CD; ARNT2; RAP1B; PIK3R2
Central carbon metabolism in cancer
FGFR1; PIK3R1; G6PDX; KRAS; PDGFRA; MAPK3; NRAS; SLC1A5; G6PD; PTEN

Protein Function

SLC2A1 has several biochemical functions, for example, D-glucose transmembrane transporter activity, dehydroascorbic acid transporter activity, glucose transmembrane transporter activity. Some of the functions are cooperated with other proteins, some of the functions could acted by SLC2A1 itself. We selected most functions SLC2A1 had, and list some proteins which have the same functions with SLC2A1. You can find most of the proteins on our site.
Function
Related Protein
Function D-glucose transmembrane transporter activity
Related Protein SLC2A4; SLC2A2; SLC2A1; SLC2A13B
Function dehydroascorbic acid transporter activity
Related Protein SLC2A2; SLC23A1; SLC2A1
Function glucose transmembrane transporter activity
Related Protein SLC2A1A; SLC2A11B; SLC2A4; SLC2A6; SLC2A5; SLC2A15A; PPBP; SLC2A2; SLC2A15B; SLC2A9L1
Function identical protein binding
Related Protein SID4; ALCAMB; POU3F2; KCNJ10; TPRG1L; MPZL2B; CALHM1; PTK6; BTK; PCNA
Function kinase binding
Related Protein PPP1R9B; TENC1; C2orf44; JAKMIP3; PFKL; FAS; WWC3; CDC37; CTNNB1; SGOL1
Function protein binding
Related Protein HOOK3; THY1; SCRN2; ADCY6; TRAM2; HIST1H4B; PDZD7; MYL12A; HDAC1; NR2E3
Function protein self-association
Related Protein TMEM43; TTN; DYRK1A; BCL10; ZKSCAN17; L1CAM; RYR2; LDB1; PROSAPIP1; TRIM32
Function xenobiotic transporter activity
Related Protein SLC2A1

Interacting Protein

SLC2A1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with SLC2A1 here. Most of them are supplied by our site. Hope this information will be useful for your research of SLC2A1.
VCAM1; COPS6; E2F3; JAK2; STK17B; ATF2; TYK2; Bmpr1a; Cct8