SLC2A1

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SLC2A1

Official Full Name solute carrier family 2 (facilitated glucose transporter), member 1
Background This gene encodes a major glucose transporter in the mammalian blood-brain barrier. The encoded protein is found primarily in the cell membrane and on the cell surface, where it can also function as a receptor for human T-cell leukemia virus (HTLV) I and II. Mutations in this gene have been found in a family with paroxysmal exertion-induced dyskinesia. [provided by RefSeq, Apr 2013]
Synonyms SLC2A1; solute carrier family 2 (facilitated glucose transporter), member 1; PED; DYT9; GLUT; DYT17; DYT18; EIG12; GLUT1; HTLVR; GLUT1DS; solute carrier family 2, facilitated glucose transporter member 1; GLUT-1; hepG2 glucose transporter; glucose transporter type 1, erythrocyte/brain; human T-cell leukemia virus (I and II) receptor;
    • Species :
    • Chicken
    • Human
    • Mouse
    • Rat
    • Rhesus Macaque
    • Source :
    • E.coli
    • HEK293
    • Mammalian Cell
    • Tag :
    • His
    • SUMO
    • Myc
    • DDK
    Species Cat.# Product name Source (Host) Tag Protein Length Price
    Human SLC2A1-1753H Recombinant Human SLC2A1 protein, His & SUMO-tagged E.coli His/SUMO
    Human SLC2A1-2741H Recombinant Human SLC2A1, His-tagged E.coli His
    Human SLC2A1-2742H Recombinant Human SLC2A1 protein, MYC/DDK-tagged HEK293 Myc/DDK
    Mouse SLC2A1-15359M Recombinant Mouse SLC2A1 Protein Mammalian Cell His
    Rat SLC2A1-5495R Recombinant Rat SLC2A1 Protein Mammalian Cell His
    Rhesus Macaque SLC2A1-4263R Recombinant Rhesus monkey SLC2A1 Protein, His-tagged Mammalian Cell His
    Chicken SLC2A1-6762C Recombinant Chicken SLC2A1 Mammalian Cell His

    SLC2A1 involved in several pathways and played different roles in them. We selected most pathways SLC2A1 participated on our site, such as HIF- signaling pathway, Insulin secretion, Thyroid hormone signaling pathway, which may be useful for your reference. Also, other proteins which involved in the same pathway with SLC2A1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein
    HIF- signaling pathway RELA; GM5506; CAMK2A; CAMK2G; BCL2; LTBR; EIF4E1B; EGLN1; MKNK1; PRKCB
    Insulin secretion KCNN3; STX1A; CREB3L1; CREB5; PRKACA; PCLO; ITPR3; GNAQ; GCG; INS2
    Thyroid hormone signaling pathway RAF1; PFKP; TSC2; MED17; PLN; BAD; MDM2; MED1; TP53; ATP2A2
    Adipocytokine signaling pathway SOCS3B; ACSL5; RXRG; PRKAB1; JAK2; ACSL4A; RXRB; NFKBIA; ACSL4B; RXRA
    Glucagon signaling pathway AKT2; PRKAG3; SLC2A2; PHKG1; PRMT1; PYGL; CALM2; PGAM2; CALM4; LDHC
    Insulin resistance PRKAB2; NR1H2; MTOR; PRKCE; GSK3AA; AKT2; SOCS3; G6PCA.1; GSK3B; PTENA
    Bile secretion ADCY6; ABCB1A; AQP4; HMGCR; RXRA; SLC10A2; Abcb1b; AQP8; NCEH1; SLC2A1
    HTLV-I infection POLE; WNT8A; FZD10; HLA-A; NRAS; PDGFRB; SRF; CALR; ANAPC5; ATF1
    Pathways in cancer RXRA; PRKCG; FGF14; EGLN1; Ar; GNG11; NFKB2; RALGDS; SLC2A1; FGF13
    Renal cell carcinoma AKT1; PIK3R2; PAK1; AKT2; TCEB1; MET; PIK3CG; AHA-1; PAK2; EP300
    Central carbon metabolism in cancer NRAS; SCO2; AKT2; PIK3R3; GLS2; PDGFRA; HKDC1; PGAM2; SIRT6; KRAS

    SLC2A1 has several biochemical functions, for example, D-glucose transmembrane transporter activity, dehydroascorbic acid transporter activity, glucose transmembrane transporter activity. Some of the functions are cooperated with other proteins, some of the functions could acted by SLC2A1 itself. We selected most functions SLC2A1 had, and list some proteins which have the same functions with SLC2A1. You can find most of the proteins on our site.

    Function Related Protein
    D-glucose transmembrane transporter activity SLC2A4; SLC2A1; SLC2A2; SLC2A13B
    dehydroascorbic acid transporter activity SLC2A1; SLC2A2; SLC23A1
    glucose transmembrane transporter activity SLC2A1; SLC2A8; PPBP; SLC2A15A; SLC2A1A; SLC2A5; SLC2A3; SLC2A15B; SLC2A3A; SLC2A2
    identical protein binding NCL; EWSR1; DNM1; PRMT1; EED; FHIT; ZHX2; PUF60; PARP1; L3MBTL1
    kinase binding EMP2; PFKL; PER3; RPS3; BARD1; NTRK1; SRC; SGOL1; CEBPA; TRIP6
    protein binding SPATC1; ACTR3; ITGB1BP1; DDX41; THRAA; SERTAD3; CHD8; SYCP1; STX12; C16orf59
    protein self-association ADAM8; CNTN2; TRP53; L1CAM; AGXT; CBR2; AGA; ZKSCAN17; SVIP; AGTR1B
    xenobiotic transporter activity SLC2A1

    SLC2A1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with SLC2A1 here. Most of them are supplied by our site. Hope this information will be useful for your research of SLC2A1.

    VCAM1; COPS6; E2F3; JAK2; STK17B; ATF2; TYK2; Bmpr1a; Cct8

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